Miriam Postan

Evaluación inmunológica del tratamiento con benznidazol en la enfermedad de Chagas crónica (2008)

Graciela L. Bertocchi, María G. Álvarez, Damián Pérez, Alejandro Armenti, Rodolfo J. Viotti, Bruno Lococo, ...

Para determinar el efecto del tratamiento con benznidazol sobre las células T de memoria específica para Trypanosoma cruzi, se seleccionaron 47 pacientes con tres reacciones serológicas positivas...

CD8+ T-Cell Responses to Trypanosoma cruzi Are Highly Focused on Strain-Variant trans-Sialidase Epitopes (2006)

Diana L. Martin, D. Brent Weatherly, Susana A. Laucella, Melissa A. Cabinian, Matthew T. Crim, Susan Sullivan, ...

CD8+ T cells are crucial for control of a number of medically important protozoan parasites, including Trypanosoma cruzi, the agent of human Chagas disease. Yet, in contrast to the wealth of...

Trypanosoma cruzi modulates the profile of memory CD8+ T cells in chronic Chagas' disease patients (2006)

Albareda, María Cecilia, Laucella, Susana Adriana, Alvarez, María Gabriela, Armenti, Alejandro Hector, Bertochi, Graciela, Tarleton, Rick L., ...

We present a cross-sectional analysis of the maturation and migratory properties of the memory CD8+ T cell compartment, in relation to the severity of heart disease in individuals with chronic...

CARDIAC MYOCYTE HYPERTROPHY AND PROLIFERATING CELL NUCLEAR ANTIGEN EXPRESSION IN WISTAR RATS INFECTED WITH TRYPANOSOMA CRUZI (2002)

María Rosa Arnaiz, Laura Edith Fichera, Miriam Postan

Chagasic cardiomyopathy is a major life-threatening complication of Trypanosoma cruzi infection in human beings. This study focuses on the hypertrophic and hyperplastic mechanisms underlying the...

Intracellular Growth of Trypanosoma cruzi in Cardiac Myocytes Is Inhibited by Cytokine-Induced Nitric Oxide Release

Fichera, Laura Edith, Albareda, Maria Cecilia, Laucella, Susana Adriana, Postan, Miriam

The effect of interleukin-1β (IL-1β), tumor necrosis factor alpha (TNF-α), and gamma interferon (IFN-γ) on Trypanosoma cruzi multiplication and nitric oxide (NO) production in cardiac myocytes...

CD8+ T-Cell Responses to Trypanosoma cruzi Are Highly Focused on Strain-Variant trans-Sialidase Epitopes

Martin, Diana L, Weatherly, D. Brent, Laucella, Susana A, Cabinian, Melissa A, Crim, Matthew T, Sullivan, Susan, ...

CD8+ T cells are crucial for control of a number of medically important protozoan parasites, including Trypanosoma cruzi, the agent of human Chagas disease. Yet, in contrast to the wealth of...

Intracellular Growth of Trypanosoma cruzi in Cardiac Myocytes Is Inhibited by Cytokine-Induced Nitric Oxide Release

Fichera, Laura Edith, Albareda, Maria Cecilia, Laucella, Susana Adriana, Postan, Miriam

The effect of interleukin-1β (IL-1β), tumor necrosis factor alpha (TNF-α), and gamma interferon (IFN-γ) on Trypanosoma cruzi multiplication and nitric oxide (NO) production in cardiac myocytes...

CD8+ T-Cell Responses to Trypanosoma cruzi Are Highly Focused on Strain-Variant trans-Sialidase Epitopes

Martin, Diana L, Weatherly, D. Brent, Laucella, Susana A, Cabinian, Melissa A, Crim, Matthew T, Sullivan, Susan, ...

CD8+ T cells are crucial for control of a number of medically important protozoan parasites, including Trypanosoma cruzi, the agent of human Chagas disease. Yet, in contrast to the wealth of...

HLA Class I-T Cell Epitopes from trans-Sialidase Proteins Reveal Functionally Distinct Subsets of CD8+ T Cells in Chronic Chagas Disease

Alvarez, María G., Postan, Miriam, Weatherly, D. Brent, Albareda, María C., Sidney, John, Sette, Alessandro, ...

At present, 16–20 million people in Central and South America are infected with Trypanosoma cruzi, the causative agent of Chagas disease in humans. The primary clinical consequence of the infection...

High Throughput Selection of Effective Serodiagnostics for Trypanosoma cruzi infection

Cooley, Gretchen, Etheridge, R. Drew, Boehlke, Courtney, Bundy, Becky, Weatherly, D. Brent, Minning, Todd, ...

The diagnosis of Trypanosoma cruzi infection (the cause of human Chagas disease) is difficult because the symptoms of the infection are often absent or non-specific, and because the parasites...