Association of polymorphisms in the MTH1 gene with small cell lung carcinoma risk (2006)
Kohno, Takashi, Sakiyama, Tokuki, Kunitoh, Hideo, Goto, Koichi, Nishiwaki, Yutaka, Saito, Daizo, ...
Fifty single-nucleotide polymorphisms (SNPs) associated with amino acid changes in 36 genes involved in diverse DNA repair pathways were assessed for associations with risk for small cell lung...
Association of polymorphisms in the MTH1 gene with small cell lung carcinoma risk (2006)
Kohno, Takashi, Sakiyama, Tokuki, Kunitoh, Hideo, Goto, Koichi, Nishiwaki, Yutaka, Saito, Daizo, ...
Fifty single-nucleotide polymorphisms (SNPs) associated with amino acid changes in 36 genes involved in diverse DNA repair pathways were assessed for associations with risk for small cell lung...
Nomenclature for Runt-related (RUNX) proteins (2004)
Van Wijnen, Andre J., Stein, Gary S., Gergen, J. Peter, Groner, Yoram, Hiebert, Scott W., Ito, Yoshiaki, ...
Fujiwara, Kyoko, Ochiai, Masako, Ohta, Tsutomu, Ohki, Misao, Aburatani, Hiroyuki, Nagao, Minako, ...
Colon cancers develop after accumulation of multiple genetic and epigenetic alterations in colon epithelial cells. To shed light on global changes in gene expression of colon cancers, and to gain...
Fujiwara, Kyoko, Ochiai, Masako, Ohta, Tsutomu, Ohki, Misao, Aburatani, Hiroyuki, Nagao, Minako, ...
Colon cancers develop after accumulation of multiple genetic and epigenetic alterations in colon epithelial cells. To shed light on global changes in gene expression of colon cancers and to gain...
Abe, Masanobu, Yamashita, Satoshi, Kuramoto, Takashi, Hirayama, Yoshikazu, Tsukamoto, Tetsuya, Ohta, Tsutomu, ...
Rat stomach carcinomas induced by N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) are widely used as a model for differentiated-type human stomach carcinomas. Here, we analyzed expression profiles in...
Abe, Masanobu, Yamashita, Satoshi, Kuramoto, Takashi, Hirayama, Yoshikazu, Tsukamoto, Tetsuya, Ohta, Tsutomu, ...
Rat stomach carcinomas induced by N-methyl-N′-nitro-N-nitrosoguanidine (MNNG) are widely used as a model for differentiated-type human stomach carcinomas. Here, we analyzed expression profiles in...
Abe, Masanobu, Yamashita, Satoshi, Kuramoto, Takashi, Hirayama, Yoshikazu, Tsukamoto, Tetsuya, Ohta, Tsutomu, ...
Rat stomach carcinomas induced by N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) are widely used as a model for differentiated-type human stomach carcinomas. Here, we analyzed expression profiles in...
Kitamura, Eiko, Hosoda, Fumie, Fukushima, Michiyo, Asakawa, Shuichi, Shimizu, Nobuyoshi, Imai, Takashi, ...
Despite the presence of several human disease genes on chromosome 11q13, few of them have been molecularly cloned. Here, we report the construction of a contig map encompassing 11q13.1–q13.3 using...
Ohira, Miki, Ootsuyama, Akira, Suzuki, Emiko, Ichikawa, Hitoshi, Seki, Naohiko, Nagase, Takahiro, ...
The Down syndrome (DS) region on chromosome 21, which is responsible for the DS main features, has been defined by analysis of DS patients with partial trisomy 21. Within the DS region, we...
Sixty New STSs (Sequence-Tagged Sites) of Human Chromosome 21 (1994)
Tanahashi, Hiroshi, Ito, Takashi, Hattori, Masahira, Ohira, Miyuki, Ohki, Misao, Tashiro, Kosuke, ...
From human chromosome 21-specific libraries, 22 SfiI linking clones and 38 P1 clones were isolated and regionally mapped on the chromosome. The terminal sequences of these clones were determined and...
An F factor based cloning system for large DNA fragments (1990)
Hosoda, Fumie, Nishimura, Susumu, Uchida, Hisao, Ohki, Misao
An effective technique using an Escherichia coli plasmid system was developed to clone fragments of exogenous DNA of as large as 100 kilobase pairs. The characteristic features of this technique are...
Tracking bacterial DNA replication forks in vivo by pulsed field gel electrophoresis (1989)
Ohki, Misao, Smith, Cassandra L.
The location of chromosomal DNA replication forks was identified in synchronously replicating E. coli cultures by pulse labeling DNA at specific times with 14C-thymidine and following incorporation...
Nucleotide Sequence of the Regulatory Region of malB Operons in E. coli (1983)
OHSUMI, Mariko, SEKIYA, Takao, NISHIMURA, Susumu, OHKI, Misao
The nucleotide sequence of a cloned section of the Escherichia coli chromosome containing the promoter regions of the malB divergent operons was determined. The region of the proximal gene, malE of...
The nucleotide sequence of Bacillus Subtuis tRNA genes (1983)
Yamada, Yuko, Ohki, Misao, Ishikura, Hisayuki
Clones earring Bacillue aubtilis tRNA genes were isolated from a 003B3;816 library. A recombinant phage 003B3;816-BS83 which was hybridized effectively with unfractionated tRNA probes contained a...
Murakami, Yoshinori, Nobukuni, Takahiro, Tamura, Kenji, Maruyama, Tomoko, Sekiya, Takao, Arai, Yasuhito, ...
Loss of heterozygosity on chromosome 11q23 is observed at high frequency in human nonsmall cell lung carcinomas (NSCLCs), suggesting the presence of a tumor suppressor gene. Previous analysis of DNA...
Ichikawa, Hitoshi, Shimizu, Kimiko, Katsu, Rieko, Ohki, Misao
The FUS (TLS)-ERG chimeric protein associated with t(16;21)(p11;q22) acute myeloid leukemia is structurally similar to the Ewing’s sarcoma chimeric transcription factor EWS-ERG. We found that both...
Kitabayashi, Issay, Ida, Kohmei, Morohoshi, Fumiko, Yokoyama, Akihiko, Mitsuhashi, Naoko, Shimizu, Kimiko, ...
The AML1-CBFβ transcription factor complex is essential for the definitive hematopoiesis of all lineages and is the most frequent target of chromosomal rearrangements in human leukemia. In the...
Yokoyama, Akihiko, Tanaka, Michiko, Matsuda, Go, Kato, Kentaro, Kanamori, Mikiko, Kawasaki, Hiroshi, ...
Epstein-Barr virus (EBV) nuclear antigen leader protein (EBNA-LP) is a phosphoprotein suggested to play important roles in EBV-induced immortalization of B cells. One of the potential functions of...
Activation of AML1-mediated transcription by MOZ and inhibition by the MOZ–CBP fusion protein
Kitabayashi, Issay, Aikawa, Yukiko, Nguyen, Lan Anh, Yokoyama, Akihiko, Ohki, Misao
The AML1–CBFβ transcription factor complex is the most frequent target of specific chromosome translocations in human leukemia. The MOZ gene, which encodes a histone acetyltransferase (HAT), is...
Tachibana, Makoto, Sugimoto, Kenji, Nozaki, Masami, Ueda, Jun, Ohta, Tsutomu, Ohki, Misao, ...
Covalent modification of histone tails is crucial for transcriptional regulation, mitotic chromosomal condensation, and heterochromatin formation. Histone H3 lysine 9 (H3-K9) methylation catalyzed by...
Mutant of Escherichia coli K-12 Deficient for Detergent-Resistant Phospholipase A
Ohki, Misao, Doi, Osamu, Nojima, Shoshichi
A mutant deficient for detergent-resistant (DR) phospholipase A was isolated from Escherichia coli K-12. Because the enzyme is membrane-bound and the substrate is a lipid, a special procedure was...
Murakami, Yoshinori, Nobukuni, Takahiro, Tamura, Kenji, Maruyama, Tomoko, Sekiya, Takao, Arai, Yasuhito, ...
Loss of heterozygosity on chromosome 11q23 is observed at high frequency in human nonsmall cell lung carcinomas (NSCLCs), suggesting the presence of a tumor suppressor gene. Previous analysis of DNA...
Ichikawa, Hitoshi, Shimizu, Kimiko, Katsu, Rieko, Ohki, Misao
The FUS (TLS)-ERG chimeric protein associated with t(16;21)(p11;q22) acute myeloid leukemia is structurally similar to the Ewing’s sarcoma chimeric transcription factor EWS-ERG. We found that both...
Kitabayashi, Issay, Ida, Kohmei, Morohoshi, Fumiko, Yokoyama, Akihiko, Mitsuhashi, Naoko, Shimizu, Kimiko, ...
The AML1-CBFβ transcription factor complex is essential for the definitive hematopoiesis of all lineages and is the most frequent target of chromosomal rearrangements in human leukemia. In the...
Yokoyama, Akihiko, Tanaka, Michiko, Matsuda, Go, Kato, Kentaro, Kanamori, Mikiko, Kawasaki, Hiroshi, ...
Epstein-Barr virus (EBV) nuclear antigen leader protein (EBNA-LP) is a phosphoprotein suggested to play important roles in EBV-induced immortalization of B cells. One of the potential functions of...
Activation of AML1-mediated transcription by MOZ and inhibition by the MOZ–CBP fusion protein
Kitabayashi, Issay, Aikawa, Yukiko, Nguyen, Lan Anh, Yokoyama, Akihiko, Ohki, Misao
The AML1–CBFβ transcription factor complex is the most frequent target of specific chromosome translocations in human leukemia. The MOZ gene, which encodes a histone acetyltransferase (HAT), is...
Tachibana, Makoto, Sugimoto, Kenji, Nozaki, Masami, Ueda, Jun, Ohta, Tsutomu, Ohki, Misao, ...
Covalent modification of histone tails is crucial for transcriptional regulation, mitotic chromosomal condensation, and heterochromatin formation. Histone H3 lysine 9 (H3-K9) methylation catalyzed by...
Mutant of Escherichia coli K-12 Deficient for Detergent-Resistant Phospholipase A
Ohki, Misao, Doi, Osamu, Nojima, Shoshichi
A mutant deficient for detergent-resistant (DR) phospholipase A was isolated from Escherichia coli K-12. Because the enzyme is membrane-bound and the substrate is a lipid, a special procedure was...
Ishida, Michiko, Miyamoto, Mamiko, Naitoh, Sayu, Tatsuda, Daisuke, Hasegawa, Tadashi, Nemoto, Takeshi, ...
Chromosomal translocations are frequently associated with soft-tissue sarcomas. Fusion proteins generated by such translocations often play critical roles in tumorigenesis. Therefore, it is important...
Tsuchiya, Akira, Sakamoto, Michiie, Yasuda, Jun, Chuma, Makoto, Ohta, Tsutomu, Ohki, Misao, ...
Of all of the epithelial ovarian cancers, clear cell carcinoma (CCC) of the ovary has the worst prognosis. We applied the oligonucleotide array technique to identify genes generally involved in CCC....
Marshall, Leslie J., Moore, Amy C., Ohki, Misao, Kitabayashi, Issay, Patterson, David, Ornelles, David A.
The localization of the adenovirus E1B-55K-E4orf6 protein complex is critical for its function. Prior studies demonstrated that E4orf6 directs the nuclear localization of E1B-55K in human cells and...