Michael W. SMITH

Association of APOEpolymorphism with chronic kidney disease in a nationally representative sample: a Third National Health and Nutrition Examination Survey (NHANES III) Genetic Study (2009)

Chu, Audrey Y, Parekh, Rulan S, Astor, Brad C, Coresh, Josef, Berthier-Schaad, Yvette, Smith, Michael W, ...

Abstract Background Apolipoprotein E polymorphisms ( APOE ) have been associated with lowered glomerular filtration rate (GFR) and chronic kidney disease (CKD) with e2 allele conferring risk and e4...

Genome and gene alterations by insertions and deletions in the evolution of human and chimpanzee chromosome 22 (2009)

Volfovsky, Natalia, Oleksyk, Taras K, Cruz, Kristine C, Truelove, Ann L, Stephens, Robert M, Smith, Michael W

Abstract Background Understanding structure and function of human genome requires knowledge of genomes of our closest living relatives, the primates. Nucleotide insertions and deletions (indels) play...

Hypothesis-Driven Candidate Gene Association Studies: Practical Design and Analytical Considerations (2009)

Jorgensen, Timothy J., Ruczinski, Ingo, Kessing, Bailey, Smith, Michael W., Shugart, Yin Yao, Alberg, Anthony J.

Candidate gene association studies (CGAS) are a useful epidemiologic approach to drawing inferences about relations between genes and disease, especially when experimental data support the...

DISEQUILIBRIUM: ADVANCES, LIMITATIONS AND GUIDELINES (2005)

Michael W. Smith, Stephen J. O’brien

A method for localizing genes that is based on the co-inheritance of genetic markers and phenotypes in families over several generations. ASSOCIATION STUDIES A gene-discovery strategy that compares...

Sodium balance in feeder steers. (1974)

Smith, Michael W.

Thesis (M.S.)--Texas Tech University, 1974.

Identifying Selected Regions from Heterozygosity and Divergence Using a Light-Coverage Genomic Dataset from Two Human Populations

Oleksyk, Taras K., Zhao, Kai, De La Vega, Francisco M., Gilbert, Dennis A., O'Brien, Stephen J., Smith, Michael W.

When a selective sweep occurs in the chromosomal region around a target gene in two populations that have recently separated, it produces three dramatic genomic consequences: 1) decreased multi-locus...