Olivier Garcia, Cosmin Saveanu, Melissa Cline, Micheline Fromont-racine, Alain Jacquier, Benno Schwikowski, ...
Summary: We have implemented a graph layout algorithm that exposes Gene Ontology (GO) class structure on the network nodes. It can be used in conjunction with BiNGO plug-in to Cytoscape, which finds...
Lebreton, Alice, Rousselle, Jean-Claude, Lenormand, Pascal, Namane, Abdelkader, Jacquier, Alain, Fromont-Racine, Micheline, ...
During the highly conserved process of eukaryotic ribosome formation, RNA follows a maturation path with well-defined, successive intermediates that dynamically associate with many pre-ribosomal...
Demoinet, Emilie, Jacquier, Alain, Lutfalla, Georges, Fromont-Racine, Micheline
Ribosome biogenesis is a major conserved cellular pathway that requires both ribosomal proteins and many preribosomal factors. Most of the pre-60S factors are recycled into the nucleus; some of them...
Cytoplasmic Recycling of 60S Preribosomal Factors Depends on the AAA Protein Drg1 (2007)
Pertschy, Brigitte, Saveanu, Cosmin, Zisser, Gertrude, Lebreton, Alice, Tengg, Martin, Jacquier, Alain, ...
Allelic forms of DRG1/AFG2 confer resistance to the drug diazaborine, an inhibitor of ribosome biogenesis in Saccharomyces cerevisiae. Our results show that the AAA-ATPase Drg1 is essential for 60S...
Garcia, Olivier, Saveanu, Cosmin, Cline, Melissa, Fromont-Racine, Micheline, Jacquier, Alain, Schwikowski, Benno, ...
Summary: We have implemented a graph layout algorithm that exposes Gene Ontology (GO) class structure on the network nodes. It can be used in conjunction with BiNGO plug-in to Cytoscape, which finds...
Gene Ontology-based layout and coloring (2006)
Olivier Garcia, Cosmin Saveanu, Melissa Cline, Micheline Fromont-racine, Alain Jacquier, Benno Schwikowski, ...
doi:10.1093/bioinformatics/btl605 GOlorize: a Cytoscape plug-in for network visualization with
BADIS, GWENAEL, FROMONT-RACINE, MICHELINE, JACQUIER, ALAIN
Ribosomal RNAs contain a number of modified nucleotides. The most abundant nucleotide modifications found within rRNAs fall into two types: 2′-O-ribose methylations and pseudouridylations. In...
Genome-Wide Protein Interaction Screens Reveal Functional Networks Involving Sm-Like Proteins (2000)
Micheline Fromont-Racine, Andrew E. Mayes, Adeline Brunet-Simon, Jean-Christophe Rain, Alan Colley, Ian Dix, ...
A set of seven structurally related Sm proteins forms the core of the snRNP particles containing the spliceosomal U1, U2, U4 and U5 snRNAs. A search of the genomic sequence of Saccharomyces...
A highly sensitive method for mapping the 5' termini of mRNAs (1993)
Fromont-Racine, Micheline, Bertrand, Edouard, Pictet, Raymond, Grange, Thierry
Parallel analysis of genetic selections using whole genome oligonucleotide arrays
Cho, Raymond J., Fromont-Racine, Micheline, Wodicka, Lisa, Feierbach, Becket, Stearns, Timothy, Legrain, Pierre, ...
Thousands of genes have recently been sequenced in organisms ranging from Escherichia coli to human. For the majority of these genes, however, available sequence does not define a biological role....
Nog2p, a putative GTPase associated with pre-60S subunits and required for late 60S maturation steps
Saveanu, Cosmin, Bienvenu, David, Namane, Abdelkader, Gleizes, Pierre-Emmanuel, Gas, Nicole, Jacquier, Alain, ...
Eukaryotic ribosome maturation depends on a set of well ordered processing steps. Here we describe the functional characterization of yeast Nog2p (Ynr053cp), a highly conserved nuclear protein. Nog2p...
Sequential Protein Association with Nascent 60S Ribosomal Particles
Saveanu, Cosmin, Namane, Abdelkader, Gleizes, Pierre-Emmanuel, Lebreton, Alice, Rousselle, Jean-Claude, Noaillac-Depeyre, Jacqueline, ...
Ribosome biogenesis in eukaryotes depends on the coordinated action of ribosomal and nonribosomal proteins that guide the assembly of preribosomal particles. These intermediate particles follow a...
The Splicing ATPase Prp43p Is a Component of Multiple Preribosomal Particles
Lebaron, Simon, Froment, Carine, Fromont-Racine, Micheline, Rain, Jean-Christophe, Monsarrat, Bernard, Caizergues-Ferrer, Michèle, ...
Prp43p is a putative helicase of the DEAH family which is required for the release of the lariat intron from the spliceosome. Prp43p could also play a role in ribosome synthesis, since it accumulates...
BADIS, GWENAEL, FROMONT-RACINE, MICHELINE, JACQUIER, ALAIN
Ribosomal RNAs contain a number of modified nucleotides. The most abundant nucleotide modifications found within rRNAs fall into two types: 2′-O-ribose methylations and pseudouridylations. In...
Parallel analysis of genetic selections using whole genome oligonucleotide arrays
Cho, Raymond J., Fromont-Racine, Micheline, Wodicka, Lisa, Feierbach, Becket, Stearns, Timothy, Legrain, Pierre, ...
Thousands of genes have recently been sequenced in organisms ranging from Escherichia coli to human. For the majority of these genes, however, available sequence does not define a biological role....
Nog2p, a putative GTPase associated with pre-60S subunits and required for late 60S maturation steps
Saveanu, Cosmin, Bienvenu, David, Namane, Abdelkader, Gleizes, Pierre-Emmanuel, Gas, Nicole, Jacquier, Alain, ...
Eukaryotic ribosome maturation depends on a set of well ordered processing steps. Here we describe the functional characterization of yeast Nog2p (Ynr053cp), a highly conserved nuclear protein. Nog2p...
Sequential Protein Association with Nascent 60S Ribosomal Particles
Saveanu, Cosmin, Namane, Abdelkader, Gleizes, Pierre-Emmanuel, Lebreton, Alice, Rousselle, Jean-Claude, Noaillac-Depeyre, Jacqueline, ...
Ribosome biogenesis in eukaryotes depends on the coordinated action of ribosomal and nonribosomal proteins that guide the assembly of preribosomal particles. These intermediate particles follow a...
The Splicing ATPase Prp43p Is a Component of Multiple Preribosomal Particles
Lebaron, Simon, Froment, Carine, Fromont-Racine, Micheline, Rain, Jean-Christophe, Monsarrat, Bernard, Caizergues-Ferrer, Michèle, ...
Prp43p is a putative helicase of the DEAH family which is required for the release of the lariat intron from the spliceosome. Prp43p could also play a role in ribosome synthesis, since it accumulates...
BADIS, GWENAEL, FROMONT-RACINE, MICHELINE, JACQUIER, ALAIN
Ribosomal RNAs contain a number of modified nucleotides. The most abundant nucleotide modifications found within rRNAs fall into two types: 2′-O-ribose methylations and pseudouridylations. In...
Saveanu, Cosmin, Rousselle, Jean-Claude, Lenormand, Pascal, Namane, Abdelkader, Jacquier, Alain, Fromont-Racine, Micheline
Ribosome biogenesis is driven by a large number of preribosomal factors that associate with and dissociate from the preribosomal particles along the maturation pathway. We have previously shown that...
A functional network involved in the recycling of nucleocytoplasmic pre-60S factors
Lebreton, Alice, Saveanu, Cosmin, Decourty, Laurence, Rain, Jean-Christophe, Jacquier, Alain, Fromont-Racine, Micheline
Eukaryotic pre-ribosomes go through cytoplasmic maturation steps before entering translation. The nucleocytoplasmic proteins participating in these late stages of maturation are reimported to the...
Cytoplasmic Recycling of 60S Preribosomal Factors Depends on the AAA Protein Drg1▿ †
Pertschy, Brigitte, Saveanu, Cosmin, Zisser, Gertrude, Lebreton, Alice, Tengg, Martin, Jacquier, Alain, ...
Allelic forms of DRG1/AFG2 confer resistance to the drug diazaborine, an inhibitor of ribosome biogenesis in Saccharomyces cerevisiae. Our results show that the AAA-ATPase Drg1 is essential for 60S...
Demoinet, Emilie, Jacquier, Alain, Lutfalla, Georges, Fromont-Racine, Micheline
Ribosome biogenesis is a major conserved cellular pathway that requires both ribosomal proteins and many preribosomal factors. Most of the pre-60S factors are recycled into the nucleus; some of them...
Belgareh, Naïma, Rabut, Gwénaël, Baï, Siau Wei, Van Overbeek, Megan, Beaudouin, Joël, Daigle, Nathalie, ...
The nuclear pore complexes (NPCs) are evolutionarily conserved assemblies that allow traffic between the cytoplasm and the nucleus. In this study, we have identified and characterized a novel human...
Genome-Wide Protein Interaction Screens Reveal Functional Networks Involving Sm-Like Proteins
Fromont-Racine, Micheline, Mayes, Andrew E., Brunet-Simon, Adeline, Rain, Jean-Christophe, Colley, Alan, Dix, Ian, ...
A set of seven structurally related Sm proteins forms the core of the snRNP particles containing the spliceosomal U1, U2, U4 and U5 snRNAs. A search of the genomic sequence of Saccharomyces...
Lebreton, Alice, Rousselle, Jean-Claude, Lenormand, Pascal, Namane, Abdelkader, Jacquier, Alain, Fromont-Racine, Micheline, ...
During the highly conserved process of eukaryotic ribosome formation, RNA follows a maturation path with well-defined, successive intermediates that dynamically associate with many pre-ribosomal...
Decourty, Laurence, Saveanu, Cosmin, Zemam, Kenza, Hantraye, Florence, Frachon, Emmanuel, Rousselle, Jean-Claude, ...
Describing at a genomic scale how mutations in different genes influence one another is essential to the understanding of how genotype correlates with phenotype and remains a major challenge in...