Jensen, Søren A, Vainer, Ben, Kruhøffer, Mogens, Sørensen, Jens B
Abstract Background Microsatellite instability (MSI) refers to mutations in short motifs of tandemly repeated nucleotides resulting from replication errors and deficient mismatch repair (MMR)....
Frequent occurrence of uniparental disomy in colorectal cancer (2007)
Andersen, Claus Lindbjerg, Wiuf, Carsten, Kruhøffer, Mogens, Korsgaard, Marianne, Laurberg, Søren, Ørntoft, Torben Falck
We used SNP arrays to identify and characterize genomic alterations associated with colorectal cancer (CRC). Laser microdissected cancer cells from 15 adenocarinomas were investigated by Affymetrix...
Frequent occurrence of uniparental disomy in colorectal cancer (2006)
Andersen, Claus Lindbjerg, Wiuf, Carsten, Kruhøffer, Mogens, Korsgaard, Marianne, Laurberg, Søren, Rntoft, Torben Falck
We used SNP-arrays to identify and characterize genomic alterations associated with colorectal cancer. Laser microdissected cancer cells from 15 adenocarinomas were investigated by Affymetrix Mapping...
Magnusson, Nils E, Cardozo, Alessandra K, Kruhøffer, Mogens, Eizirik, Decio L, Ørntoft, Torben F, Jensen, Jens L
Abstract Background Type 1 diabetes mellitus (T1DM) is a autoimmune disease caused by a long-term negative balance between immune-mediated beta-cell damage and beta-cell repair/regeneration....
Full genome gene expression analysis of the heat stress response in Drosophila melanogaster (2005)
Jesper G. Sørensen, Morten M. Nielsen, Mogens Kruhøffer, Just Justesen, Volker Loeschcke
Nils E Magnusson, Ra K Cardozo, Mogens Kruhøffer, Decio L Eizirik, Torben F Ørntoft, Jens L Jensen
This is an Open Access article distributed under the terms of the Creative Commons Attribution License
De Breuck, Saskia, Rooman, Ilse, Kruhøffer, Mogens, Orntoft, Torben, ...
Under certain experimental conditions, hepatocytes can arise in the pancreas. It has been suggested that the pancreas retains a source of hepatocyte progenitor cells. However, such cells have not...
Identification of a Core Set of Genes That Signifies Pathways Underlying Cardiac Hypertrophy (2004)
Claes C. Strøm, Mogens Kruhøffer, Steen Knudsen, Frank Stensgaard-Hansen, Torben F. Ørntoft, ...
Although the molecular signals underlying cardiac hypertrophy have been the subject of intense investigation, the extent of common and distinct gene regulation between different forms of cardiac...
Magnusson, Nils E, Cardozo, Alessandra K, Kruhøffer, Mogens, Eizirik, Decio L, Ørntoft, Torben F, Jensen, Jens L
Full genome gene expression analysis of the heat stress response in Drosophila melanogaster
Sørensen, Jesper G., Nielsen, Morten M., Kruhøffer, Mogens, Justesen, Just, Loeschcke, Volker
The availability of full genome sequences has allowed the construction of microarrays, with which screening of the full genome for changes in gene expression is possible. This method can provide a...
Genome-Wide Analysis on Inbreeding Effects on Gene Expression in Drosophila melanogaster
Kristensen, Torsten Nygaard, Sørensen, Peter, Kruhøffer, Mogens, Pedersen, Kamilla Sofie, Loeschcke, Volker
The deleterious consequences of inbreeding, especially in the form of inbreeding depression, are well known. However, little is known about how inbreeding affects genome-wide gene expression. Here,...
Inbreeding by Environmental Interactions Affect Gene Expression in Drosophila melanogaster
Kristensen, Torsten Nygaard, Sørensen, Peter, Pedersen, Kamilla Sofie, Kruhøffer, Mogens, Loeschcke, Volker
Genomewide gene expression patterns were investigated in inbred and noninbred Drosophila melanogaster lines under benign and stressful (high temperature) environmental conditions in a highly...
Full genome gene expression analysis of the heat stress response in Drosophila melanogaster
Sørensen, Jesper G., Nielsen, Morten M., Kruhøffer, Mogens, Justesen, Just, Loeschcke, Volker
The availability of full genome sequences has allowed the construction of microarrays, with which screening of the full genome for changes in gene expression is possible. This method can provide a...
Magnusson, Nils E, Cardozo, Alessandra K, Kruhøffer, Mogens, Eizirik, Decio L, Ørntoft, Torben F, Jensen, Jens L
Genome-Wide Analysis on Inbreeding Effects on Gene Expression in Drosophila melanogaster
Kristensen, Torsten Nygaard, Sørensen, Peter, Kruhøffer, Mogens, Pedersen, Kamilla Sofie, Loeschcke, Volker
The deleterious consequences of inbreeding, especially in the form of inbreeding depression, are well known. However, little is known about how inbreeding affects genome-wide gene expression. Here,...
Inbreeding by Environmental Interactions Affect Gene Expression in Drosophila melanogaster
Kristensen, Torsten Nygaard, Sørensen, Peter, Pedersen, Kamilla Sofie, Kruhøffer, Mogens, Loeschcke, Volker
Genomewide gene expression patterns were investigated in inbred and noninbred Drosophila melanogaster lines under benign and stressful (high temperature) environmental conditions in a highly...
Nielsen, Morten Muhlig, Sørensen, Jesper Givskov, Kruhøffer, Mogens, Justesen, Just, Loeschcke, Volker
The genetic architecture underlying heat resistance remains partly unclear despite the well-documented involvement of heat shock proteins (Hsps). It was previously shown that factors besides Hsps are...
Identification of a Core Set of Genes That Signifies Pathways Underlying Cardiac Hypertrophy
Strøm, Claes C., Kruhøffer, Mogens, Knudsen, Steen, Stensgaard-Hansen, Frank, Jonassen, Thomas E. N., Ørntoft, Torben F., ...
Although the molecular signals underlying cardiac hypertrophy have been the subject of intense investigation, the extent of common and distinct gene regulation between different forms of cardiac...
Isolation of Microarray-Grade Total RNA, MicroRNA, and DNA from a Single PAXgene Blood RNA Tube
Kruhøffer, Mogens, Dyrskjøt, Lars, Voss, Thorsten, Lindberg, Raija L.P., Wyrich, Ralf, Thykjaer, Thomas, ...
We have developed a procedure for isolation of microRNA and genomic DNA in addition to total RNA from whole blood stabilized in PAXgene Blood RNA tubes. The procedure is based on automatic extraction...