Ogino, Shuji, Brahmandam, Mohan, Kawasaki, Takako, Kirkner, Gregory J, Loda, Massimo, Fuchs, Charles S
Cyclooxygenase-2 (COX-2) overexpression and mutations of p53 (a known COX-2 regulator) are inversely associated with microsatellite instability—high (MSI-H) and CpG island methylator phenotype...
Ogino, Shuji, Brahmandam, Mohan, Kawasaki, Takako, Kirkner, Gregory J, Loda, Massimo, Fuchs, Charles S
Cyclooxygenase-2 (COX-2) overexpression and mutations of p53 (a known COX-2 regulator) are inversely associated with microsatellite instability—high (MSI-H) and CpG island methylator phenotype...
Sensitive Sequencing Method for KRAS Mutation Detection by Pyrosequencing
Ogino, Shuji, Kawasaki, Takako, Brahmandam, Mohan, Yan, Liying, Cantor, Mami, Namgyal, Chungdak, ...
Both benign and malignant tumors represent heterogenous tissue containing tumor cells and non-neoplastic mesenchymal and inflammatory cells. To detect a minority of mutant KRAS alleles among abundant...
Ogino, Shuji, Kawasaki, Takako, Brahmandam, Mohan, Cantor, Mami, Kirkner, Gregory J., Spiegelman, Donna, ...
Assays to measure DNA methylation, which are important in epigenetic research and clinical diagnostics, typically rely on conversion of unmethylated cytosine to uracil by sodium bisulfite. However,...
Chauhan, Dharminder, Singh, Ajita, Brahmandam, Mohan, Podar, Klaus, Hideshima, Teru, Richardson, Paul, ...
Our recent study demonstrated that a novel proteasome inhibitor NPI-0052 triggers apoptosis in multiple myeloma (MM) cells, and importantly, that is distinct from bortezomib (Velcade) in its chemical...