Michael J. Crawford

Multiple functionally redundant signals mediate targeting to the apicoplast in the apicomplexan parasite Toxoplasma gondii. Eukaryot. Cell 3:663–674 (2004)

Omar S. Harb, Bithi Chatterjee, Martin J. Fraunholz, Michael J. Crawford, Manami Nishi, David S. Roos

Most species of the protozoan phylum Apicomplexa harbor an endosymbiotic organelle—the apicoplast— acquired when an ancestral parasite engulfed a eukaryotic plastid-containing alga. Several...

THE PADDINGTON ALCOHOL TEST: A SHORT REPORT (2004)

Patton, Robert, Hilton, Catriona, Crawford, Michael J., Touquet, Robin

The Paddington Alcohol Test, designed to screen for alcohol related problems amongst those attending Accident and Emergency Departments, is presented in a slightly modified form. It concords fairly...

Multiple Functionally Redundant Signals Mediate Targeting to the Apicoplast in the Apicomplexan Parasite Toxoplasma gondii

Harb, Omar S., Chatterjee, Bithi, Fraunholz, Martin J., Crawford, Michael J., Nishi, Manami, Roos, David S.

Most species of the protozoan phylum Apicomplexa harbor an endosymbiotic organelle—the apicoplast—acquired when an ancestral parasite engulfed a eukaryotic plastid-containing alga. Several...

Multiple Functionally Redundant Signals Mediate Targeting to the Apicoplast in the Apicomplexan Parasite Toxoplasma gondii

Harb, Omar S., Chatterjee, Bithi, Fraunholz, Martin J., Crawford, Michael J., Nishi, Manami, Roos, David S.

Most species of the protozoan phylum Apicomplexa harbor an endosymbiotic organelle—the apicoplast—acquired when an ancestral parasite engulfed a eukaryotic plastid-containing alga. Several...

Mining the Plasmodium genome database to define organellar function: what does the apicoplast do?

Roos, David S, Crawford, Michael J, Donald, Robert G K, Fraunholz, Martin, Harb, Omar S, He, Cynthia Y, ...

Apicomplexan species constitute a diverse group of parasitic protozoa, which are responsible for a wide range of diseases in many organisms. Despite differences in the diseases they cause, these...

Toxoplasma gondii scavenges host-derived lipoic acid despite its de novo synthesis in the apicoplast

Crawford, Michael J, Thomsen-Zieger, Nadine, Ray, Manisha, Schachtner, Joachim, Roos, David S, Seeber, Frank

In contrast to other eukaryotes, which manufacture lipoic acid, an essential cofactor for several vital dehydrogenase complexes, within the mitochondrion, we show that the plastid (apicoplast) of the...

The Plastid of Toxoplasma gondii Is Divided by Association with the Centrosomes

Striepen, Boris, Crawford, Michael J., Shaw, Michael K., Tilney, Lewis G., Seeber, Frank, Roos, David S.

Apicomplexan parasites harbor a single nonphotosynthetic plastid, the apicoplast, which is essential for parasite survival. Exploiting Toxoplasma gondii as an accessible system for cell biological...