Graph theoretical approach to study eQTL: a case study of Plasmodium falciparum (2009)
Huang, Yang, Wuchty, Stefan, Ferdig, Michael T., Przytycka, Teresa M.
Motivation: Analysis of expression quantitative trait loci (eQTL) significantly contributes to the determination of gene regulation programs. However, the discovery and analysis of associations of...
Regulatory Hotspots in the Malaria Parasite Genome Dictate Transcriptional Variation (2008)
Joseph M. Gonzales, Jigar J. Patel, Napawan Ponmee, Lei Jiang, Asako Tan, Steven P. Maher, ...
The determinants of transcriptional regulation in malaria parasites remain elusive. The presence of a well-characterized gene expression cascade shared by different Plasmodium falciparum strains...
Jiang, Hongying, Patel, Jigar J., Yi, Ming, Mu, Jianbing, Ding, Jinhui, Stephens, Robert, ...
Mutations in PfCRT (Plasmodium falciparum chloroquine-resistant transporter), particularly the substitution at amino acid position 76, confer chloroquine (CQ) resistance in P. falciparum. Point...
Stable evolutionary signal in a Yeast protein interaction network (2006)
Wuchty, Stefan, Barabási, Albert-Laszlo, Ferdig, Michael T
Abstract Background The recently emerged protein interaction network paradigm can provide novel and important insights into the innerworkings of a cell. Yet, the heavy burden of both false positive...
Thesis (M.S.)--University of Nebraska--Lincoln, 1990.
Genetic linkage of pfmdr1 with food vacuolar solute import in Plasmodium falciparum
Rohrbach, Petra, Sanchez, Cecilia P, Hayton, Karen, Friedrich, Oliver, Patel, Jigar, Sidhu, Amar Bir Singh, ...
The P-glycoprotein homolog of the human malaria parasite Plasmodium falciparum (Pgh-1) has been implicated in decreased susceptibility to several antimalarial drugs, including quinine, mefloquine and...
Jiang, Hongying, Patel, Jigar J., Yi, Ming, Mu, Jianbing, Ding, Jinhui, Stephens, Robert, ...
Mutations in PfCRT (Plasmodium falciparum chloroquine-resistant transporter), particularly the substitution at amino acid position 76, confer chloroquine (CQ) resistance in P. falciparum. Point...
Regulatory Hotspots in the Malaria Parasite Genome Dictate Transcriptional Variation
Gonzales, Joseph M, Patel, Jigar J, Ponmee, Napawan, Jiang, Lei, Tan, Asako, Maher, Steven P, ...
The determinants of transcriptional regulation in malaria parasites remain elusive. The presence of a well-characterized gene expression cascade shared by different Plasmodium falciparum strains...
Adaptive Copy Number Evolution in Malaria Parasites
Nair, Shalini, Miller, Becky, Barends, Marion, Jaidee, Anchalee, Patel, Jigar, Mayxay, Mayfong, ...
Copy number polymorphism (CNP) is ubiquitous in eukaryotic genomes, but the degree to which this reflects the action of positive selection is poorly understood. The first gene in the Plasmodium...
Graph theoretical approach to study eQTL: a case study of Plasmodium falciparum
Huang, Yang, Wuchty, Stefan, Ferdig, Michael T., Przytycka, Teresa M.
Motivation: Analysis of expression quantitative trait loci (eQTL) significantly contributes to the determination of gene regulation programs. However, the discovery and analysis of associations of...