Michael G. Irving

Matrix metalloproteinase localisation by in situ-RT-PCR in archival human breast biopsy material (2008)

Haupt, Larisa, Irving, Rachel, Weinstein, Stephen Rudolph, Irving, Michael G., Griffiths, Lyn

Utilising archival human breast cancer biopsy material we examined the stromal/epithelial interactions of several matrix metalloproteinases (MMPs) using in situ-RT-PCR (IS-RT-PCR). In breast cancer,...

Matrix metalloproteinase localisation by in situ-RT-PCR in archival human breast biopsy material (2008)

Haupt, Larisa, Irving, Rachel, Weinstein, Stephen Rudolph, Irving, Michael G., Griffiths, Lyn

Utilising archival human breast cancer biopsy material we examined the stromal/epithelial interactions of several matrix metalloproteinases (MMPs) using in situ-RT-PCR (IS-RT-PCR). In breast cancer,...

In vitroand in vivoMMP gene expression localisation by In Situ-RT-PCR in cell culture and paraffin embedded human breast cancer cell line xenografts (2006)

Haupt, Larisa M, Thompson, Erik W, Trezise, Ann EO, Irving, Rachel E, Irving, Michael G, Griffiths, Lyn R

Abstract Background Members of the matrix metalloproteinase (MMP) family of proteases are required for the degradation of the basement membrane and extracellular matrix in both normal and...

Stimulation of MMP-11 (stromelysin-3) expression in mouse fibroblasts by cytokines, collagen and co-culture with human breast cancer cell lines (2004)

Selvey, Saxon, Haupt, Larisa M, Thompson, Erik W, Matthaei, Klaus I, Irving, Michael G, Griffiths, Lyn R

Abstract Background Matrix metalloproteinases (MMPs) are central to degradation of the extracellular matrix and basement membrane during both normal and carcinogenic tissue remodeling. MT1-MMP...

The Electronic Medical Record at the Medical University of South Carolina: Successful Integration of Multiple Commercial “Best of Breed” Systems

Afrin, Lawrence B., Northrup, David J., Daniels, Mark R., Irving, Michael G.

Over a 15 year period, MUSC has implemented an evolving set of commercially available “best of breed” clinical information systems throughout the enterprise. Successful systems integration...