FEATURE MAPS BASED WEIGHT VECTORS FOR SPATIOTEMPORAL PATTERN RECOGNITION WITH NEURAL NETS (2007)
Matthew M. Yen, Michael R. Blackburn, Hoa G. Nguyen
A neural network algorithm is used to generate the spatial pattern classes for Spatiotemporal Pattern Recog-nition (SPR). This algorithm is known as Kohoncn Feature Maps. Training vectors are...
A GENERAL ARCHITECTURE FOR CLASSICAL CONDITIONING OF PERCEPTUAL-MOTOR SEQUENCES (2007)
A general neural network architecture, loosely modeled on the cerebral cortex, for the classical conditioning of perceptual-motor sequences is described. The utility of such an algorithm in robotics...
In this brief introduction to the topic there are sixteen points that we would like to make in reference to the problems of dynamic scene understanding and 3-D model extraction. We will first list...
Robotic Assisted Search and Rescue (CRASAR) Related Efforts at the World Trade Center (2007)
Michael R. Blackburn, H. R. Everett, Robin T. Laird, T. V. Flynn, Commanding Officer, R. C. Kolb
Approved for public release; distribution is unlimited SSC San Diego
Reichelt, Melissa Elizabeth, Willems, Laura, Peart, Jason Nigel John, Ashton, Kevin John, Matherne, G. Paul, Blackburn, Michael R., ...
Yes
Ashton, Kevin John, Peart, Jason Nigel John, Morrison, R. Ray, Matherne, G. Paul, Blackburn, Michael R., Headrick, John Patrick
Yes
Reichelt, Melissa Elizabeth, Willems, Laura, Peart, Jason Nigel John, Ashton, Kevin John, Matherne, G. Paul, Blackburn, Michael R., ...
Ashton, Kevin John, Peart, Jason Nigel John, Morrison, R. Ray, Matherne, G. Paul, Blackburn, Michael R., Headrick, John Patrick
Reichelt, Melissa Elizabeth, Willems, Laura, Peart, Jason Nigel John, Ashton, Kevin John, Matherne, G. Paul, Blackburn, Michael R., ...
Ashton, Kevin John, Peart, Jason Nigel John, Morrison, R. Ray, Matherne, G. Paul, Blackburn, Michael R., Headrick, John Patrick
Willems, Laura, Reichelt, Melissa Elizabeth, Molina, Jose G, Sun, Chun-Xiao, Chunn, Janci L, Ashton, Kevin John, ...
OBJECTIVE: Adenosine deaminase (ADA) may be multifunctional, regulating adenosine levels and adenosine receptor (AR) agonism, and potentially modifying AR functionality. Herein we assess effects of...
Willems, Laura, Reichelt, Melissa Elizabeth, Molina, Jose G, Sun, Chun-Xiao, Chunn, Janci L, Ashton, Kevin John, ...
OBJECTIVE: Adenosine deaminase (ADA) may be multifunctional, regulating adenosine levels and adenosine receptor (AR) agonism, and potentially modifying AR functionality. Herein we assess effects of...
Willems, Laura, Reichelt, Melissa Elizabeth, Molina, Jose G, Sun, Chun-Xiao, Chunn, Janci L, Ashton, Kevin John, ...
OBJECTIVE: Adenosine deaminase (ADA) may be multifunctional, regulating adenosine levels and adenosine receptor (AR) agonism, and potentially modifying AR functionality. Herein we assess effects of...
Willems, Laura, Reichelt, Melissa Elizabeth, Molina, Jose G, Sun, Chun-Xiao, Chunn, Janci L, Ashton, Kevin John, ...
OBJECTIVE: Adenosine deaminase (ADA) may be multifunctional, regulating adenosine levels and adenosine receptor (AR) agonism, and potentially modifying AR functionality. Herein we assess effects of...
Willems, Laura, Reichelt, Melissa E., Molina, Jose G., Sun, Chun-Xiao, Chunn, Janci L., Ashton, Kevin J., ...
Objective Adenosine deaminase (ADA) may be multifunctional, regulating adenosine levels and adenosine receptor (AR) agonism, and potentially modifying AR functionality. Herein we assess effects of...
Expression of Capacitative Calcium TrpC Proteins in Rat Myometrium During Pregnancy1 (2004)
Lidiya G. Babich, Chun-Ying Ku, Helen Huang, Michael R. Blackburn, Barbara M. Sanborn
External Ca2+ entry into myometrial smooth-muscle cells is important to uterine contraction and hence to labor progression and parturition. Proteins of the transient receptor potential (Trp) channel...
A Simple Method for Range Finding via Laser Triangulation. (1998)
Nguyen, Hoa G., Blackburn, Michael R.
We present the design and implementation of a simple range finder for robotic applications via laser triangulation. The technique does not require knowledge of baseline separation and angles from...
Vision Based Autonomous Robot Navigation: Motion Segmentation, (1998)
Blackburn, Michael R., Nguyen, Hoa G.
The ability to acquire and respond appropriately to targets or obstacles. moving or stationary, while underway, is critical for all unmanned mobile robot applications. This is achieved by most...
Blackburn, Michael R., Everett, H. R., Laird, Robin T.
This report provides a quick summary of the introduction of small teleoperated robots to disaster-related search and rescue operations following the 11 September 2001 terrorist attack upon the World...
Autonomy and Intelligence - A Question of Definitions (1998)
It is tempting to call a mechanism that works by itself autonomous. The common dictionary definition of autonomy supports this temptation. According to Webster's Ninth New College Dictionary,...
Motion Based Target Acquisition and Evaluation in an Adaptive Machine Vision System (1998)
Presented at the Video Photogrammetry and Exploitation Conference, 11-12 May 1995, Washington, D.C.
Autonomous Visual Control of a Mobile Robot (1998)
Blackburn, Michael R., Nguyen, Hoa G.
An autonomous mobile robot with a vision based target acquisition system must be able to find and maintain fixation on a moving target while the system itself is in motion. This capability is...
A General Architecture for Classical Conditioning of Perceptual-Motor Sequences (1998)
A general neural network architecture, loosely modeled on the cerebral cortex, for the classical conditioning of perceptual-motor sequences is described. The utility of such an algorithm in robotics...
Feature Maps Based Weight Vectors for Spatiotemporal Pattern Recognition With Neural Nets (1998)
Yen, Matthew M., Blackburn, Michael R., Nguyen, Hoa G.
A neural network algorithm is used to generate the spatial pattern classes for Spatiotemporal Pattern Recognition (SPR). This algorithm is known as Kohonen Feature Maps. Training vectors are...
Improved Mobility in a Multi Degree of Freedom Unmanned Ground Vehicle (1998)
Blackburn, Michael R., Bailey, Richard, Lytle, Brent
Mandelbrot through his analysis of Fractals (Mandelbrot 1977) has shown that the complexity of the physical geometry of nature is similar at all scales. This implies that a robot of fixed dimension...
Foundations for Learning and Adaptation in a Multi Degree of Freedom Unmanned Ground Vehicle (1998)
Blackburn, Michael R., Bailey, Richard
The real-time coordination and control of a many motion degrees of freedom (dof) unmanned ground vehicle under dynamic conditions in a complex environment is nearly impossible for a human operator to...
A Simple Method for Range Finding via Laser Triangulation (1995)
E Division, Hoa G. Nguyen, Michael R. Blackburn
Introduction: For determining range via triangulation, the baseline distance between source and sensor as well as sensor and source angles are used in theory. Figure 1 shows the configuration for...
Vision based autonomous robot navigation: Motion segmentation. Paper to be presented at the (1995)
Michael R. Blackburn, Hoa G. Nguyen
95RO023 The ability to acquire and respond appropriately to targets or obstacles, moving or stationary, while underway, is critical for all unmanned mobile robot applications. This is achieved by...
Learning in Robot Vision Directed Reaching: A Comparison of Methods (1994)
Michael R. Blackburn, Hoa G. Nguyen
Four neural network algorithms were examined for their ability to adaptively associate stereo camera coordinates with joint positions of a three degree of freedom manipulator arm in a 3D reaching...
Robotic Sensor-Motor Transformations (1994)
Michael R. Blackburn, Hoa G. Nguyen
This paper summarizes work performed at NRaD during FY94 on the integration of robotic sensor and motor systems 1 . Two robotic applications were involved. These are the visual control of a five...
Autonomous visual control of a mobile robot (1994)
Michael R. Blackburn, Hoa G. Nguyen
An autonomous mobile robot with a vision based target acquisition system must be able to find and maintain fixation on a moving target while the system itself is in motion. This capability is...
Biological Model of Vision for an Artificial System that Learns to Perceive Its Enviorament (1989)
Michael R. Blackburn, Hoa G. Nguyen
Abstract: A computer algorithm is described which implements models of the biological visual mechanisms of the retina, thalamic lateral geniculate and perigenieulate nuclei, and primary visual...
Van De Wiele, C. Justin, Vaughn, James G., Blackburn, Michael R., Ledent, Catherine A., Jacobson, Marlene, Jiang, Hong, ...
Thymocyte development past the CD4–CD8– stage is markedly inhibited in adenosine deaminase–deficient (ADA-deficient) murine fetal thymic organ cultures (FTOCs) due to the accumulation of ADA...
Blackburn, Michael R., Lee, Chun G., Young, Hays W.J., Zhu, Zhou, Chunn, Janci L., Kang, Min Jong, ...
IL-13 is an important mediator of inflammation and remodeling. We hypothesized that adenosine accumulation, alterations in adenosine receptors, and adenosine–IL-13 autoinduction are critical events...
Apasov, Sergey G., Blackburn, Michael R., Kellems, Rodney E., Smith, Patrick T., Sitkovsky, Michail V.
Adenosine deaminase (ADA) deficiency in humans results in a severe combined immunodeficiency (SCID). This immunodeficiency is associated with severe disturbances in purine metabolism that are thought...
Thompson, Linda F., Van De Wiele, C. Justin, Laurent, Aletha B., Hooker, Scott W., Vaughn, James G., Jiang, Hong, ...
Murine fetal thymic organ culture was used to investigate the mechanism by which adenosine deaminase (ADA) deficiency causes T-cell immunodeficiency. C57BL/6 fetal thymuses treated with the specific...
A protective role for the A1 adenosine receptor in adenosine-dependent pulmonary injury
Sun, Chun-Xiao, Young, Hays W., Molina, Jose G., Volmer, Jonathan B., Schnermann, Jurgen, Blackburn, Michael R.
Adenosine is a signaling nucleoside that has been implicated in the regulation of asthma and chronic obstructive pulmonary disease. Adenosine signaling can serve both pro- and anti-inflammatory...
Adenosine metabolism and murine strain–specific IL-4–induced inflammation, emphysema, and fibrosis
Ma, Bing, Blackburn, Michael R., Lee, Chun Geun, Homer, Robert J., Liu, Wei, Flavell, Richard A., ...
To define the factors that control the tissue effects of IL-4, we compared the effects of Tg IL-4 in Balb/c and C57BL/6 mice. In the former, IL-4 caused modest eosinophilic inflammation and mild...
Role of A2B adenosine receptor signaling in adenosine-dependent pulmonary inflammation and injury
Sun, Chun-Xiao, Zhong, Hongyan, Mohsenin, Amir, Morschl, Eva, Chunn, Janci L., Molina, Jose G., ...
Adenosine has been implicated in the pathogenesis of chronic lung diseases such as asthma and chronic obstructive pulmonary disease. In vitro studies suggest that activation of the A2B adenosine...
Van De Wiele, C. Justin, Vaughn, James G., Blackburn, Michael R., Ledent, Catherine A., Jacobson, Marlene, Jiang, Hong, ...
Thymocyte development past the CD4–CD8– stage is markedly inhibited in adenosine deaminase–deficient (ADA-deficient) murine fetal thymic organ cultures (FTOCs) due to the accumulation of ADA...
Blackburn, Michael R., Lee, Chun G., Young, Hays W.J., Zhu, Zhou, Chunn, Janci L., Kang, Min Jong, ...
IL-13 is an important mediator of inflammation and remodeling. We hypothesized that adenosine accumulation, alterations in adenosine receptors, and adenosine–IL-13 autoinduction are critical events...
Apasov, Sergey G., Blackburn, Michael R., Kellems, Rodney E., Smith, Patrick T., Sitkovsky, Michail V.
Adenosine deaminase (ADA) deficiency in humans results in a severe combined immunodeficiency (SCID). This immunodeficiency is associated with severe disturbances in purine metabolism that are thought...
Thompson, Linda F., Van De Wiele, C. Justin, Laurent, Aletha B., Hooker, Scott W., Vaughn, James G., Jiang, Hong, ...
Murine fetal thymic organ culture was used to investigate the mechanism by which adenosine deaminase (ADA) deficiency causes T-cell immunodeficiency. C57BL/6 fetal thymuses treated with the specific...
A protective role for the A1 adenosine receptor in adenosine-dependent pulmonary injury
Sun, Chun-Xiao, Young, Hays W., Molina, Jose G., Volmer, Jonathan B., Schnermann, Jurgen, Blackburn, Michael R.
Adenosine is a signaling nucleoside that has been implicated in the regulation of asthma and chronic obstructive pulmonary disease. Adenosine signaling can serve both pro- and anti-inflammatory...
Adenosine metabolism and murine strain–specific IL-4–induced inflammation, emphysema, and fibrosis
Ma, Bing, Blackburn, Michael R., Lee, Chun Geun, Homer, Robert J., Liu, Wei, Flavell, Richard A., ...
To define the factors that control the tissue effects of IL-4, we compared the effects of Tg IL-4 in Balb/c and C57BL/6 mice. In the former, IL-4 caused modest eosinophilic inflammation and mild...
Role of A2B adenosine receptor signaling in adenosine-dependent pulmonary inflammation and injury
Sun, Chun-Xiao, Zhong, Hongyan, Mohsenin, Amir, Morschl, Eva, Chunn, Janci L., Molina, Jose G., ...
Adenosine has been implicated in the pathogenesis of chronic lung diseases such as asthma and chronic obstructive pulmonary disease. In vitro studies suggest that activation of the A2B adenosine...
Mi, Tiejuan, Abbasi, Shahrzad, Zhang, Hong, Uray, Karen, Chunn, Janci L., Xia, Ling Wei, ...
Priapism, abnormally prolonged penile erection in the absence of sexual excitation, is associated with ischemia-mediated erectile tissue damage and subsequent erectile dysfunction. It is common among...
Blackburn, Michael R., Volmer, Jonathan B., Thrasher, Janci L., Zhong, Hongyan, Crosby, Jeff R., Lee, James J., ...
Adenosine deaminase (ADA) is a purine catabolic enzyme that manages levels of the biologically active purines adenosine and 2′-deoxyadenosine in tissues and cells. ADA-deficient mice die at 3 wk of...
Central Role of Muc5ac Expression in Mucous Metaplasia and Its Regulation by Conserved 5′ Elements
Young, Hays W. J., Williams, Olatunji W., Chandra, Divay, Bellinghausen, Lindsey K., Pérez, Guillermina, Suárez, Alberto, ...
Mucus hypersecretion contributes to morbidity and mortality in many obstructive lung diseases. Gel-forming mucins are the chief glycoprotein components of airway mucus, and elevated expression of...
Csóka, Balázs, Németh, Zoltán H., Virág, László, Gergely, Pál, Leibovich, S. Joseph, Pacher, Pál, ...
We recently showed that A2A adenosine receptor activation by endogenous adenosine contributes to interleukin-10 (IL-10) production in polymicrobial sepsis. Here we investigated the molecular...
Fernández, Patricia, Trzaska, Sean, Wilder, Tuere, Chiriboga, Luis, Blackburn, Michael R., Cronstein, Bruce N., ...
Adenosine is a potent modulator of inflammation and tissue repair. We have recently reported that activation of adenosine A2A receptors promotes collagen synthesis by human dermal fibroblasts and...
Disease-Specific Gene Expression Profiling in Multiple Models of Lung Disease
Lewis, Christina C., Yang, Jean Yee Hwa, Huang, Xiaozhu, Banerjee, Suman K., Blackburn, Michael R., Baluk, Peter, ...
Rationale: Microarray technology is widely employed for studying the molecular mechanisms underlying complex diseases. However, analyses of individual diseases or models of diseases frequently yield...
A3 Adenosine Receptor Signaling Contributes to Airway Mucin Secretion after Allergen Challenge
Young, Hays W. J., Sun, Chun-Xiao, Evans, Christopher M., Dickey, Burton F., Blackburn, Michael R.
Mucin hypersecretion is a prominent feature of obstructive airway diseases such as asthma. Clara cells conditionally produce mucin in response to inflammatory signals in a process termed mucous...
Adenosine signaling contributes to ethanol-induced fatty liver in mice
Peng, Zhongsheng, Borea, Pier Andrea, Wilder, Tuere, Yee, Herman, Chiriboga, Luis, Blackburn, Michael R., ...
Fatty liver is commonly associated with alcohol ingestion and abuse. While the molecular pathogenesis of these fatty changes is well understood, the biochemical and pharmacological mechanisms by...
Adenosine signaling contributes to ethanol-induced fatty liver in mice
Peng, Zhongsheng, Borea, Pier Andrea, Wilder, Tuere, Yee, Herman, Chiriboga, Luis, Blackburn, Michael R., ...
Zhai, Yuxin, Zhong, Zhenping, Chen, Chyi-Ying A., Xia, Zhenfang, Song, Ling, Blackburn, Michael R., ...
Bronchial epithelial cells play a pivotal role in airway inflammation, but little is known about posttranscriptional regulation of mediator gene expression during the inflammatory response in these...
Adenosine receptors in regulation of dendritic cell differentiation and function
Novitskiy, Sergey V., Ryzhov, Sergey, Zaynagetdinov, Rinat, Goldstein, Anna E., Huang, Yuhui, Tikhomirov, Oleg Y., ...
Differentiation of functional dendritic cells (DCs) critically depends on the microenvironment. DCs differentiate in hypoxic tumor sites and inflamed or damaged tissue. Because local concentrations...