Kanzaki, Hiromitsu, Nouso, Kazuhiro, Miyahara, Koji, Kajikawa, Naoko, Kobayashi, Sayo, Sakakihara, Ichiro, ...
Abstract Introduction Transcatheter arterial chemoembolization has been widely used to treat advanced hepatocellular carcinoma that cannot be treated by local ablation therapies or surgical...
Ishikawa, Shigenao, Inaba, Tomoki, Mizuno, Motowo, Okada, Hiroyuki, Kuwaki, Kenji, Kuzume, Toshiaki, ...
Upper gastrointestinal bleeding is a major adverse event of non-steroidal anti-inflammatory drugs (NSAIDs), and co-administration of proton pump inhibitors and H2 receptor antagonists has been...
Ymadada, Gotaro, Sakamoto, Yuji, Mizuno, Motowo, Kobayashi, Toshinari, Nagashima, Hideo
In electron microscopic observation of a liver biopsy obtained from a hepatitis B surface antigen-positive patient, noncoated core particles were occasionally seen budding into the hepatocytic...
Yamada, Gotaro, Takahashi, Takashi, Mizuno, Motowo, Sakamoto, Yuji, Kaga, Kazumi, Kobayashi, Toshinari, ...
A recently modified method using peroxidase labeled antibodies for light and electron microscopic demonstration of hepatitis B virus (HBV) was applied to the evaluation of hepatitis B surface antigen...
Mizuno, Motowo, Yamada, Gotaro, Sakamoto, Yuzi, Yumoto, Yasuhiro, Nagashima, Hideo
Antibody to hepatitis B core antigen (anti-HBc) was measured by radioimmunoassay using CORAB (Abbott Laboratories) in 10 cases of chronic persistent hepatitis (CPH), 46 cases of chronic aggressive...
Hepatitis B virus associated particles in the bile canaliculus. (2007)
Yamada, Gotaro, Sakamoto, Yuji, Mizuno, Motowo, Kobayashi, Toshinari, Nagashima, Hideo
The liver biopsy specimen from a patient with hepatitis B surface antigen was pbserved by electron microscopy. Dane particles, uncoated core particles and tubular forms were demonstrated in...
Mizuno, Motowo, Yamada, Gotaro, Sakamoto, Yuzi, Nishihara, Takashi, Yumoto, Yasuhiro, Moritsugu, Yasuo, ...
Serum specimens from 12 patients with type A hepatitis were analyzed for immunoglobulin M-type antibody to hepatitis A virus (IgM anti-HA). A recently developed solid-phase radioimmunoassay kit for...
Surgical treatment for Crohn's disease. (2007)
Perdomo, Jose Antonio, Iwagaki, Hiromi, Hizuta, Akio, Mizuno, Motowo, Nakagawa, Hitoshi, Tanaka, Noriaki, ...
The medical records of 16 consecutive patients with Crohn's disease surgically treated in our department from 1978 to 1993 were retrospectively reviewed. The indication for surgery was obstructive...
Nishimoto, Hiroshi, Yamada, Gotaro, Mizuno, Motowo, Tsuji, Takao
We studied the distribution of class 1 and class 2 major histocompatibility complex (MHC) antigens on bile duct epithelial cells in liver from patients with primary biliary cirrhosis (PBC) by an...
Inoue, Hiroshi, Mizuno, Motowo, Uesu, Tokurou, Ueki, Toru, Tsuji, Takao
To clarify the events related to complement-mediated immune responses in human colorectal cancers, we immunohistochemically examined the distribution of decay-accelerating factor (DAF),...
Ikeda, Nobumasa, Mizuno, Motowo, Okada, Hiroyuki, Tomoda, Jun, Tsuji, Takao
To identify diffuse mucosal changes which may precede the development of colorectal cancer and a possible indicator for detecting high-risk populations, we immunohistochemically studied cell-cycle...
Expression of ICAM-I on M cells covering isolated lymphoid follicles of the human colon. (2007)
Ueki, Toru, Mizuno, Motowo, Uesu, Tokurou, Kiso, Takahiko, Tsuji, Takao
To clarify the immunological function of 'M' (microfold or membranous) cells in the large intestine, we examined the expression of intercellular adhesion molecule-1 (ICAM-1) and HLA-class II antigens...
Mikami, Yuichirou, Mizuno, Motowo, Maga, Toshirou, Kihara, Yasuhiro, Yoshinaga, Fumiya, Tanaka, Shouichi, ...
UDP-galactosyltransferase (UDP-Gal-T) is a key enzyme in the synthesis of mucus glycoprotein which plays an important role in gastric mucosal defensive mechanisms. Analysis of gastric UDP-Gal-T...
Okada, Hiroyuki, Mizuno, Motowo, Yamamoto, Kazuhide, Tsuji, Takao
To characterize primary sclerosing cholangitis (PSC) in Japanese patients and its association with inflammatory bowel disease (IBD), 155 reported cases of PSC, including 6 cases of our own, were...
Takahashi, Michiko, Yamada, Gotaro, Miyamoto, Rieko, Doi, Toshihiko, Endo, Hisashi, Nishimoto, Hiroshi, ...
We measured hepatitis C virus antibody titers in 13 patients with chronic hepatitis C to determine whether titration of hepatitis C virus antibody was useful or not, to predict and evaluate the...
Hongo, Toshiki, Tomoda, Jun, Mizuno, Motowo, Maga, Toshirou, Tsuji, Takao
Mucus glycoprotein is one of the major components of gastric mucus which plays an important role in mucosal defensive mechanisms as a mucus-bicarbonate barrier. Analysis of the mucus glycoprotein...
Kanzaki, Kohji, Mizuno, Motowo, Tsuji, Takao
The immunologic mechanisms mediated by anticolon antibodies have been suggested for the injury of colonic mucosa in ulcerative colitis (UC). For the understanding of pathogenetic relevance of the...
Yamada, Gotaro, Mizuno, Motowo, Kinoyama, Shingo, Nishihara, Takashi, Okushin, Hiroaki, Hyodo, Ichinosuke, ...
In 144 cases of hepatocellular carcinoma (HCC), 166 cases of cirrhosis without HCC and 142 cases of chronic hepatitis, we examined HBsAg, anti-HBs and anti-HBc in sera and compared the following...
Ariyoshi, Masanori, MIzuno, Motowo, Morisue, Yoshiko, Shimada, Morizou, Fujita, Shirou, Nasu, Junichirou, ...
We developed a monoclonal antibody (MoAb) (clone 5E8) against an antigen on the bile canalicular membrane of rat hepatocyte. By immunoblotting, MoAb 5E8 detected a band of 110 kD. In this study, we...
Ohya, Shogen, Mizuno, Motowo, Kawada, Mikihiro, Nasu, Junichirou, Okada, Hiroyuki, Shimomura, Hiroyuki, ...
We have previously developed an enzyme-linked immunosorbent assay (ELISA) to measure stool decay-accelerating factor (DAF) and found that stool DAF concentrations were significantly elevated in...
Hirai, Michio, Mizuno, Motowo, Morisue, Yoshiko, Yoshioka, Masao, Shimada, Morizou, Nasu, Junichirou, ...
Anti-idiotype antibodies (Ab2) play an important role in the homeostasis of immune responses and are related to the development and the disease activity of certain autoimmune diseases. The...
Yoshioka, Masao, Mizuno, Motowo, Morisue, Yoshiko, Shimada, Morizou, Hirai, Michio, Nasu, Junichirou, ...
In autoimmune chronic active hepatitis (AIH) and primary biliary cirrhosis (PBC), various autoantibodies including anti-asialoglycoprotein receptor (ASGPR) antibodies have been found in patients'...
Yunoki, Naoko, Yokota, Kenji, Mizuno, Motowo, Kawahara, Yoshiro, Adachi, Masayasu, Okada, Hiroyuki, ...
Infection with Helicobacter pylori induces humoral immune responses against various antigens of the bacterium. Heat shock proteins (hsps) are immunodominant antigens in various diseases including H....
Yunoki, Naoko, Yokota, Kenji, Mizuno, Motowo, Kawahara, Yoshiro, Adachi, Masayasu, Okada, Hiroyuki, ...
Infection with Helicobacter pylori induces humoral immune responses against various antigens of the bacterium. Heat shock proteins (hsps) are immunodominant antigens in various diseases including H....