Tissue factor, angiogenesis and tumour progression (2008)
Bluff, J., Brown, N., Reed, M., Staton, C.
Tissue factor, the primary initiator of the coagulation cascade, maintains vascular integrity in response to injury. It is now recognised that, in addition to the role as a procoagulant activator,...
This paper describes the organisation, preparation and delivery of a major project, namely, a national roundtable conference on assessment, in the context of a wider project involving the development...
Assessment in the Professional Experience Context (2008)
Professional Experience is a key component of teacher education programs, bringing together the different disciplines of Education into a real-world setting. Helping pre-service teachers see theory...
Endostatin gene variation and protein levels in breast cancer susceptibility and severity (2007)
Balasubramanian, S., Cross, S., Globe, J., Cox, A., Brown, N., Reed, M.
BACKGROUND: Endostatin is a potent endogenous anti-angiogenic agent which inhibits tumour growth. A non-synonymous coding polymorphism in the Endostatin gene is thought to affect Endostatin activity....
Brown, a Senior Research Fellow, under the supervision of Wright, is lead author. This work helped underpin the recently successful 4M (EPSRC) funding bid, regarding building monitoring.
Effects of combined treatment with Zometa and Taxol on endothelial cells in vitro (2006)
Michailidou, M., Brown, N., Coleman, R.E., Holen, I.
Zoledronic acid (ZOL) (Novartis Pharma, Basel, Switzerland) is a N-containing bisphosphonate currently used in the treatment of osteoporosis and tumour-induced bone disease in a wide range of solid...
Azmy, I, Balasubramanian, S., Wilson, A., Stephenson, T., Cox, A., Brown, N., ...
INTRODUCTION: Genetic polymorphisms in the promoter region of the tumour necrosis factor (TNF) gene can regulate gene expression and have been associated with inflammatory and malignant conditions....
Brown, J., Walter, T. S., Carter, L., Abrescia, N. G. A., Aricescu, A. R., Batuwangala, T. D., ...
An initial tranche of results from day-to-day use of a robotic system for setting up 100 nl-scale vapour-diffusion sitting-drop protein crystallizations has been surveyed. The database of over 50...
Brown, J., Walter, T. S., Carter, L., Abrescia, N. G. A., Aricescu, A. R., Batuwangala, T. D., ...
An initial tranche of results from day-to-day use of a robotic system for setting up 100 nl-scale vapour-diffusion sitting-drop protein crystallizations has been surveyed. The database of over 50...
Contribution of bradykinin to the cardioprotective effects of ACE inhibitors (2003)
Murphey, L., Vaughan, D., Brown, N.
Bradykinin, through its B2 receptor, stimulates endothelial release of a number of vasodilators, such as nitric oxide, prostacyclin, and endothelium-derived hyperpolarizing factor (EDHF)....
Stochastic Modelling of GPS Phase Observationsfor Improved Quality Estimation (2002)
Brown, N., Kealy, A., Williamson, I. P.
Data quality information has been recognised as essential in assessing the fitness for use of anyspatial dataset, and fundamental to enabling efficient and effective data integration through...
Quality Control and Integrity Monitoring of the Victorian GPS Reference Station Network (2002)
Brown, N., Kealy, A., Millner, J., Ramm, P., Williamson, I. P.
Permanent GPS reference station networks are being established worldwide followingthe establishment of GPS as a primary means for spatial data acquisition. Often thesenetworks are used to augment the...
Quality Control and Integrity Monitoring of the Victorian GPS Reference Station Network (2002)
Brown, N., Kealy, A., Millner, J., Ramm, P., Williamson, I. P.
Permanent GPS reference station networks are being established worldwide followingthe establishment of GPS as a primary means for spatial data acquisition. Often thesenetworks are used to augment the...
Stochastic Modelling of GPS Phase Observationsfor Improved Quality Estimation (2002)
Brown, N., Kealy, A., Williamson, I. P.
Data quality information has been recognised as essential in assessing the fitness for use of anyspatial dataset, and fundamental to enabling efficient and effective data integration through...
Packham, C., Gray, D., Silcocks, P., Brown, N., Melville, M., Hampton, J.
Aims To examine the survival of patients admitted with a suspected acute myocardial infarction in whom the diagnosis was not confirmed (‘possible myocardial infarction’). Methods and Results A...
Brown, N, Melville, M, Gray, D, Young, T, Skene, AM, Hampton, JR
Background.Health-related quality of life, an important outcome measure in health interventions, can readily be assessed by questionnaire. Two widely evaluated examples are the Short Form 36 (SF-36)...
Re-defining native woodland (1997)
The term ‘native’ is widely used to refer to a small number of British tree species and naturally regenerating woodland. This paper proposes that the concept is rooted in an out-dated...
Melon, M, Brown, N, Castagnede, B
The acoustic wave most commonly transmitted and detected in the high-porosity absorbent materials used in noise control is generally the air-borne slow compressional wave. In a new experiment, the...
REID, D. M., KENNEDY, N. S. J., SMITH, M. A., NICOLL, J., BROWN, N., TOTHILL, P., ...
The annual rate of bone loss in rheumatoid arthritis (RA) and primary generalized osteoarthrosis (PGOA) was determined by measurement of total body calcium (TBCa). The mean annual rate of bone loss...
Kakolyris, S, Fox, S B, Koukourakis, M, Giatromanolaki, A, Brown, N, Leek, R D, ...
Angiogenesis, the formation of new vessels, has been demonstrated to be an indicator of prognosis in breast cancer patients. The extent of differentiation of the tumour vessels may affect access of...
Schönfeld, D., Matschiner, G., Chatwell, L., Trentmann, S., Gille, H., Hülsmeyer, M., ...
Biomolecular reagents that enable the specific molecular recognition of proteins play a crucial role in basic research as well as medicine. Up to now, antibodies (immunoglobulins) have been widely...