Mitsuru Sato

The Preliminary Evaluation of MBP-light with Two Protocol Policies for A Massively Parallel Processor -- JUMP-1 -- (2007)

Inoue Hiroaki, Ken-ichiro Anjo, Junji Yamamoto, Jun Tanabe, Masaki Wakabayashi, Mitsuru Sato, ...

A massively parallel processor called JUMP-1 has been developed to build an efficient cache coherent-distributed shared memory (DSM) on a large system with more than 1000 processors. Here, the...

Impaired LPS-induced signaling in microglia overexpressing the Wiskott Aldrich syndrome protein N-terminal domain (2007)

Sato, Mitsuru, Ogihara, Kazumasa, Sawahata, Ryoko, Sekikawa, Kenji, Kitani, Hiroshi

Wiskott–Aldrich syndrome protein (WASP) plays important roles in TCR signaling, but its roles in signal transduction in innate immune cells have not been well characterized. As microglia are the...

Intercellular Adhesive Structures Between Stellate Cells – An Analysis in Cultured Human Hepatic Stellate Cells (2004)

Imai, Katsuyuki, Sato, Mitsuru, Sato, Takeya, Kojima, Naosuke, Miura, Mitsutaka, Higashi, Nobuyo, ...

Abstract To investigate whether or not hepatic stellate cells can form intercellular junctions with each other, we cultured human stellate cells (LI90) on different kinds of substrata. Intercellular...

Intralobular Distribution of Vitamin A-Storing Lipid Droplets in Hepatic Stellate Cells with Special Reference to Polar Bear and Arctic Fox (2004)

Higashi, Nobuyo, Imai, Katsuyuki, Sato, Mitsuru, Sato, Takeya, Kojima, Naosuke, Miura, Mitsutaka, ...

Abstract We examined the liver of adult polar bears, arctic foxes, and rats by gold chloride staining, fluorescence microscopy for the detection of autofluorescence of vitamin A, hematoxylin-eosin...

Regulation of matrix metallo-proteinase expression by extracellular matrix components in cultured hepatic stellate cells (2004)

Wang, Da-Ren, Sato, Mitsuru, Sato, Takeya, Kojima, Naosuke, Higashi, Nobuyo, Senoo, Haruki

Abstract Hepatic stellate cells (HSC) changed their morphology and function including production of matrix metalloproteinases (MMPs) in response to extracellular matrix (ECM) component used as a...

3-D structure of extracellular matrix regulates gene expression in cultured hepatic stellate cells to induce process elongation (2004)

Sato, Mitsuru, Sato, Takeya, Kojima, Naosuke, Imai, Katsuyuki, Higashi, Nobuyo, Wang, Da-Ren, ...

Abstract HSCs showed myofibroblast-like shapes when cultured on polystyrene surface or on type I collagen-coated surface, whereas HSCs cultured on type I collagen gel were induced to elongate...

Speeding up kernel scheduler by reducing cache misses - effects of cache coloring for a task structure (2002)

Freenix Track, Shuji Yamamura, Akira Hirai, Mitsuru Sato, Masao Yamamoto, Akira Naruse, ...

Rights to individual papers remain with the author or the author's employer. Permission is granted for noncommercial reproduction of the work for educational or research purposes. This copyright...

Isolation and characterization of a novel HS1 SH3 domain binding protein, HS1BP3 (1999)

Takemoto, Yoshihiro, Furuta, Masaaki, Sato, Mitsuru, Kubo, Masato, Hashimoto, Yasuhiro

We have isolated a novel gene, HS1BP3, which encodes an HS1 binding protein. Analysis of HS1BP3 cDNA indicates several potentially important segments, including a PX domain, a leucine zipper,...

Distinct binding patterns of HS1 to the Src SH2 and SH3 domains reflect possible mechanisms of recruitment and activation of downstream molecules (1996)

Takemoto, Yoshihiro, Sato, Mitsuru, Furuta, Masaaki, Hashimoto, Yasuhiro

We previously identified a gene, LckBP1, which encodes a protein that binds to the Lck SH3 domain and is identical to murine HS1. Using unstimulated T lymphocytes, we further demonstrated that Lck...

Reduction of Acid Sphingomyelinase Activity in Human Fibroblasts Induced by AY-9944 and Other Cationic Amphiphific Drugs (1985)

YOSHIDA, Yutaka, ARIMOTO, Kiyoshi, SATO, Mitsuru, SAKURAGAWA, Norio, ARIMA, Masataka, SATOYOSHI, Eijiro

AY-9944 (trans-1,4-bis(2-chlorobenzylaminoethyl)cyclohexane dihydrochloride), a cationic amphiphilic drug, caused a rapid, irreversible and dose-dependent reduction of acid sphingomyelinase activity...

Biochemical Studies on Liver Functions in Primary Cultured Hepatocytes of Adult Rats: I. Hormonal Effects on Cell Viability and Protein Synthesis (1978)

TANAKA, Keiji, SATO, Mitsuru, TOMITA, Yumiko, ICHIHARA, Akira

Liver parenchymal cells were isolated from adult rats by digesting liver slices or perfusing liver with collagenase. The cell yields were 1.5×l07 and 1.0×108 cells/g liver from slices and...

Proposed Methods for Estimation of Number and Size of Cells and Cytoplasmic Granules (1973)

SATO, Mitsuru, YONEMARU, Masayuki

A modified theoretical method for morphometry of spherical cytoplasmic granules was presented. The method, however, seemed to be unsufficiently for multiform structures such as the fat cells....

On the Secretory Granules of the Serous Cell in the Human Submandibular Gland (1966)

SATO, Mitsuru, NOGUCHI, Tsutomu, YOKOYAMA, Minoru, YOTSUMOTO, Mitsugu

Three specimens of the human submandibular gland were examined with the electron microscope in order to clarify the fine structure of secretory granules in the serous cell. Oval corpuscles were...

Uptake of denatured collagen into hepatic stellate cells: evidence for the involvement of urokinase plasminogen activator receptor-associated protein/Endo180

Mousavi, Seyed Ali, Sato, Mitsuru, Sporstøl, Marita, Smedsrød, Baard, Berg, Trond, Kojima, Naosuke, ...

Tissue remodelling is dependent on the integration of signals that control turnover of ECM (extracellular matrix). Breakdown and endocytosis of collagen, a major component of the ECM, is central to...

Uptake of denatured collagen into hepatic stellate cells: evidence for the involvement of urokinase plasminogen activator receptor-associated protein/Endo180

Mousavi, Seyed Ali, Sato, Mitsuru, Sporstøl, Marita, Smedsrød, Baard, Berg, Trond, Kojima, Naosuke, ...

Tissue remodelling is dependent on the integration of signals that control turnover of ECM (extracellular matrix). Breakdown and endocytosis of collagen, a major component of the ECM, is central to...

Cytoplasmic destruction of p53 by the endoplasmic reticulum-resident ubiquitin ligase ‘Synoviolin'

Yamasaki, Satoshi, Yagishita, Naoko, Sasaki, Takeshi, Nakazawa, Minako, Kato, Yukihiro, Yamadera, Tadayuki, ...

Synoviolin, also called HRD1, is an E3 ubiquitin ligase and is implicated in endoplasmic reticulum -associated degradation. In mammals, Synoviolin plays crucial roles in various physiological and...

Intralobular Distribution of Vitamin A-Storing Lipid Droplets in Hepatic Stellate Cells with Special Reference to Polar Bear and Arctic Fox

Higashi, Nobuyo, Imai, Katsuyuki, Sato, Mitsuru, Sato, Takeya, Kojima, Naosuke, Miura, Mitsutaka, ...

We examined the liver of adult polar bears, arctic foxes, and rats by gold chloride staining, fluorescence microscopy for the detection of autofluorescence of vitamin A, hematoxylin-eosin staining,...

3-D structure of extracellular matrix regulates gene expression in cultured hepatic stellate cells to induce process elongation

Sato, Mitsuru, Sato, Takeya, Kojima, Naosuke, Imai, Katsuyuki, Higashi, Nobuyo, Wang, Da-Ren, ...

HSCs showed myofibroblast-like shapes when cultured on polystyrene surface or on type I collagen-coated surface, whereas HSCs cultured on type I collagen gel were induced to elongate cellular...

Intercellular Adhesive Structures Between Stellate Cells – An Analysis in Cultured Human Hepatic Stellate Cells

Imai, Katsuyuki, Sato, Mitsuru, Sato, Takeya, Kojima, Naosuke, Miura, Mitsutaka, Higashi, Nobuyo, ...

To investigate whether or not hepatic stellate cells can form intercellular junctions with each other, we cultured human stellate cells (LI90) on different kinds of substrata. Intercellular junctions...

Regulation of matrix metallo-proteinase expression by extracellular matrix components in cultured hepatic stellate cells

Wang, Da-Ren, Sato, Mitsuru, Sato, Takeya, Kojima, Naosuke, Higashi, Nobuyo, Senoo, Haruki

Hepatic stellate cells (HSC) changed their morphology and function including production of matrix metalloproteinases (MMPs) in response to extracellular matrix (ECM) component used as a substratum in...