Walker, Caroline G, Meier, Susanne, Mitchell, Murray D, Roche, John R, Littlejohn, Mathew
Abstract Background Quantitative real-time PCR gene expression results are generally normalised using endogenous control genes. These reference genes should be expressed at a constant level across...
Keelan, Jeffrey A., Wang, Kaye, Chaiworapongsa, Tinnakorn, Romero, Roberto, Mitchell, Murray D., Sato, Timothy A., ...
The placenta and fetal membranes are the site of expression of macrophage inhibitory cytokine (MIC‐1), a member of the transforming growth factor (TGF)‐β superfamily. We hypothesized that...
Collier, Abby C., Tingle, Malcolm D., Paxton, James W., Mitchell, Murray D., Keelan, Jeffrey A.
BACKGROUND: The rationale for this study was to assess the expression, activity and localization of the enzymes uridine diphosphate glucuronosyltransferase (UGT), β-glucuronidase, cytochrome P450 1A...
Prostaglandin biosynthesis in the human fetal adrenal gland: Regulation by glucocorticosteroids
Mitchell, Murray D., Carr, Bruce R., Mason, J. Ian, Simpson, Evan R.
Human fetal adrenal (HFA) tissue was maintained in organ culture to evaluate the biosynthesis of prostaglandins and hormonal regulation of prostaglandin formation by this tissue. The HFA tissue...
The key molecular regulatory mechanisms that govern and coordinate the molecular alterations that underpin the process of human labor remain incompletely understood although enhanced intrauterine...
Prostaglandin biosynthesis in the human fetal adrenal gland: Regulation by glucocorticosteroids
Mitchell, Murray D., Carr, Bruce R., Mason, J. Ian, Simpson, Evan R.
Human fetal adrenal (HFA) tissue was maintained in organ culture to evaluate the biosynthesis of prostaglandins and hormonal regulation of prostaglandin formation by this tissue. The HFA tissue...
The key molecular regulatory mechanisms that govern and coordinate the molecular alterations that underpin the process of human labor remain incompletely understood although enhanced intrauterine...
Autocrine Human Growth Hormone Stimulates Oncogenicity of Endometrial Carcinoma Cells
Pandey, Vijay, Perry, Jo K., Mohankumar, Kumarasamypet M., Kong, Xiang-Jun, Liu, Shu-Min, Wu, Zheng-Sheng, ...
Recent published data have demonstrated elevated levels of human GH (hGH) in endometriosis and endometrial adenocarcinoma. Herein, we demonstrate that autocrine production of hGH can enhance the in...