The BRCT domain of mammalian Pes1 is crucial for nucleolar localization and rRNA processing (2007)
Hölzel, Michael, Grimm, Thomas, Rohrmoser, Michaela, Malamoussi, Anastassia, Harasim, Thomas, Gruber-Eber, Anita, ...
The nucleolar protein Pes1 interacts with Bop1 and WDR12 in a stable complex (PeBoW-complex) and its expression is tightly associated with cell proliferation. The yeast homologue Nop7p (Yph1p)...
Rapid conditional knock-down-knock-in system for mammalian cells (2007)
Hölzel, Michael, Rohrmoser, Michaela, Orban, Mathias, Hömig, Cornelia, Harasim, Thomas, Malamoussi, Anastassia, ...
RNA interference (RNAi) is a powerful tool to analyze gene function in mammalian cells. However, the interpretation of RNAi knock-down phenotypes can be hampered by off-target effects or compound...
Grimm, Thomas, Hölzel, Michael, Rohrmoser, Michaela, Harasim, Thomas, Malamoussi, Anastassia, Gruber-Eber, Anita, ...
The nucleolar PeBoW-complex, consisting of Pes1, Bop1 and WDR12, is essential for cell proliferation and processing of ribosomal RNA in mammalian cells. Here we have analysed the physical and...
Rapid conditional knock-down-knock-in system for mammalian cells (2006)
Hölzel, Michael, Rohrmoser, Michaela, Orban, Mathias, Hömig, Cornelia, Harasim, Thomas, Malamoussi, Anastassia, ...
RNA interference (RNAi) is a powerful tool to analyze gene function in mammalian cells. However, the interpretation of RNAi knock-down phenotypes can be hampered by off-target effects or compound...
The BRCT domain of mammalian Pes1 is crucial for nucleolar localization and rRNA processing (2006)
Hölzel, Michael, Grimm, Thomas, Rohrmoser, Michaela, Malamoussi, Anastassia, Harasim, Thomas, Gruber-Eber, Anita, ...
The nucleolar protein Pes1 interacts with Bop1 and WDR12 in a stable complex (PeBoW-complex) and its expression is tightly associated with cell proliferation. The yeast homologue Nop7p (Yph1p)...
Rapid conditional knock-down-knock-in system for mammalian cells (2006)
Hölzel, Michael, Rohrmoser, Michaela, Orban, Mathias, Hömig, Cornelia, Harasim, Thomas, Malamoussi, Anastassia, ...
RNA interference (RNAi) is a powerful tool to analyze gene function in mammalian cells. However, the interpretation of RNAi knock-down phenotypes can be hampered by off-target effects or compound...
The BRCT domain of mammalian Pes1 is crucial for nucleolar localization and rRNA processing (2006)
Hölzel, Michael, Grimm, Thomas, Rohrmoser, Michaela, Malamoussi, Anastassia, Harasim, Thomas, Gruber-Eber, Anita, ...
The nucleolar protein Pes1 interacts with Bop1 and WDR12 in a stable complex (PeBoW-complex) and its expression is tightly associated with cell proliferation. The yeast homologue Nop7p (Yph1p)...
Bornkamm, Georg W., Berens, Christian, Kuklik-Roos, Conny, Bechet, Jean-Marie, Laux, Gerhard, Bachl, Jürgen, ...
Conditional expression systems are of pivotal importance for the dissection of complex biological phenomena. Here, we describe a novel EBV-derived episomally replicating plasmid (pRTS-1) that carries...
A role for c-Myc in the regulation of ribosomal RNA processing (2003)
Schlosser, Isabel, Hölzel, Michael, Mürnseer, Marlies, Burtscher, Helmut, Weidle, Ulrich H., Eick, Dirk
The proto‐oncogene c‐myc encodes a basic helix–loop–helix leucine zipper transcription factor (c‐Myc) that has a profound role in growth control and cell cycle progression....
The transcriptional program of a human B cell line in response to Myc (2001)
Schuhmacher, Marino, Kohlhuber, Franz, Hölzel, Michael, Kaiser, Carmen, Burtscher, Helmut, Jarsch, Michael, ...
The proto-oncogene c-myc (myc) encodes a transcription factor (Myc) that promotes growth, proliferation and apoptosis. Myc has been suggested to induce these effects by induction/repression of...
The transcriptional program of a human B cell line in response to Myc
Schuhmacher, Marino, Kohlhuber, Franz, Hölzel, Michael, Kaiser, Carmen, Burtscher, Helmut, Jarsch, Michael, ...
The proto-oncogene c-myc (myc) encodes a transcription factor (Myc) that promotes growth, proliferation and apoptosis. Myc has been suggested to induce these effects by induction/repression of...
A role for c-Myc in the regulation of ribosomal RNA processing
Schlosser, Isabel, Hölzel, Michael, Mürnseer, Marlies, Burtscher, Helmut, Weidle, Ulrich H., Eick, Dirk
The proto-oncogene c-myc encodes a basic helix–loop–helix leucine zipper transcription factor (c-Myc) that has a profound role in growth control and cell cycle progression. Previous microarray...
Myc/Max/Mad regulate the frequency but not the duration of productive cell cycles
Hölzel, Michael, Kohlhuber, Franz, Schlosser, Isabel, Hölzel, Dieter, Lüscher, Bernhard, Eick, Dirk
Upregulation of the proto-oncoprotein Myc, a basic, helix–loop–helix, leucin zipper domain transcription factor has profound consequences on cell proliferation, cell growth and apoptosis. Cell...
Stringent doxycycline-dependent control of gene activities using an episomal one-vector system
Bornkamm, Georg W., Berens, Christian, Kuklik-Roos, Conny, Bechet, Jean-Marie, Laux, Gerhard, Bachl, Jürgen, ...
Conditional expression systems are of pivotal importance for the dissection of complex biological phenomena. Here, we describe a novel EBV-derived episomally replicating plasmid (pRTS-1) that carries...
Grimm, Thomas, Hölzel, Michael, Rohrmoser, Michaela, Harasim, Thomas, Malamoussi, Anastassia, Gruber-Eber, Anita, ...
The nucleolar PeBoW-complex, consisting of Pes1, Bop1 and WDR12, is essential for cell proliferation and processing of ribosomal RNA in mammalian cells. Here we have analysed the physical and...
The transcriptional program of a human B cell line in response to Myc
Schuhmacher, Marino, Kohlhuber, Franz, Hölzel, Michael, Kaiser, Carmen, Burtscher, Helmut, Jarsch, Michael, ...
The proto-oncogene c-myc (myc) encodes a transcription factor (Myc) that promotes growth, proliferation and apoptosis. Myc has been suggested to induce these effects by induction/repression of...
A role for c-Myc in the regulation of ribosomal RNA processing
Schlosser, Isabel, Hölzel, Michael, Mürnseer, Marlies, Burtscher, Helmut, Weidle, Ulrich H., Eick, Dirk
The proto-oncogene c-myc encodes a basic helix–loop–helix leucine zipper transcription factor (c-Myc) that has a profound role in growth control and cell cycle progression. Previous microarray...
Myc/Max/Mad regulate the frequency but not the duration of productive cell cycles
Hölzel, Michael, Kohlhuber, Franz, Schlosser, Isabel, Hölzel, Dieter, Lüscher, Bernhard, Eick, Dirk
Upregulation of the proto-oncoprotein Myc, a basic, helix–loop–helix, leucin zipper domain transcription factor has profound consequences on cell proliferation, cell growth and apoptosis. Cell...
Stringent doxycycline-dependent control of gene activities using an episomal one-vector system
Bornkamm, Georg W., Berens, Christian, Kuklik-Roos, Conny, Bechet, Jean-Marie, Laux, Gerhard, Bachl, Jürgen, ...
Conditional expression systems are of pivotal importance for the dissection of complex biological phenomena. Here, we describe a novel EBV-derived episomally replicating plasmid (pRTS-1) that carries...
Grimm, Thomas, Hölzel, Michael, Rohrmoser, Michaela, Harasim, Thomas, Malamoussi, Anastassia, Gruber-Eber, Anita, ...
The nucleolar PeBoW-complex, consisting of Pes1, Bop1 and WDR12, is essential for cell proliferation and processing of ribosomal RNA in mammalian cells. Here we have analysed the physical and...
Rapid conditional knock-down–knock-in system for mammalian cells
Hölzel, Michael, Rohrmoser, Michaela, Orban, Mathias, Hömig, Cornelia, Harasim, Thomas, Malamoussi, Anastassia, ...
RNA interference (RNAi) is a powerful tool to analyze gene function in mammalian cells. However, the interpretation of RNAi knock-down phenotypes can be hampered by off-target effects or compound...
The BRCT domain of mammalian Pes1 is crucial for nucleolar localization and rRNA processing
Hölzel, Michael, Grimm, Thomas, Rohrmoser, Michaela, Malamoussi, Anastassia, Harasim, Thomas, Gruber-Eber, Anita, ...
The nucleolar protein Pes1 interacts with Bop1 and WDR12 in a stable complex (PeBoW-complex) and its expression is tightly associated with cell proliferation. The yeast homologue Nop7p (Yph1p)...
Rohrmoser, Michaela, Hölzel, Michael, Grimm, Thomas, Malamoussi, Anastassia, Harasim, Thomas, Orban, Mathias, ...
The PeBoW complex is essential for cell proliferation and maturation of the large ribosomal subunit in mammalian cells. Here we examined the role of PeBoW-specific proteins Pes1, Bop1, and WDR12 in...
Hölzel, Michael, Rohrmoser, Michaela, Schlee, Martin, Grimm, Thomas, Harasim, Thomas, Malamoussi, Anastassia, ...
Target genes of the protooncogene c-myc are implicated in cell cycle and growth control, yet the linkage of both is still unexplored. Here, we show that the products of the nucleolar target genes...
Faumont, Nathalie, Durand-Panteix, Stéphanie, Schlee, Martin, Grömminger, Sebastian, Schuhmacher, Marino, Hölzel, Michael, ...
The Epstein-Barr virus (EBV) latency III program imposed by EBNA2 and LMP1 is directly responsible for immortalization of B cells in vitro and is thought to mediate most immunodeficiency-related...