Katsumata, N., Watanabe, T., Minami, H., Aogi, K., Tabei, T., Sano, M., ...
Background: This randomized, multicenter, phase III trial compared doxorubicin plus cyclophosphamide (AC), single-agent docetaxel (D), and an alternating regimen of AC and docetaxel (AC–D) as...
Katsumata, N., Tsunematsu, R., Tanaka, K., Terashima, Y., Ogita, S., Hoshiai, H., ...
Background: This phase II study was conducted to evaluate the efficacy and toxicity of docetaxel in Japanese patients with advanced ovarian cancer. Patients and methods: Docetaxel was administered at...
Cerebral metastasis in patients with uterine cervical cancer (1998)
Ikeda, S, Yamada, T, Katsumata, N, Hida, K, Tanemura, K, Tsunematu, R, ...
Tang, X, Tanemura, K, Ye, W, Ohmi, K, Tsunematsu, R, Yamada, T, ...
Ando, M., Watanabe, T., Sasaki, Y., Ying, D. F., Omuro, Y., Katsumata, N., ...
To determine the maximum-tolerated doses (MTDs), the dose-limiting toxicities (DLTs) and the recommended doses for further trials of docetaxel in combination with a 5-day continuous infusion of...
Katsumata, N, Noda, K, Nozawa, S, Kitagawa, R, Nishimura, R, Yamaguchi, S, ...
The purpose of this study was to determine whether docetaxel has antitumour activity in patients with advanced or recurrent endometrial carcinoma. Chemotherapy-naïve or previously treated patients...
Tokuda, Y, Watanabe, T, Omuro, Y, Ando, M, Katsumata, N, Okumura, A, ...
We conducted a phase I pharmacokinetic dose escalation study of a recombinant humanized anti-p185HER2 monoclonal antibody (MKC-454) in 18 patients with metastatic breast cancer refractory to...
Docetaxel: an alternative taxane in ovarian cancer
The taxanes paclitaxel and docetaxel are potent chemotherapeutic agents that block tubulin depolymerisation, leading to the inhibition of microtubule dynamics and cell cycle arrest. Although...