N. A. Hunt

Improved Procedure for Production of Cytochalasin E and Tremorgenic Mycotoxins by Aspergillus clavatus

Demain, A. L., Hunt, N. A., Malik, V., Kobbe, B., Hawkins, H., Matsuo, K., ...

This report describes an improved procedure for production of cytochalasin E and tremorgens by solid substrate, agitated fermentation of Aspergillus clavatus on pearled barley.

Cell-free ring expansion of penicillin N to deacetoxycephalosporin C by Cephalosporium acremonium CW-19 and its mutants.

Yoshida, M, Konomi, T, Kohsaka, M, Baldwin, J E, Herchen, S, Singh, P, ...

To examine microbiological ring expansion of penicillin N to a cephalosporin, we obtained five mutants of Cephalosporium acremonium blocked in beta-lactam antibiotic biosynthesis from 2500 survivors...

Cell-free conversion of delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine into an antibiotic with the properties of isopenicillin N in Cephalosporium acremonium.

Konomi, T, Herchen, S, Baldwin, J E, Yoshida, M, Hunt, N A, Demain, A L

Cell-free extracts of antibiotic-negative mutants of Cephalosporium acremonium converted delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine (LLD-tripeptide) into an antibiotic that was destroyed by...

Improved Procedure for Production of Cytochalasin E and Tremorgenic Mycotoxins by Aspergillus clavatus

Demain, A. L., Hunt, N. A., Malik, V., Kobbe, B., Hawkins, H., Matsuo, K., ...

This report describes an improved procedure for production of cytochalasin E and tremorgens by solid substrate, agitated fermentation of Aspergillus clavatus on pearled barley.

Cell-free ring expansion of penicillin N to deacetoxycephalosporin C by Cephalosporium acremonium CW-19 and its mutants.

Yoshida, M, Konomi, T, Kohsaka, M, Baldwin, J E, Herchen, S, Singh, P, ...

To examine microbiological ring expansion of penicillin N to a cephalosporin, we obtained five mutants of Cephalosporium acremonium blocked in beta-lactam antibiotic biosynthesis from 2500 survivors...

Cell-free conversion of delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine into an antibiotic with the properties of isopenicillin N in Cephalosporium acremonium.

Konomi, T, Herchen, S, Baldwin, J E, Yoshida, M, Hunt, N A, Demain, A L

Cell-free extracts of antibiotic-negative mutants of Cephalosporium acremonium converted delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine (LLD-tripeptide) into an antibiotic that was destroyed by...