Lopes, Susana, Lewis, Annabelle, Hajkova, Petra, Dean, Wendy, Oswald, Joachim, Forné, Thierry, ...
Imprinted genes and their control elements occur in clusters in the mammalian genome and carry epigenetic modifications. Observations from imprinting disorders suggest that epigenetic modifications...
Placental-specific IGF-II is a major modulator of placental and fetal growth (2002)
Constância,Miguel, Hemberger,Myriam, Hughes,Jennifer, Dean,Wendy, Ferguson-Smith,Anne, Fundele,Reinald, ...
Imprinted genes in mammals are expressed from only one of the parental chromosomes, and are crucial for placental development and fetal growth. The insulin-like growth factor II gene (Igf2) is...
Zechner,Ulrich, Hemberger,Myriam, Constância,Miguel, Orth,Annie, Dragatsis,Ioannis, Lüttges,Angela, ...
It has been shown previously that abnormal placental growth occurs in crosses and backcrosses between different mouse (Mus) species. In such crosses, late gestation placentas may weigh between 13 and...
Placental-specific IGF-II is a major modulator of placental and fetal growth (2002)
Constância, Miguel, Hemberger, Myriam, Hughes, Jennifer, Dean, Wendy, Ferguson-Smith, Anne, Fundele, Reinald, ...
Imprinted genes in mammals are expressed from only one of the parental chromosomes, and are crucial for placental development and fetal growth. The insulin-like growth factor II gene (Igf2) is...
Zechner, Ulrich, Hemberger, Myriam, Constância, Miguel, Orth, Annie, Dragatsis, Ioannis, Lüttges, Angela, ...
It has been shown previously that abnormal placental growth occurs in crosses and backcrosses between different mouse (Mus) species. In such crosses, late gestation placentas may weigh between 13 and...
An intragenic methylated region in the imprinted Igf2 gene augments transcription
Murrell, Adele, Heeson, Sarah, Bowden, Lucy, Constância, Miguel, Dean, Wendy, Kelsey, Gavin, ...
DNA methylation is usually associated with transcriptional silencing, but in the imprinted mouse Igf2 gene, the paternally expressed copy is methylated in two discrete differentially methylated...
Constância, Miguel, Angiolini, Emily, Sandovici, Ionel, Smith, Paul, Smith, Rachel, Kelsey, Gavin, ...
The mammalian fetus is unique in its dependence during gestation on the supply of maternal nutrients through the placenta. Maternal supply and fetal demand for nutrients need to be fine tuned for...
An intragenic methylated region in the imprinted Igf2 gene augments transcription
Murrell, Adele, Heeson, Sarah, Bowden, Lucy, Constância, Miguel, Dean, Wendy, Kelsey, Gavin, ...
DNA methylation is usually associated with transcriptional silencing, but in the imprinted mouse Igf2 gene, the paternally expressed copy is methylated in two discrete differentially methylated...
Constância, Miguel, Angiolini, Emily, Sandovici, Ionel, Smith, Paul, Smith, Rachel, Kelsey, Gavin, ...
The mammalian fetus is unique in its dependence during gestation on the supply of maternal nutrients through the placenta. Maternal supply and fetal demand for nutrients need to be fine tuned for...
Regulation of supply and demand for maternal nutrients in mammals by imprinted genes
Reik, Wolf, Constância, Miguel, Fowden, Abigail, Anderson, Neil, Dean, Wendy, Ferguson-Smith, Anne, ...
The placenta has evolved in eutherian mammals primarily to provide nutrients for the developing fetus. The genetic control of the regulation of supply and demand for maternal nutrients is not...