Michael Höpfner

Forschungszentrum Karlsruhe (2008)

Technik Und Umwelt, Ra Zimmermann, Thomas Blumenstock, Frank Hase, Michael Höpfner, Dmitry Yashcov

Derivation of PSC properties from ground based FTIR measurements at Kiruna (Sweden) on January 26 th, 2000

Charakterisierung polarer stratosphärischer Wolken mittels hochauflösender Infrarotspektroskopie (2008)

Höpfner, Michael

Polare stratosphärische Wolken (PSCs) spielen für die Ozonchemie der winterlichen Stratosphäre eine herausragende Rolle. Wechselwirkungen zwischen der abkühlenden Stratosphäre und der Existenz...

OVERVIEW OF MIPAS OPERATIONAL PRODUCTS (2007)

Raspollini, Piera, Aubertin, Ginette, Bartha, Sven, Birk, Manfred, Carli, Bruno, Carlotti, Massimo, ...

After 2 years of quasi continuously operations (from July 2002 to March 2004), MIPAS on ENVISAT was stopped due to problems in the mirror drive of the interferometer. Operations with reduced spectral...

Estimating cirrus cloud properties from MIPAS data (2007)

Mendrok, Jana, Schreier, Franz, Höpfner, Michael

High resolution mid-infrared limb emission spectra observed by the spaceborne Michelson Interferometer for Passive Atmospheric Sounding (MIPAS) showing evidence of cloud interference are analyzed....

A novel approach in the treatment of neuroendocrine gastrointestinal tumors: Additive antiproliferative effects of interferon-γ and meta-iodobenzylguanidine (2004)

Höpfner, Michael, Sutter, Andreas P, Huether, Alexander, Ahnert-Hilger, Gudrun, Scherübl, Hans

Abstract Background Therapeutic options to effectively inhibit growth and spread of neuroendocrine gastrointestinal tumors are still limited. As both meta-iodobenzylguanidine (MIBG) and interferon-γ...

Advanced MIPAS-Level-2 Data Analysis (AMIL2DA) (2003)

Clarmann Von, Thomas, Birk, Manfred, Bovensmann, Heinrich, Bracher, Astrid, Burgess, Alastair, Cecherini, Simone, ...

The Michelson Interferometer for Passive Atmospheric Sounding (MIPAS), which is a core instrument of the Envisat polar platform launched on 1 March 2002 by the European Space Agency (ESA), is a...

Very early chlorine activation and ozone loss in the Arctic winter 2002–2003 (2003)

Tilmes, Simone, Müller, Rolf, Grooß, Jens-Uwe, Höpfner, Michael, Toon, Geoffrey C., Russell III, James M.

To view the published open abstract, go to http://dx.doi.org/10.1029/2003GL018079 . An edited version of this paper was published by AGU. Copyright 2003 American Geophysical Union.

Sequential and Joint Retrieval of Trace Gas Profiles (2002)

Schwarz, Gottfried, Hilgers, Siegfried, Kemnitzer, Holger, Steck, Tilman, Clarmann Von, Thomas, Höpfner, Michael, ...

A purely sequential retrieval of trace gas profiles from limb sounding measurements may lead to error propagation, especially in the case of water vapor retrieval. A joint (i.e. simultaneous)...

Trace Gas Retrieval Including Horizontal Gradients (2002)

Kemnitzer, Holger, Hilgers, Siegfried, Schwarz, Gottfried, Steck, Tilman, Clarmann Von, Thomas, Höpfner, Michael, ...

Der Einfluss horizontaler Gradienten auf das Retrieval von Vertikalprofilen wird demonstriert und analysiert.

Experience Gained with the MIPAS Level 2 Off-Line Processor (2001)

Hilgers, Siegfried, Kemnitzer, Holger, Ressel, Klaus, Schwarz, Gottfried, Steck, Tilman, Clarmann Von, Thomas, ...

Performance tests of the MIPAS level 2 off-line processor led to in-depth experiences with retrieval options and performance characteristics. These depend on various parameters like microwindows,...

Trace Gas Retrieval Including Horizontal Gradients (2000)

Kemnitzer, Holger, Hilgers, Siegfried, Schwarz, Gottfried, Steck, Tilman, Clarmann Von, Thomas, Höpfner, Michael, ...

The results of trace gas retrievals of limb sounding measurements will be affected by a horizontally inhomogeneous atmosphere. In this case, the horizontal gradients should be included in the...

Sequential and Joint Retrieval of Trace Gas Profiles (2000)

Schwarz, Gottfried, Hilgers, Siegfried, Kemnitzer, Holger, Steck, Tilman, Clarmann Von, Thomas, Höpfner, Michael, ...

We demonstrate that a joint (i.e. simultaneous) retrieval of atmospherical trace gases from limb sounding measurements can outperform a purely sequential retrieval of the same trace gases. The reason...

Experience Gained with the MIPAS Level 2 Off-Line Processor (2000)

Hilgers, Siegfried, Kemnitzer, Holger, Ressel, Klaus, Schwarz, Gottfried, Steck, Tilman, Clarmann Von, Thomas, ...

The experience gained with the MIPAS level 2 offline processor will be described. In particular, the layout of the processor will be explained and results for various trace gas retrievals will be...

Optimized forward model and retrieval scheme for MIPAS near− real−time data processing (2000)

Marco Ridolfi, Bruno Carli, Massimo Carlotti, Thomas Von Clarmann, Bianca M. Dinelli, Anu Dudhia, ...

The infrared emission limb sounder MIPAS (Michelson Interferometer for Passive Atmospheric Sounding) will be operated as an ESA core instrument on the ENVISAT-1 satellite. Near real time retrieval of...

Growth factor receptors and related signalling pathways as targets for novel treatment strategies of hepatocellular cancer

Höpfner, Michael, Schuppan, Detlef, Scherübl, Hans

Growth factors and their corresponding receptors are commonly overexpressed and/or dysregulated in many cancers including hepatocellular cancer (HCC). Clinical trials indicate that growth factor...

Structural Adaptation and Heterogeneity of Normal and Tumor Microvascular Networks

Pries, Axel R., Cornelissen, Annemiek J. M., Sloot, Anoek A., Hinkeldey, Marlene, Dreher, Matthew R., Höpfner, Michael, ...

Relative to normal tissues, tumor microcirculation exhibits high structural and functional heterogeneity leading to hypoxic regions and impairing treatment efficacy. Here, computational simulations...

Treatment of gastrointestinal neuroendocrine tumors with inhibitors of growth factor receptors and their signaling pathways: Recent advances and future perspectives

Höpfner, Michael, Schuppan, Detlef, Scherübl, Hans

The limited efficacy of conventional cytotoxic treatment regimes for advanced gastrointestinal neuroendocrine cancers emphasizes the need for novel and more effective medical treatment options....

Targeted medical therapy of biliary tract cancer: Recent advances and future perspectives

Höpfner, Michael, Schuppan, Detlef, Scherübl, Hans

The limited efficacy of cytotoxic therapy for advanced biliary tract and gallbladder cancers emphasizes the need for novel and more effective medical treatment options. A better understanding of the...