N. A. P. Franken

Analysis of gene expression using gene sets discriminates cancer patients with and without late radiation toxicity (2006)

Svensson, J.P., Stalpers, L.J.A., Franken, N.A.P., Haveman, J., Klein, B., ...

Background Radiation is an effective anti-cancer therapy but leads to severe late radiation toxicity in 5%-10% of patients. Assuming that genetic susceptibility impacts this risk, we hypothesized...

Analysis of Gene Expression Using Gene Sets Discriminates Cancer Patients with and without Late Radiation Toxicity (2006)

Svensson, J.P., Stalpers, L.J.A., Franken, N.A.P., Haveman, J., Klein, B., ...

Clonogenic assay of cells in vitro (2006)

Franken, N.A.P., Rodermond, H.M., Stap, J., Haveman, J., Bree, C. Van

Enhanced activity of deoxycytidine kinase after pulsed low dose rate and single dose gamma irradiation (2006)

Sigmond, J., Haveman, J., Castro Kreder, N., Loves, W.J., Bree, C. Van, Franken, N.A.P., ...

Gadolinium enhances the sensitivity of SW-1573 cells for thermal neutron irradiation (2006)

Franken, N.A.P., Bergs, J., Kok, T.T., Kuperus, R.R.N., Stecher-Rasmussen, F., Haveman, J., ...

Effects of cisplatin and gamma-irradiation on cell survival, the induction of chromosomal aberrations and apoptosis in SW-1573 cells (2006)

Bergs, J., Franken, N.A.P., Cate, R. Ten, Bree, C. Van, Haveman, J.

Time course of enhanced activity of deoxycytidine kinase and thymidine kinase 1 and 2 in cultured human squamous lung carcinoma cells, SW-1573, induced by gamma-irradiation (2006)

Haveman, J., Sigmond, J., Bree, C. Van, Franken, N.A.P., Koedooder, C., Peters, G.J.

Analysis of gene expression using gene sets discriminates cancer patients with and without late radiation toxicity (2006)

Svensson, J.P., Stalpers, L.J.A., Franken, N.A.P., Haveman, J., Klein, B., ...

Mismatch repair proficiency is not required for radioenhancement by gemcitabine (2005)

Bree, C. Van, Rodermond, H.M., Vos, J. De, Haveman, J., Franken, N.A.P.

Cellular Response to Pulsed Low-dose Rate Irradiation in X-ray Sensitive Hamster Mutant Cell Lines (2004)

Castro Kreder, N., Cate, R. Ten, Rodermond, H.M., Bree, C. Van, Franken, N.A.P., Zdzienicka, M.Z.

Cellular response of X-ray sensitive hamster mutant cell lines to gemcitabine, cisplatin and 5-fluorouracil (2004)

Haveman, J., Castro Kreder, N., Rozermond, H.M., Bree, C. Van, Franken, N.A.P., Stalpers, L.J.A., ...

Repair of potentially lethal damage does not depend on functional TP53 in human glioblastoma cells (2004)

Bree, C. Van, Franken, N.A.P., Rodermond, H.M., Stalpers, L.J.A., Haveman, J.

Differential response to radiation of TP53-inactivated cells by overexpression of dominant-negative mutant TP53 or HPVE6 (2004)

Franken, N.A.P., Bree, C. Van, Haveman, J.

Induction of the early response protein EGR-1 in human tumour cells after ionizing radiation is correlated with a reduction of repair of lethal lesions and an increase of repair of sublethal lesions (2004)

Franken, N.A.P., Cate, R. Ten, Bree, C. Van, Haveman, J.

Effects of gemcitabine on cell survival and chromosome aberrations after pulsed low dose-rate irradiation (2004)

Castro Kreder, N., Bree, C. Van, Franken, N.A.P., Haveman, J.

Colour junctions as predictors of radiosensitivity: X-irradiation combined with gemcitabine in a lung carcinoma cell line (2003)

Castro Kreder, N., Bree, C. Van, Franken, N.A.P., Haveman, J.

Importance of TP53 and RB in the repair of potentially lethal damage and induction of color junctions after exposure to ionizing radiation (2002)

Franken, N.A.P., Bree, C. Van, Cate, R. Ten, Oven, C.H. Van, Haveman, J.

Induction of chromosome aberrations in unirradiated chromatin after partial irradiation of a cell nucleus (2002)

Ludwikow, G., Hoebe, R.A., Franken, N.A.P., Darroudi, F., Stap, J., Oven, C.H. Van, ...

Chromosome aberrations detected by FISH and correlation with cell survival after irradiation at various dose-rates and after bromodeoxyuridine radiosensitization (2002)

Castro Kreder, N., Bree, C. Van, Franken, N.A.P., Haveman, J.

Induction of chromosome aberrations in unirradiated chromatin after partial irradiation of a cell nucleus (2002)

Ludwikow, G., Hoebe, R.A., Franken, N.A.P., Darroudi, F., Stap, J., Oven, C.H. Van, ...

Sensitivity to ionizing radiation and chemotherapeutic agents in gemcitabine-resistant human tumor cell lines (2002)

Bree, C. Van, Castro Kreder, N., Loves, W.J., Franken, N.A.P., Peters, G.J., Haveman, J.

Induction of chromosome aberrations in unirradiated chromatin after partial irradiation of a cell nucleus (2002)

Ludwikow, G., Hoebe, R.A., Franken, N.A.P., Darroudi, F., Stap, J., Oven, C.H. Van, ...

Importance of cell proliferative state and potentially lethal damage repair on radiation effectiveness: implications for combined tumor treatments [review] (2001)

Barendsen, G.W., Bree, C. Van, Franken, N.A.P.

Wild-type p53-function is not required for hyperthermia-enhanced cytotoxicity of cisplatin (2001)

Bree, C. Van, Franken, N.A.P., Snel, F.A.M., Haveman, J., Bakker, P.J.M.

Radiosensitization by bromodeoxyuridine and hyperthermia: analysis of linear and quadratic parameters of radiation survival curves of two human tumor cell lines (2001)

Franken, N.A.P., Bree, C. Van, Veltmaat, M.A.T., Rodermond, H.M., Haveman, J., Barendsen, G.W.

BrdUrd-induced radiosensitization of two human tumour cell lines at iso-levels of incorporation (2000)

Franken, N.A.P., Bree, C. Van, Kipp, J.B.A., Rodermond, H.M., Haveman, J., Barendsen, G.W.

A method for the selective irradiation of part of a genome (2000)

Ludwikow, G., Hoebe, R.A., Franken, N.A.P., Oven, C.H. Van, Stap, J., Aten, J.A.

Myocardial enzyme activities in plasma after whole-heart irradiation in rats (2000)

Franken, N.A.P., Strootman, E., Hollaar, L., Laarse, A. Van Der, Wondergem, J.

The effect of p53-function on the sensitivity to paclitaxel with or without hyperthermia in human colorectal carcinoma cells (2000)

Bree, C. Van, Savonije, J.H., Franken, N.A.P., Haveman, J., Bakker, P.J.M.

The effect of p53-function on the sensitivity to paclitaxel with or without hyperthermia in human colorectal carcinoma cells (2000)

Bree, C. Van, Savonije, J.H., Franken, N.A.P., Haveman, J., Bakker, P.J.M.

A method for the selective irradiation of part of a genome (2000)

Ludwikow, G., Hoebe, R.A., Franken, N.A.P., Oven, C.H. Van, Stap, J., Aten, J.A.

A method for the selective irradiation of part of a genome (2000)

Ludwikow, G., Hoebe, R.A., Franken, N.A.P., Oven, C.H. Van, Stap, J., Aten, J.A.

The effect of p53-function on the sensitivity to paclitaxel with or without hyperthermia in human colorectal carcinoma cells (2000)

Bree, C. Van, Savonije, J.H., Franken, N.A.P., Haveman, J., Bakker, P.J.M.

Increased chromosome exchange frequencies in iodo-deoxyuridine-sensitized human SW-1573 cells after y-irradiation (1999)

Franken, N.A.P., Bree, C. Van, Veltmaat, M.A.T., Ludwikow, G., Kipp, J.B.A., Barendsen, G.W.

Correlation between cell reproductive death and chromosome aberrations assessed by FISH for low and ahigh doses radiation and sensitization by iodo-deoxyuridine in human SW-1573 cells (1999)

Franken, N.A.P., Ruurs, P., Ludwikow, G., Bree, C. Van, Kipp, J.B.A., Darroudi, F., ...

Inactivation of p53 and of pRb protects human colorectal carcinoma cells against hyperthermia-induced cytotoxicity and apoptosis (1999)

Bree, C. Van, Maat, B. Van Der, Ceha, H.M., Franken, N.A.P., Haveman, J., Bakker, P.J.M.

Inactivation of p53 and of pRb protects human colorectal carcinoma cells against hyperthermia-induced cytotoxicity and apoptosis (1999)

Bree, C. Van, Maat, B. Van Der, Ceha, H.M., Franken, N.A.P., Haveman, J., Bakker, P.J.M.

Increased chromosome exchange frequencies in iodo-deoxyuridine-sensitized human SW-1573 cells after y-irradiation (1999)

Franken, N.A.P., Bree, C. Van, Veltmaat, M.A.T., Ludwikow, G., Kipp, J.B.A., Barendsen, G.W.

Correlation between cell reproductive death and chromosome aberrations assessed by FISH for low and ahigh doses radiation and sensitization by iodo-deoxyuridine in human SW-1573 cells (1999)

Franken, N.A.P., Ruurs, P., Ludwikow, G., Bree, C. Van, Kipp, J.B.A., Darroudi, F., ...

Variability of enhancement ratios for IdUrd-radiosensitisation, explained by LQ analysis of dose-response relations for cell reproductive death and chromosome exchange frequences (1999)

Franken, N.A.P., Bree, C. Van, Kipp, J.B.A., Barendsen, G.W.

Increased chromosome exchange frequencies in iodo-deoxyuridine-sensitized human SW-1573 cells after y-irradiation (1999)

Franken, N.A.P., Bree, C. Van, Veltmaat, M.A.T., Ludwikow, G., Kipp, J.B.A., Barendsen, G.W.

Correlation between cell reproductive death and chromosome aberrations assessed by FISH for low and ahigh doses radiation and sensitization by iodo-deoxyuridine in human SW-1573 cells (1999)

Franken, N.A.P., Ruurs, P., Ludwikow, G., Bree, C. Van, Kipp, J.B.A., Darroudi, F., ...

Inactivation of p53 and of pRb protects human colorectal carcinoma cells against hyperthermia-induced cytotoxicity and apoptosis (1999)

Bree, C. Van, Maat, B. Van Der, Ceha, H.M., Franken, N.A.P., Haveman, J., Bakker, P.J.M.

Additive effect of concomittent multiple low-dose doxorubicin and thoracic irradiation on ex vivo cardiac performance of the rat heart (1998)

Wondergem, J., Franken, N.A.P., Chin, A., Leer, J.W.H.

Comparison of in vivo cardiac function with ex vivo cardiac performance of the rat heart after thoracic irradiation (1997)

Franken, N.A.P., Camps, J.A.J., Laarse, A. Van Der, Pauwels, E.K.J., Wondergem, J.

Radiosensitization by iodo-deoxyuridine in cultured SW-1573 human lung tumor cells: effects on alfa and beta of the linear-quadratic model (1997)

Franken, N.A.P., Bree, C. Van, Streefkerk, J.O., Rodermond, H.M., Kipp, J.B.A., ...

Modification of potentially lethal damage in irradiated Chinese hamster V79 cells after incorporation of halogenated pyrimidines (1997)

Franken, N.A.P., Bree, C. Van, Kipp, J.B.A., Barendsen, G.W.

Hyperthermia and incorporation of halogenated pyrimidines: radiosensitization in cultured rodent and humor tumor cells (1997)

Bree, C. Van, Franken, N.A.P., Bakker, P.J.M., Klomp-Tukker, L.J., Barendsen, G.W., Kipp, J.B.A.

Protection of myocytes against free radical-induced damage by accelerated turnover of the glutathione redox cycle (1995)

LE, C. T., HOLLAAR, L., FRANKEN, N. A. P., WONDERGEM, J., ...

The primary defence mechanism of myocytes against peroxides and peroxide-derived peroxyl and alkoxyl radicals is the glutathione redox cycle. The purpose of the present study was to increase the...