Minou Adib-Conquy

Translocation of bacterial NOD2 agonist and its link with inflammation (2009)

Kim, Oh, Monsel, Antoine, Bertrand, Michèle, Cavaillon, Jean-Marc, Coriat, Pierre, Adib-Conquy, Minou

Abstract Introduction The gut is often considered as the motor of critical illness through bacterial translocation, which amplifies the inflammatory response and alters the immune status. However,...

Bench-to-bedside review: Endotoxin tolerance as a model of leukocyte reprogramming in sepsis (2006)

Cavaillon, Jean-Marc, Adib-Conquy, Minou

Abstract Endotoxin tolerance is defined as a reduced responsiveness to a lipopolysaccharide (LPS) challenge following a first encounter with endotoxin. Endotoxin tolerance protects against a lethal...

Bacterial secretion of the Fab fragment of a mouse monoclonal IgM that reacts with IgG variable regions (1995)

Adib-Conquy, Minou, Gilbert, Michèle, Christodoulou, Christina, Avrameas, Stratis

In this report, we describe the expression system that enabled us to produce in Escherichia coli the Fab fragment of a mouse IgM that has previously been shown to inhibit the binding of IgG to...

Bench-to-bedside review: Endotoxin tolerance as a model of leukocyte reprogramming in sepsis

Cavaillon, Jean-Marc, Adib-Conquy, Minou

Endotoxin tolerance is defined as a reduced responsiveness to a lipopolysaccharide (LPS) challenge following a first encounter with endotoxin. Endotoxin tolerance protects against a lethal challenge...

Contribution of Phagocytosis and Intracellular Sensing for Cytokine Production by Staphylococcus aureus-Activated Macrophages▿

Kapetanovic, Ronan, Nahori, Marie-Anne, Balloy, Viviane, Fitting, Catherine, Philpott, Dana J., Cavaillon, Jean-Marc, ...

Toll-like receptors (TLRs) are involved in the sensing of microbially derived compounds. We analyzed the contribution of these receptors to cytokine production by macrophages following stimulation...

Simple Method for Repurification of Endotoxins for Biological Use▿

Tirsoaga, Alina, Novikov, Alexey, Adib-Conquy, Minou, Werts, Catherine, Fitting, Catherine, Cavaillon, Jean-Marc, ...

A method for obtaining highly purified endotoxin (lipopolysaccharide [LPS]) in a few hours by repurification of commercial or laboratory preparations was devised. It avoids the use of phenol, which...

Neutrophils in Cystic Fibrosis Display a Distinct Gene Expression Pattern

Adib-Conquy, Minou, Pedron, Thierry, Petit-Bertron, Anne-France, Tabary, Olivier, Corvol, Harriet, Jacquot, Jacky, ...

We compared gene expression in blood neutrophils (polymorphonuclear leukocytes, or PMNs) collected from healthy subjects with those of cystic fibrosis (CF) patients devoid of bacterial colonization....