Long-Term Recording of LTP in Cultured Hippocampal Slices (2002)
Ken Shimono, Michel Baudry, Lam Ho, Makoto Taketani, Gary Lynch
Long-term potentiation (LTP) was elicited by high frequency stimulation in hippocampal slices cultured on multi-electrode arrays. LTP lasting more than 1 h was recorded in 75% of slices, and a...
Sensing of Neuron Signals Using Microelectromechanical Systems (1998)
Baudry, Michel, Berger, Theodore W., Kim, Eun Sok, McKenna, Charles E., Thompson, Mark E.
The goal of our program was to access the viability of using MEMS devices to detect tiring signatures from neurons. In order to evaluate these devices we needed to prepare and test MEMS devices...
Maren, Stephen, Baudry, Michel
Long-term potentiation (LTP) in the hippocampus and long-term depression (LTD) in the cerebellum are two forms of long-lasting synaptic plasticity that currently serve as our primary experimental...
Maren, Stephen, Tocco, Georges, Chavanne, Frederic, Baudry, Michel, Thompson, Richard F., Mitchell, Denis
Previous work from our laboratory indicated that emergence neophobia is highly correlated with perforant path long-term potentiation (LTP) in rats. In the present study, we examined the relationship...
Maren, Stephen, Tocco, Georges, Standley, Steven, Baudry, Michel, Thompson, Richard F.
Several lines of evidence indicate that LTP in the hippocampus is associated with a change in the properties of postsynaptic glutamate receptors. In the present study, we used quantitative...
Maren, Stephen, Baudry, Michel, Thompson, Richard F.
The effects of the novel competitive N-methyl-D-aspartate (NMDA) receptor antagonist, CGP 39551 [the carboxyethylester of CGP 37849; DL-(E)-2-amino-4-methyl-5-phosphono-3-pentenoic acid], on...
Long-term potentiation is associated with increased [3H]AMPA binding in rat hippocampus (1992)
Tocco, Georges, Maren, Stephen, Shors, Tracey J., Baudry, Michel, Thompson, Richard F.
The location and nature of the changes underlying long-term potentiation (LTP) remain controversial issues. In this study, we tested the possibility that changes in binding properties of the...
Differential effects of ketamine and MK-801 on the induction of long-term potentiation (1991)
Maren, Stephen, Baudry, Michel, Thompson, Richard F.
Ketamine and MK-801 are phencyclidine (PCP)-like noncompetitive antagonists of the N-methyl-D-aspartate (NMDA) receptor that produce a use-dependent blockade of the NMDA receptor-coupled channel....
Multigraphié.
Bi, Ruifen, Broutman, Greg, Foy, Mike R., Thompson, Richard F., Baudry, Michel
Estrogen replacement therapy in women is associated with improvement of cognitive deficits and reduced incidence of Alzheimer's disease. The present study indicates that estrogen is neuroprotective...
Xie, Xiaping, Liaw, Jim-Shih, Baudry, Michel, Berger, Theodore W.
A combination of experimental and modeling approaches was used to study cellular–molecular mechanisms underlying the expression of short-term potentiation (STP) and long-term potentiation (LTP) of...
Rong, Yongqi, Doctrow, Susan R., Tocco, Georges, Baudry, Michel
The present study tested the effects of EUK-134, a synthetic superoxide dismutase/catalase mimetic, on several indices of oxidative stress and neuropathology produced in the rat limbic system as a...
Musleh, Wael, Bi, Xiaoning, Tocco, Georges, Yaghoubi, Shahriar, Baudry, Michel
Global long-term potentiation (LTP) was induced in organotypic hippocampal slice cultures by a brief application of 10 mM glycine. Glycine-induced LTP was occluded by previous theta burst...
Cyclic changes in estradiol regulate synaptic plasticity through the MAP kinase pathway
Bi, Ruifen, Foy, Michael R., Vouimba, Rose-Marie, Thompson, Richard F., Baudry, Michel
Hippocampal synaptic structure and function exhibit marked variations during the estrus cycle of female rats. Estradiol activates the mitogen-activated protein (MAP) kinase pathway in numerous cell...
Liu, Ruolan, Liu, Ingrid Y., Bi, Xiaoning, Thompson, Richard F., Doctrow, Susan R., Malfroy, Bernard, ...
Oxidative stress has been implicated in cognitive impairment in both old experimental animals and aged humans. This implication has led to the notion that antioxidant defense mechanisms in the brain...
Bi, Ruifen, Broutman, Greg, Foy, Mike R., Thompson, Richard F., Baudry, Michel
Estrogen replacement therapy in women is associated with improvement of cognitive deficits and reduced incidence of Alzheimer's disease. The present study indicates that estrogen is neuroprotective...
Xie, Xiaping, Liaw, Jim-Shih, Baudry, Michel, Berger, Theodore W.
A combination of experimental and modeling approaches was used to study cellular–molecular mechanisms underlying the expression of short-term potentiation (STP) and long-term potentiation (LTP) of...
Rong, Yongqi, Doctrow, Susan R., Tocco, Georges, Baudry, Michel
The present study tested the effects of EUK-134, a synthetic superoxide dismutase/catalase mimetic, on several indices of oxidative stress and neuropathology produced in the rat limbic system as a...
Musleh, Wael, Bi, Xiaoning, Tocco, Georges, Yaghoubi, Shahriar, Baudry, Michel
Global long-term potentiation (LTP) was induced in organotypic hippocampal slice cultures by a brief application of 10 mM glycine. Glycine-induced LTP was occluded by previous theta burst...
Cyclic changes in estradiol regulate synaptic plasticity through the MAP kinase pathway
Bi, Ruifen, Foy, Michael R., Vouimba, Rose-Marie, Thompson, Richard F., Baudry, Michel
Hippocampal synaptic structure and function exhibit marked variations during the estrus cycle of female rats. Estradiol activates the mitogen-activated protein (MAP) kinase pathway in numerous cell...
Liu, Ruolan, Liu, Ingrid Y., Bi, Xiaoning, Thompson, Richard F., Doctrow, Susan R., Malfroy, Bernard, ...
Oxidative stress has been implicated in cognitive impairment in both old experimental animals and aged humans. This implication has led to the notion that antioxidant defense mechanisms in the brain...
Bi, Xiaoning, Liu, Jihua, Yao, Yueqin, Baudry, Michel, Lynch, Gary
Niemann-Pick type C (NPC) disease is caused by mutations to genes that encode proteins critical to intracellular lipid homeostasis. The events underlying NPC progressive neurodegeneration are poorly...
Long-Term Recording of LTP in Cultured Hippocampal Slices
Shimono, Ken, Baudry, Michel, Ho, Lam, Taketani, Makoto, Lynch, Gary
Long-term potentiation (LTP) was elicited by high frequency stimulation in hippocampal slices cultured on multi-electrode arrays. LTP lasting more than 1 h was recorded in 75% of slices, and a...