N. C. Nelson

Detection of all single-base mismatches in solution by chemiluminescence.

Nelson, N C, Hammond, P W, Matsuda, E, Goud, A A, Becker, M M

A rapid in-solution method for the detection of all 12 single-base mismatches is described. The technique is based on the hybridization protection assay (HPA) format that utilizes oligonucleotide...

Advantages of 2'-O-methyl oligoribonucleotide probes for detecting RNA targets.

Majlessi, M, Nelson, N C, Becker, M M

We have compared various kinetic and melting properties of oligoribonucleotide probes containing 2'-O-methylnucleotides or 2'-deoxynucleotides with regard to their use in assays for the detection of...

Detection of all single-base mismatches in solution by chemiluminescence.

Nelson, N C, Hammond, P W, Matsuda, E, Goud, A A, Becker, M M

A rapid in-solution method for the detection of all 12 single-base mismatches is described. The technique is based on the hybridization protection assay (HPA) format that utilizes oligonucleotide...

Advantages of 2'-O-methyl oligoribonucleotide probes for detecting RNA targets.

Majlessi, M, Nelson, N C, Becker, M M

We have compared various kinetic and melting properties of oligoribonucleotide probes containing 2'-O-methylnucleotides or 2'-deoxynucleotides with regard to their use in assays for the detection of...

Vitreon, a short-term vitreoretinal tamponade.

Blinder, K J, Peyman, G A, Desai, U R, Nelson, N C, Alturki, W, Paris, C L

This investigation of the liquid perfluorocarbon, perfluorophenanthrene (Vitreon), establishes its safety and efficacy as a short-term vitreoretinal tamponade. We utilised Vitreon as an...