Fukazawa, Nobuna, Yokoyama, Seisuke, Eiraku, Mototsugu, Kengaku, Mineko, Maeda, Nobuaki
Protein tyrosine phosphatase ζ (PTPζ) is a receptor type protein tyrosine phosphatase that uses pleiotrophin as a ligand. Pleiotrophin inactivates the phosphatase activity of PTPζ, resulting in...
Minimization of exogenous signals in ES cell culture induces rostral hypothalamic differentiation
Wataya, Takafumi, Ando, Satoshi, Muguruma, Keiko, Ikeda, Hanako, Watanabe, Kiichi, Eiraku, Mototsugu, ...
Embryonic stem (ES) cells differentiate into neuroectodermal progenitors when cultured as floating aggregates in serum-free conditions. Here, we show that strict removal of exogenous patterning...