Mikael Bodelsson

Human antimicrobial peptide LL-37 is present in atherosclerotic plaques and induces death of vascular smooth muscle cells: a laboratory study (2006)

Ciornei, Cristina D, Tapper, Hans, Bjartell, Anders, Sternby, Nils H, Bodelsson, Mikael

Abstract Background Death of smooth muscle cells in the atherosclerotic plaques makes the plaques more prone to rupture, which can initiate an acute ischemic event. The development of atherosclerosis...

Hypersensitivity to noradrenaline in human omental vein but not artery isolated from a patient with idiopathic orthostatic hypotension. (2002)

Hidestål, Joakim, Fredriksen, Sven, Hallén, Magnus, Westerdahl, Johan, Thysell, Hans, Bodelsson, Mikael

We investigated the smooth muscle contraction in response to noradrenaline (NA), endothelin-1 (ET) and 5-hydroxytryptamine (5-HT) in the omental artery and vein segments from a 67-year-old woman with...

Bactericidal activity of human eosinophilic granulocytes against Escherichia coli (2001)

Persson, Terese, Andersson, Pia, Bodelsson, Mikael, Laurell, Martin, Malm, Johan, Egesten, Arne

Eosinophils participate in allergic inflammation and may have roles in the bodys defense against helminthic infestation. Even under noninflammatory conditions, eosinophils are present in the mucosa...

Binding of [3H]-5-hydroxytryptamine to human coronary artery and bypass graft vessels (1996)

Dahm, Peter L., Bodelsson, Mikael, Törnebrandt, Kenneth, Muddle, John R., Sykes, Rachel M., Yacoub, Magdi, ...

Objectives5-Hydroxytryptamine (5-HT) has a wide range of vascular effects mediated via specific receptors and it has been suggested to be a mediator in ischemic heart disease. The aim of the present...

Bactericidal Activity of Human Eosinophilic Granulocytes against Escherichia coli

Persson, Terese, Andersson, Pia, Bodelsson, Mikael, Laurell, Martin, Malm, Johan, Egesten, Arne

Eosinophils participate in allergic inflammation and may have roles in the body's defense against helminthic infestation. Even under noninflammatory conditions, eosinophils are present in the mucosa...

Antimicrobial and Chemoattractant Activity, Lipopolysaccharide Neutralization, Cytotoxicity, and Inhibition by Serum of Analogs of Human Cathelicidin LL-37

Ciornei, Cristina D., Sigurdardóttir, Thorgerdur, Schmidtchen, Artur, Bodelsson, Mikael

Antimicrobial peptides have been evaluated in vitro and in vivo as alternatives to conventional antibiotics. Apart from being antimicrobial, the native human cathelicidin-derived peptide LL-37 (amino...

Bactericidal Activity of Human Eosinophilic Granulocytes against Escherichia coli

Persson, Terese, Andersson, Pia, Bodelsson, Mikael, Laurell, Martin, Malm, Johan, Egesten, Arne

Eosinophils participate in allergic inflammation and may have roles in the body's defense against helminthic infestation. Even under noninflammatory conditions, eosinophils are present in the mucosa...

Antimicrobial and Chemoattractant Activity, Lipopolysaccharide Neutralization, Cytotoxicity, and Inhibition by Serum of Analogs of Human Cathelicidin LL-37

Ciornei, Cristina D., Sigurdardóttir, Thorgerdur, Schmidtchen, Artur, Bodelsson, Mikael

Antimicrobial peptides have been evaluated in vitro and in vivo as alternatives to conventional antibiotics. Apart from being antimicrobial, the native human cathelicidin-derived peptide LL-37 (amino...

In Silico Identification and Biological Evaluation of Antimicrobial Peptides Based on Human Cathelicidin LL-37

Sigurdardottir, Thorgerdur, Andersson, Pia, Davoudi, Mina, Malmsten, Martin, Schmidtchen, Artur, Bodelsson, Mikael

Bacterial lipopolysaccharides (LPS) are important triggers of the widespread inflammatory response, which contributes to the development of multiple organ failure during sepsis. The helical...

Endothelium-dependent relaxation by substance P in human isolated omental arteries and veins: relative contribution of prostanoids, nitric oxide and hyperpolarization

Wallerstedt, Susanna M, Bodelsson, Mikael

The objective of the present study was to investigate human omental arteries and veins with respect to: (i) the contractile effect of the thromboxane A2 analogue U46619, (ii) endothelium-dependency...

Differential effect of propofol on sympathetic neurotransmission in isolated human omental arteries and veins

Wallerstedt, Susanna M, Bodelsson, Mikael

The present study was undertaken to elucidate the effect of propofol on sympathetic neurotransmission in isolated human omental vessels.Segments of both arteries and veins were exposed to 0, 10−7,...