Michelle Rudolph

Frequency-selectivity of a thalamocortical relay neuron during Parkinson's disease and deep brain stimulation: a computational study (2009)

Cagnan, Hayriye, Meijer, Hil G.E., Gils Van, Stephan A., Krupa, Martin, Heida, Tjitske, Rudolph, Michelle, ...

In this computational study, we investigated (i) the functional importance of correlated basal ganglia (BG) activity associated with Parkinson's disease (PD) motor symptoms by analysing the effects...

J Comput Neurosci DOI 10.1007/s10827-007-0038-6 TOPICAL REVIEW ON TECHNIQUES Simulation of networks of spiking neurons: A review of tools and strategies (2008)

Romain Brette, Michelle Rudolph, Ted Carnevale, Michael Hines, David Beeman, James M. Bower, ...

Abstract We review different aspects of the simulation of spiking neural networks. We start by reviewing the different types of simulation strategies and algorithms that are currently implemented. We...

Inhibition determines membrane potential dynamics and controls action potential generation in awake and sleeping cat cortex (2007)

Michelle Rudolph, Martin Pospischil, Igor Timofeev, Alain Destexhe

Intracellular recordings of cortical neurons in awake cat and monkey show a depolarized state, sustained firing, and intense subthreshold synaptic activity. It is not known what conductance dynamics...

Simulation of networks of spiking neurons: A review of tools and strategies (2007)

Romain Brette, Michelle Rudolph, Ted Carnevale, Michael Hines, David Beeman, James M. Bower, ...

We review different aspects of the simulation of spiking neural networks. We start by reviewing the different types of simulation strategies and algorithms that are currently implemented. We next...

Calculating event-triggered average synaptic conductances from the membrane potential (2006)

Pospischil, Martin, Piwkowska, Zuzanna, Rudolph, Michelle, Bal, Thierry, Destexhe, Alain

The optimal patterns of synaptic conductances for spike generation in central neurons is a subject of considerable interest. Ideally, such conductance time courses should be extracted from membrane...

On the use of analytic expressions for the voltage distribution to analyze intracellular recordings (2006)

Rudolph, Michelle, Destexhe, Alain

Different analytic expressions for the membrane potential distribution of membranes subject to synaptic noise have been proposed, and can be very helpful to analyze experimental data. However, all of...

How much can we trust neural simulation strategies? (2006)

Michelle Rudolph, Alain Destexhe

Despite a steady improvement of computational hardware, results of numerical simulation are still tightly bound to the simulation tool and strategy used, and may substantially vary across available...

Inhibitory conductance dynamics in cortical neurons during activated states $ (2006)

Martin Pospischil, Zuzanna Piwkowska, Michelle Rudolph, Thierry Bal, Alain Destexhe

During activated states in vivo, neocortical neurons are subject to intense synaptic activity and high-amplitude membrane potential ðVmÞ fluctuations. These ‘‘high-conductance’ ’ states may...