CLONAL ANALYSIS OF EXPRESSION OF EPITHELIAL ANTIGENS IN CULTURES OF NORMAL HUMAN BREAST (2008)
Isobel M. Brooks, Hilary J, A. Virginia Foster, Morag L. Ellison, Michael J. O'hare
Cells from normal human breast epithelium were cloned in monolayer culture and the clones were stained with monoclonal antibodies. Tissue was from reduction mammoplasty operations. Cloning...
Grigoriadis, Anita, Mackay, Alan, Reis-Filho, Jorge S, Steele, Dawn, Iseli, Christian, Stevenson, Brian J, ...
Abstract Introduction Diverse microarray and sequencing technologies have been widely used to characterise the molecular changes in malignant epithelial cells in breast cancers. Such gene expression...
Jones, Chris, Mackay, Alan, Grigoriadis, Anita, Cossu, Antonio, Reis-Filho, Jorge S., Fulford, Laura, ...
The normal duct-lobular system of the breast is lined by two epithelial cell types, inner luminal secretory cells and outer contractile myoepithelial cells. We have generated comprehensive expression...
Models of breast cancer: is merging human and animal models the future? (2003)
Kim, Jong B, O'Hare, Michael J, Stein, Robert
Abstract Survival rates of patients with early breast cancer in the United Kingdom and in the United States have improved steadily over the past 15 years. The only way to continue or even accelerate...
The mammary myoepithelial cell - Cinderella or ugly sister? (2000)
Lakhani, Sunil R, O'Hare, Michael J
Abstract The breast myoepithelial cell is the Cinderella of mammary biology. Although its contribution to benign and some malignant pathologies is recognised, it has been largely neglected in...
Pfau, Wolfgang, O'Hare, Michael J., Grover, Philip L., Phillips, David H.
When incubated in suspension with the heterocyclic aromatic amine food mutagens 2-amino-3-methylimidazo [4,5-f]quinoline (IQ) and 2-amino-3,4-dimethylimidazo[4,5-f]quinoline (MeIQ), human mammary...
Conditional immortalization of freshly isolated human mammary fibroblasts and endothelial cells
O'Hare, Michael J., Bond, Jacquelyn, Clarke, Catherine, Takeuchi, Yasuhiro, Atherton, Amanda J., Berry, Catherine, ...
Reports differ as to whether reconstitution of telomerase activity alone is sufficient for immortalization of different types of human somatic cells or whether additional activities encoded by other...
Shotgun sequencing of the human transcriptome with ORF expressed sequence tags
Dias Neto, Emmanuel, Garcia Correa, Ricardo, Verjovski-Almeida, Sergio, Briones, Marcelo R. S., Nagai, Maria Aparecida, Da Silva, Wilson, ...
Theoretical considerations predict that amplification of expressed gene transcripts by reverse transcription–PCR using arbitrarily chosen primers will result in the preferential amplification of...
The mammary myoepithelial cell - Cinderella or ugly sister?
Lakhani, Sunil R, O'Hare, Michael J
The breast myoepithelial cell is the Cinderella of mammary biology. Although its contribution to benign and some malignant pathologies is recognised, it has been largely neglected in molecular and...
Jongeneel, C. Victor, Iseli, Christian, Stevenson, Brian J., Riggins, Gregory J., Lal, Anita, Mackay, Alan, ...
Whereas information is rapidly accumulating about the structure and position of genes encoded in the human genome, less is known about the complexity and relative abundance of their expression in...
Smith, Patrice D., Crocker, Stephen J., Jackson-Lewis, Vernice, Jordan-Sciutto, Kelly L., Hayley, Shawn, Mount, Matthew P., ...
Recent evidence indicates that cyclin-dependent kinases (CDKs, cdks) may be inappropriately activated in several neurodegenerative conditions. Here, we report that cdk5 expression and activity are...
Models of breast cancer: is merging human and animal models the future?
Kim, Jong B, O'Hare, Michael J, Stein, Robert
Survival rates of patients with early breast cancer in the United Kingdom and in the United States have improved steadily over the past 15 years. The only way to continue or even accelerate this...
Conditional immortalization of freshly isolated human mammary fibroblasts and endothelial cells
O'Hare, Michael J., Bond, Jacquelyn, Clarke, Catherine, Takeuchi, Yasuhiro, Atherton, Amanda J., Berry, Catherine, ...
Reports differ as to whether reconstitution of telomerase activity alone is sufficient for immortalization of different types of human somatic cells or whether additional activities encoded by other...
Shotgun sequencing of the human transcriptome with ORF expressed sequence tags
Dias Neto, Emmanuel, Garcia Correa, Ricardo, Verjovski-Almeida, Sergio, Briones, Marcelo R. S., Nagai, Maria Aparecida, Da Silva, Wilson, ...
Theoretical considerations predict that amplification of expressed gene transcripts by reverse transcription–PCR using arbitrarily chosen primers will result in the preferential amplification of...
The mammary myoepithelial cell - Cinderella or ugly sister?
Lakhani, Sunil R, O'Hare, Michael J
The breast myoepithelial cell is the Cinderella of mammary biology. Although its contribution to benign and some malignant pathologies is recognised, it has been largely neglected in molecular and...
Jongeneel, C. Victor, Iseli, Christian, Stevenson, Brian J., Riggins, Gregory J., Lal, Anita, Mackay, Alan, ...
Whereas information is rapidly accumulating about the structure and position of genes encoded in the human genome, less is known about the complexity and relative abundance of their expression in...
Smith, Patrice D., Crocker, Stephen J., Jackson-Lewis, Vernice, Jordan-Sciutto, Kelly L., Hayley, Shawn, Mount, Matthew P., ...
Recent evidence indicates that cyclin-dependent kinases (CDKs, cdks) may be inappropriately activated in several neurodegenerative conditions. Here, we report that cdk5 expression and activity are...
Models of breast cancer: is merging human and animal models the future?
Kim, Jong B, O'Hare, Michael J, Stein, Robert
Survival rates of patients with early breast cancer in the United Kingdom and in the United States have improved steadily over the past 15 years. The only way to continue or even accelerate this...
Grigoriadis, Anita, Mackay, Alan, Reis-Filho, Jorge S, Steele, Dawn, Iseli, Christian, Stevenson, Brian J, ...
Immortalization of Human Alveolar Epithelial Cells to Investigate Nanoparticle Uptake
Kemp, Sarah J., Thorley, Andrew J., Gorelik, Julia, Seckl, Michael J., O'Hare, Michael J., Arcaro, Alexandre, ...
Primary human alveolar type 2 (AT2) cells were immortalized by transduction with the catalytic subunit of telomerase and simian virus 40 large-tumor antigen. Characterization by immunochemical and...