N. Luisa Hiller

What makes pathogens pathogenic (2008)

Ehrlich, Garth D, Hiller, N Luisa, Hu, Fen

Abstract Metazoans contain multiple complex microbial ecosystems in which the balance between host and microbe can be tipped from commensalism to pathogenicity. This transition is likely to depend...

An erythrocyte vesicle protein exported by the malaria parasite promotes tubovesicular lipid import from the host cell surface. (2008)

Tamez, Pamela A., Bhattacharjee, Souvik, Van Ooij, Christiaan, Hiller, N. Luisa, Llin S, Manuel, Balu, Bharath, ...

Plasmodium falciparum is the protozoan parasite that causes the most virulent of human malarias. The blood stage parasites export several hundred proteins into their host erythrocyte that underlie...

The malaria secretome: from algorithms to essential function in blood stage infection. (2008)

Van Ooij, Christiaan, Tamez, Pamela, Bhattacharjee, Souvik, Hiller, N. Luisa, Harrison, Travis, Liolios, Konstantinos, ...

The malaria agent Plasmodium falciparum is predicted to export a "secretome" of several hundred proteins to remodel the host erythrocyte. Prediction of protein export is based on the presence of an...

Virulence phenotypes of low-passage clinical isolates of Nontypeable Haemophilus influenzaeassessed using the chinchilla lanigermodel of otitis media (2007)

Buchinsky, Farrel J, Forbes, Michael L, Hayes, Jay D, Shen, Kai, Ezzo, Suzanne, Compliment, James, ...

Abstract Background The nontypeable Haemophilus influenzae (NTHi) are associated with a spectrum of respiratory mucosal infections including: acute otitis media (AOM); chronic otitis media with...

The Malarial Host-Targeting Signal Is Conserved in the Irish Potato Famine Pathogen (2006)

Souvik Bhattacharjee, N. Luisa Hiller, Konstantinos Liolios, Joe Win, Thirumala-Devi Kanneganti, Carolyn Young, ...

Animal and plant eukaryotic pathogens, such as the human malaria parasite Plasmodium falciparum and the potato late blight agent Phytophthora infestans, are widely divergent eukaryotic microbes. Yet...

Functional bioinformatic studies in erythrocyte remodeling by malaria parasites [electronic resource]. (2005)

Hiller, N. Luisa.

The human malaria parasite Plasmodium falciparum infects and develops within erythrocytes. This stage of infection is responsible for all the symptoms and pathologies of disease. In the...

Vacuolar uptake of host components, and a role for cholesterol and sphingomyelin in malarial infection

Lauer, Sabine, VanWye, Jeffrey, Harrison, Travis, McManus, Heather, Samuel, Benjamin U., Hiller, N.Luisa, ...

Erythrocytes, which are incapable of endocytosis or phagocytosis, can be infected by the malaria parasite Plasmodium falciparum. We find that a transmembrane protein (Duffy),...

The Malarial Host-Targeting Signal Is Conserved in the Irish Potato Famine Pathogen

Bhattacharjee, Souvik, Hiller, N. Luisa, Liolios, Konstantinos, Win, Joe, Kanneganti, Thirumala-Devi, Young, Carolyn, ...

Animal and plant eukaryotic pathogens, such as the human malaria parasite Plasmodium falciparum and the potato late blight agent Phytophthora infestans, are widely divergent eukaryotic microbes. Yet...

Vacuolar uptake of host components, and a role for cholesterol and sphingomyelin in malarial infection

Lauer, Sabine, VanWye, Jeffrey, Harrison, Travis, McManus, Heather, Samuel, Benjamin U., Hiller, N.Luisa, ...

Erythrocytes, which are incapable of endocytosis or phagocytosis, can be infected by the malaria parasite Plasmodium falciparum. We find that a transmembrane protein (Duffy),...

The Malarial Host-Targeting Signal Is Conserved in the Irish Potato Famine Pathogen

Bhattacharjee, Souvik, Hiller, N. Luisa, Liolios, Konstantinos, Win, Joe, Kanneganti, Thirumala-Devi, Young, Carolyn, ...

Animal and plant eukaryotic pathogens, such as the human malaria parasite Plasmodium falciparum and the potato late blight agent Phytophthora infestans, are widely divergent eukaryotic microbes. Yet...

Comparative Genomic Analyses of Seventeen Streptococcus pneumoniae Strains: Insights into the Pneumococcal Supragenome▿ †

Hiller, N. Luisa, Janto, Benjamin, Hogg, Justin S., Boissy, Robert, Yu, Susan, Powell, Evan, ...

The distributed-genome hypothesis (DGH) states that pathogenic bacteria possess a supragenome that is much larger than the genome of any single bacterium and that these pathogens utilize genetic...

The Malaria Secretome: From Algorithms to Essential Function in Blood Stage Infection

Van Ooij, Christiaan, Tamez, Pamela, Bhattacharjee, Souvik, Hiller, N. Luisa, Harrison, Travis, Liolios, Konstantinos, ...

The malaria agent Plasmodium falciparum is predicted to export a “secretome” of several hundred proteins to remodel the host erythrocyte. Prediction of protein export is based on the presence of...

What makes pathogens pathogenic

Ehrlich, Garth D, Hiller, N Luisa, Hu, Fen Ze

A review of the evolution of microbial pathogenicity in the context of the 'symbiome' of microbes and their multicellular hosts.

An Erythrocyte Vesicle Protein Exported by the Malaria Parasite Promotes Tubovesicular Lipid Import from the Host Cell Surface

Tamez, Pamela A., Bhattacharjee, Souvik, Van Ooij, Christiaan, Hiller, N. Luisa, Llinás, Manuel, Balu, Bharath, ...

Plasmodium falciparum is the protozoan parasite that causes the most virulent of human malarias. The blood stage parasites export several hundred proteins into their host erythrocyte that underlie...