Mohamad A. Hussein

Incidence and risk factors of venous thromboembolism (VTD) in patients with amyloidosis (2005)

Srkalovic, Gordan, Cameron, Marte G, Deitcher, Steven R, Kattke-Marchant, Kandice, Hussein, Mohamad A

Abstract Background Coagulation problems in amyloidosis are historically associated with bleeding tendencies (mostly Factor X abnormalities). Increased clotting was observed in isolated cases...

Apoptosis of Multiple Myeloma

Oancea, Marcela, Mani, Aruna, Hussein, Mohamad A, Almasan, Alexandru

Multiple myeloma (MM) is a malignancy of terminally differentiated plasma cells. MM cells localize to the bone marrow, where cell adhesion–mediated autocrine or paracrine activation of various...

Role of Apo2L/TRAIL and Bcl-2-family Proteins in Apoptosis of Multiple Myeloma*

CHEN, QUAN, RAY, SUBRATA, HUSSEIN, MOHAMAD A., SRKALOVIC, GORDAN, ALMASAN, ALEXANDRU

Apo2 Ligand or Tumour Necrosis Factor (TNF)-Related Apoptosis-Inducing Ligand (Apo2L/TRAIL) is a member of the TNF gene superfamily that selectively induces apoptosis in tumor cells of diverse...

G1P3, an IFN-induced survival factor, antagonizes TRAIL-induced apoptosis in human myeloma cells

Cheriyath, Venugopalan, Glaser, Keith B., Waring, Jeffrey F., Baz, Rachid, Hussein, Mohamad A., Borden, Ernest C.

The effectiveness of IFN-α2b for human multiple myeloma has been variable. TRAIL has been proposed to mediate IFN-α2b apoptosis in myeloma. In this study we assessed the effects of IFN-α2b...

CD28-mediated regulation of multiple myeloma cell proliferation and survival

Bahlis, Nizar J., King, Anne M., Kolonias, Despina, Carlson, Louise M., Liu, Hong Yu, Hussein, Mohamad A., ...

Although interactions with bone marrow stromal cells are essential for multiple myeloma (MM) cell survival, the specific molecular and cellular elements involved are largely unknown, due in large...