Michaela Rohrmoser

Analyse des PeBoW-Komplexes in der Ribosomenbiogenese (2008)

Rohrmoser, Michaela

Während der Zellproliferation müssen Zellwachstum und Zellteilung koordiniert werden. Die Kopplung erfolgt in der Hefe durch einen Komplex aus Nop7p, Erb1p und Ytm1p, der sowohl an der...

Analyse des PeBoW-Komplexes in der Ribosomenbiogenese (2008)

Rohrmoser, Michaela

Während der Zellproliferation müssen Zellwachstum und Zellteilung koordiniert werden. Die Kopplung erfolgt in der Hefe durch einen Komplex aus Nop7p, Erb1p und Ytm1p, der sowohl an der...

The BRCT domain of mammalian Pes1 is crucial for nucleolar localization and rRNA processing (2007)

Hölzel, Michael, Grimm, Thomas, Rohrmoser, Michaela, Malamoussi, Anastassia, Harasim, Thomas, Gruber-Eber, Anita, ...

The nucleolar protein Pes1 interacts with Bop1 and WDR12 in a stable complex (PeBoW-complex) and its expression is tightly associated with cell proliferation. The yeast homologue Nop7p (Yph1p)...

Rapid conditional knock-down-knock-in system for mammalian cells (2007)

Hölzel, Michael, Rohrmoser, Michaela, Orban, Mathias, Hömig, Cornelia, Harasim, Thomas, Malamoussi, Anastassia, ...

RNA interference (RNAi) is a powerful tool to analyze gene function in mammalian cells. However, the interpretation of RNAi knock-down phenotypes can be hampered by off-target effects or compound...

Dominant-negative Pes1 mutants inhibit ribosomal RNA processing and cell proliferation via incorporation into the PeBoW-complex (2006)

Grimm, Thomas, Hölzel, Michael, Rohrmoser, Michaela, Harasim, Thomas, Malamoussi, Anastassia, Gruber-Eber, Anita, ...

The nucleolar PeBoW-complex, consisting of Pes1, Bop1 and WDR12, is essential for cell proliferation and processing of ribosomal RNA in mammalian cells. Here we have analysed the physical and...

Rapid conditional knock-down-knock-in system for mammalian cells (2006)

Hölzel, Michael, Rohrmoser, Michaela, Orban, Mathias, Hömig, Cornelia, Harasim, Thomas, Malamoussi, Anastassia, ...

RNA interference (RNAi) is a powerful tool to analyze gene function in mammalian cells. However, the interpretation of RNAi knock-down phenotypes can be hampered by off-target effects or compound...

The BRCT domain of mammalian Pes1 is crucial for nucleolar localization and rRNA processing (2006)

Hölzel, Michael, Grimm, Thomas, Rohrmoser, Michaela, Malamoussi, Anastassia, Harasim, Thomas, Gruber-Eber, Anita, ...

The nucleolar protein Pes1 interacts with Bop1 and WDR12 in a stable complex (PeBoW-complex) and its expression is tightly associated with cell proliferation. The yeast homologue Nop7p (Yph1p)...

Rapid conditional knock-down-knock-in system for mammalian cells (2006)

Hölzel, Michael, Rohrmoser, Michaela, Orban, Mathias, Hömig, Cornelia, Harasim, Thomas, Malamoussi, Anastassia, ...

RNA interference (RNAi) is a powerful tool to analyze gene function in mammalian cells. However, the interpretation of RNAi knock-down phenotypes can be hampered by off-target effects or compound...

The BRCT domain of mammalian Pes1 is crucial for nucleolar localization and rRNA processing (2006)

Hölzel, Michael, Grimm, Thomas, Rohrmoser, Michaela, Malamoussi, Anastassia, Harasim, Thomas, Gruber-Eber, Anita, ...

The nucleolar protein Pes1 interacts with Bop1 and WDR12 in a stable complex (PeBoW-complex) and its expression is tightly associated with cell proliferation. The yeast homologue Nop7p (Yph1p)...

HybF, a zinc-containing protein involved in NiFe hydrogenase maturation. (2004)

Blokesch, Melanie, Rohrmoser, Michaela, Rode, Sabine, Böck, August

HypA and HypB are maturation proteins required for incorporation of nickel into the hydrogenase large subunit. To examine the functions of these proteins in nickel insertion, the hybF gene, which is...

HybF, a Zinc-Containing Protein Involved in NiFe Hydrogenase Maturation

Blokesch, Melanie, Rohrmoser, Michaela, Rode, Sabine, Böck, August

HypA and HypB are maturation proteins required for incorporation of nickel into the hydrogenase large subunit. To examine the functions of these proteins in nickel insertion, the hybF gene, which is...

Dominant-negative Pes1 mutants inhibit ribosomal RNA processing and cell proliferation via incorporation into the PeBoW-complex

Grimm, Thomas, Hölzel, Michael, Rohrmoser, Michaela, Harasim, Thomas, Malamoussi, Anastassia, Gruber-Eber, Anita, ...

The nucleolar PeBoW-complex, consisting of Pes1, Bop1 and WDR12, is essential for cell proliferation and processing of ribosomal RNA in mammalian cells. Here we have analysed the physical and...

HybF, a Zinc-Containing Protein Involved in NiFe Hydrogenase Maturation

Blokesch, Melanie, Rohrmoser, Michaela, Rode, Sabine, Böck, August

HypA and HypB are maturation proteins required for incorporation of nickel into the hydrogenase large subunit. To examine the functions of these proteins in nickel insertion, the hybF gene, which is...

Dominant-negative Pes1 mutants inhibit ribosomal RNA processing and cell proliferation via incorporation into the PeBoW-complex

Grimm, Thomas, Hölzel, Michael, Rohrmoser, Michaela, Harasim, Thomas, Malamoussi, Anastassia, Gruber-Eber, Anita, ...

The nucleolar PeBoW-complex, consisting of Pes1, Bop1 and WDR12, is essential for cell proliferation and processing of ribosomal RNA in mammalian cells. Here we have analysed the physical and...

Rapid conditional knock-down–knock-in system for mammalian cells

Hölzel, Michael, Rohrmoser, Michaela, Orban, Mathias, Hömig, Cornelia, Harasim, Thomas, Malamoussi, Anastassia, ...

RNA interference (RNAi) is a powerful tool to analyze gene function in mammalian cells. However, the interpretation of RNAi knock-down phenotypes can be hampered by off-target effects or compound...

The BRCT domain of mammalian Pes1 is crucial for nucleolar localization and rRNA processing

Hölzel, Michael, Grimm, Thomas, Rohrmoser, Michaela, Malamoussi, Anastassia, Harasim, Thomas, Gruber-Eber, Anita, ...

The nucleolar protein Pes1 interacts with Bop1 and WDR12 in a stable complex (PeBoW-complex) and its expression is tightly associated with cell proliferation. The yeast homologue Nop7p (Yph1p)...

Interdependence of Pes1, Bop1, and WDR12 Controls Nucleolar Localization and Assembly of the PeBoW Complex Required for Maturation of the 60S Ribosomal Subunit▿

Rohrmoser, Michaela, Hölzel, Michael, Grimm, Thomas, Malamoussi, Anastassia, Harasim, Thomas, Orban, Mathias, ...

The PeBoW complex is essential for cell proliferation and maturation of the large ribosomal subunit in mammalian cells. Here we examined the role of PeBoW-specific proteins Pes1, Bop1, and WDR12 in...

Mammalian WDR12 is a novel member of the Pes1–Bop1 complex and is required for ribosome biogenesis and cell proliferation

Hölzel, Michael, Rohrmoser, Michaela, Schlee, Martin, Grimm, Thomas, Harasim, Thomas, Malamoussi, Anastassia, ...

Target genes of the protooncogene c-myc are implicated in cell cycle and growth control, yet the linkage of both is still unexplored. Here, we show that the products of the nucleolar target genes...