Silveira, Henrique, Ramos, Susana, Abrantes, Patrícia, Lopes, Luís, Do Rosario, Virgílio E, Abrahamsen, Mitchell S
Abstract Background The anti-malarial chloroquine can modulate the outcome of infection during the Plasmodium sporogonic development, interfering with Plasmodium gene expression and subsequently,...
Mullapudi, Nandita, Lancto, Cheryl A, Abrahamsen, Mitchell S, Kissinger, Jessica C
Abstract Background Cryptosporidium parvum is a unicellular eukaryote in the phylum Apicomplexa. It is an obligate intracellular parasite that causes diarrhea and is a significant AIDS-related...
Cryptosporidium Parvum Genome Project (2006)
A lack of basic understanding of parasite biology has been a limiting factor in designing effective means of treating and preventing disease caused by Cryptosporidium parvum. Since the genomic DNA...
Huang, Jinling, Mullapudi, Nandita, Lancto, Cheryl A, Scott, Marla, Abrahamsen, Mitchell S, Kissinger, Jessica C
Abstract Background The apicomplexan parasite Cryptosporidium parvum is an emerging pathogen capable of causing illness in humans and other animals and death in immunocompromised individuals. No...
Madern, Dominique, Cai, Xiaomin, Abrahamsen, Mitchell S., Zhu, Guan
We have expressed the L-lactate dehydrogenase (LDH) and L-malate dehydrogenase (malDH) genes from the apicomplexan Cryptosporidium parvum (CpLDH1 and CpMalDH1) as maltose-binding protein (MBP) fusion...
CryptoDB: the Cryptosporidium genome resource (2004)
Puiu, Daniela, Enomoto, Shinichiro, Buck, Gregory A., Abrahamsen, Mitchell S., Kissinger, Jessica C.
CryptoDB (http://CryptoDB.org) represents a collaborative effort to locate all genome data for the apicomplexan parasite Cryptosporidium parvum in a single user‐friendly database. CryptoDB...
Madern, Dominique, Cai, Xiaomin, Abrahamsen, Mitchell S., Zhu, Guan
We have expressed the L-lactate dehydrogenase (LDH) and L-malate dehydrogenase genes from the apicomplexan Cryptosporidium parvum (CpLDH1 and CpMalDH1) as maltose-binding protein (MBP) fusion...
Madern, Dominique, Cai, Xiaomin, Abrahamsen, Mitchell S., Zhu, Guan
We have expressed the L-lactate dehydrogenase (LDH) and L-malate dehydrogenase genes from the apicomplexan Cryptosporidium parvum (CpLDH1 and CpMalDH1) as maltose-binding protein (MBP) fusion...
Cryptosporidium parvum Genome Project (2001)
A lack of basic understanding of parasite biology has been a limiting factor in designing effective means of treating and preventing disease caused by Cryptosporidium parvum. Since the genomic DNA...
A Random Survey of the Cryptosporidium parvum Genome
Liu, Chang, Vigdorovich, Vladimir, Kapur, Vivek, Abrahamsen, Mitchell S.
Cryptosporidium parvum is an obligate intracellular pathogen responsible for widespread infections in humans and animals. The inability to obtain purified samples of this organism’s various...
Weiss, Douglas J., Evanson, Oral A., McClenahan, David J., Abrahamsen, Mitchell S., Walcheck, Bruce K.
Mycobacterium avium subsp. paratuberculosis and Mycobacterium avium subsp. avium are antigenically and genetically very similar organisms; however, they differ markedly in their virulence for cattle....
Lafleur, Rhonda L., Abrahamsen, Mitchell S., Maheswaran, Samuel K.
Pasteurella haemolytica serotype 1 is the bacterial agent responsible for the pathophysiological events associated with bovine pneumonic pasteurellosis. Our previous studies support a role for the...
Genetic complementation in apicomplexan parasites
Striepen, Boris, White, Michael W., Li, Catherine, Guerini, Michael N., Malik, S.-Banoo, Logsdon, John M., ...
A robust forward genetic model for Apicomplexa could greatly enhance functional analysis of genes in these important protozoan pathogens. We have developed and successfully tested a genetic...
Weiss, Douglas J., Evanson, Oral A., Moritz, Andreas, Deng, Ming Qi, Abrahamsen, Mitchell S.
Mycobacterium avium subsp. paratuberculosis and Mycobacterium avium subsp. avium are antigenically and genetically similar organisms; however, they differ in their virulence for cattle. M. avium...
Cryptosporidium parvum Genes Containing Thrombospondin Type 1 Domains
Deng, Mingqi, Templeton, Thomas J., London, Nicole R., Bauer, Carrey, Schroeder, Alison A., Abrahamsen, Mitchell S.
Cryptosporidium parvum is recognized as an enteropathogen of great worldwide medical and veterinary importance, yet understanding of its pathogenesis has been hampered in part by limited knowledge of...
CryptoDB: the Cryptosporidium genome resource
Puiu, Daniela, Enomoto, Shinichiro, Buck, Gregory A., Abrahamsen, Mitchell S., Kissinger, Jessica C.
CryptoDB (http://CryptoDB.org) represents a collaborative effort to locate all genome data for the apicomplexan parasite Cryptosporidium parvum in a single user-friendly database. CryptoDB currently...
Templeton, Thomas J., Lancto, Cheryl A., Vigdorovich, Vladimir, Liu, Chang, London, Nicole R., Hadsall, Kelly Z., ...
Coccidian parasites are transmitted via a fecal oocyst stage that is exceptionally resistant to environmental stress and harsh chemical treatments, which allows parasites to stably persist outside a...
Comparative Analysis of Apicomplexa and Genomic Diversity in Eukaryotes
Templeton, Thomas J., Iyer, Lakshminarayan M., Anantharaman, Vivek, Enomoto, Shinichiro, Abrahante, Juan E., Subramanian, G.M., ...
The apicomplexans Plasmodium and Cryptosporidium have developed distinctive adaptations via lineage-specific gene loss and gene innovation in the process of diverging from a common parasitic...
Huang, Jinling, Mullapudi, Nandita, Lancto, Cheryl A, Scott, Marla, Abrahamsen, Mitchell S, Kissinger, Jessica C
An analysis of Cryptosporidium parvum genes of likely endosymbiont or prokaryotic origin supports the hypothesis that C. arvum evolved from a plastid-containing lineage.
A Random Survey of the Cryptosporidium parvum Genome
Liu, Chang, Vigdorovich, Vladimir, Kapur, Vivek, Abrahamsen, Mitchell S.
Cryptosporidium parvum is an obligate intracellular pathogen responsible for widespread infections in humans and animals. The inability to obtain purified samples of this organism’s various...
Weiss, Douglas J., Evanson, Oral A., McClenahan, David J., Abrahamsen, Mitchell S., Walcheck, Bruce K.
Mycobacterium avium subsp. paratuberculosis and Mycobacterium avium subsp. avium are antigenically and genetically very similar organisms; however, they differ markedly in their virulence for cattle....
Lafleur, Rhonda L., Abrahamsen, Mitchell S., Maheswaran, Samuel K.
Pasteurella haemolytica serotype 1 is the bacterial agent responsible for the pathophysiological events associated with bovine pneumonic pasteurellosis. Our previous studies support a role for the...
Genetic complementation in apicomplexan parasites
Striepen, Boris, White, Michael W., Li, Catherine, Guerini, Michael N., Malik, S.-Banoo, Logsdon, John M., ...
A robust forward genetic model for Apicomplexa could greatly enhance functional analysis of genes in these important protozoan pathogens. We have developed and successfully tested a genetic...
Weiss, Douglas J., Evanson, Oral A., Moritz, Andreas, Deng, Ming Qi, Abrahamsen, Mitchell S.
Mycobacterium avium subsp. paratuberculosis and Mycobacterium avium subsp. avium are antigenically and genetically similar organisms; however, they differ in their virulence for cattle. M. avium...
Cryptosporidium parvum Genes Containing Thrombospondin Type 1 Domains
Deng, Mingqi, Templeton, Thomas J., London, Nicole R., Bauer, Carrey, Schroeder, Alison A., Abrahamsen, Mitchell S.
Cryptosporidium parvum is recognized as an enteropathogen of great worldwide medical and veterinary importance, yet understanding of its pathogenesis has been hampered in part by limited knowledge of...
CryptoDB: the Cryptosporidium genome resource
Puiu, Daniela, Enomoto, Shinichiro, Buck, Gregory A., Abrahamsen, Mitchell S., Kissinger, Jessica C.
CryptoDB (http://CryptoDB.org) represents a collaborative effort to locate all genome data for the apicomplexan parasite Cryptosporidium parvum in a single user-friendly database. CryptoDB currently...
Templeton, Thomas J., Lancto, Cheryl A., Vigdorovich, Vladimir, Liu, Chang, London, Nicole R., Hadsall, Kelly Z., ...
Coccidian parasites are transmitted via a fecal oocyst stage that is exceptionally resistant to environmental stress and harsh chemical treatments, which allows parasites to stably persist outside a...
Comparative Analysis of Apicomplexa and Genomic Diversity in Eukaryotes
Templeton, Thomas J., Iyer, Lakshminarayan M., Anantharaman, Vivek, Enomoto, Shinichiro, Abrahante, Juan E., Subramanian, G.M., ...
The apicomplexans Plasmodium and Cryptosporidium have developed distinctive adaptations via lineage-specific gene loss and gene innovation in the process of diverging from a common parasitic...
Huang, Jinling, Mullapudi, Nandita, Lancto, Cheryl A, Scott, Marla, Abrahamsen, Mitchell S, Kissinger, Jessica C
An analysis of Cryptosporidium parvum genes of likely endosymbiont or prokaryotic origin supports the hypothesis that C. arvum evolved from a plastid-containing lineage.
Silveira, Henrique, Ramos, Susana, Abrantes, Patrícia, Lopes, Luís Filipe, Do Rosario, Virgílio E, Abrahamsen, Mitchell S
Pradel, Gabriele, Hayton, Karen, Aravind, L., Iyer, Lakshminarayan M., Abrahamsen, Mitchell S., Bonawitz, Annemarie, ...
The recent sequencing of several apicomplexan genomes has provided the opportunity to characterize novel antigens essential for the parasite life cycle that might lead to the development of new...
Cryptosporidium Parvum Genome Project
A lack of basic understanding of parasite biology has been a limiting factor in designing effective means of treating and preventing disease caused by Cryptosporidium parvum. Since the genomic DNA...
Liu, Jin, Enomoto, Shinichiro, Lancto, Cheryl A., Abrahamsen, Mitchell S., Rutherford, Mark S.
Cryptosporidium parvum is an obligate intracellular protozoan capable of causing severe diarrheal disease in a wide variety of mammals, including humans. C. parvum infection has been associated with...
Liu, Jin, Deng, Mingqi, Lancto, Cheryl A., Abrahamsen, Mitchell S., Rutherford, Mark S., Enomoto, Shinichiro
The impact of Cryptosporidium parvum infection on host cell gene expression was investigated by microarray analysis with an in vitro model using human ileocecal HCT-8 adenocarcinoma cells. We found...