Okahashi, N, Yamamoto, M, Vancott, J L, Chatfield, S N, Roberts, M, Bluethmann, H, ...
Mucosal immunoglobulin A (IgA) responses are often associated with Th2-type cells and derived cytokines, and interleukin-4 (IL-4) knockout (IL-4-/-) mice with impaired Th2 cells respond poorly to...
Takahashi, I, Okahashi, N, Hamada, S
Mutans streptococci have been shown to give rise to variants in terms of expression of surface protein antigens by repeated subculturing of the organisms, which in turn induces changes in colonial...
Takahashi, I, Matsushita, K, Nisizawa, T, Okahashi, N, Russell, M W, Suzuki, Y, ...
The immune responses to a cell surface protein antigen (PAc) of Streptococcus mutans and a peptide corresponding to residues 301 to 319 of the protein antigen [PAc(301-319)] in various strains of...
Complete nucleotide sequence of the gene for a surface protein antigen of Streptococcus sobrinus.
Tokuda, M, Okahashi, N, Takahashi, I, Nakai, M, Nagaoka, S, Kawagoe, M, ...
The complete nucleotide sequence of the gene for a cell surface protein antigen (SpaA) of Streptococcus sobrinus MT3791 (serotype g) was determined. The spaA gene consisted of 4,698 bp and coded for...
Koga, T, Okahashi, N, Takahashi, I, Kanamoto, T, Asakawa, H, Iwaki, M
The pac gene of the serotype c strain Streptococcus mutans MT8148 encodes a cell surface protein antigen (PAc) of approximate 190 kilodaltons. The serotype c strain S. mutans GS-5 does not produce...
Koga, T, Nishihara, T, Fujiwara, T, Nisizawa, T, Okahashi, N, Noguchi, T, ...
Lipopolysaccharides (LPSs) were isolated from Bacteroides gingivalis and Escherichia coli by the phenol-water and butanol-water procedures. The phenol-water-extracted LPS from B. gingivalis 381 was...
Okahashi, N, Asakawa, H, Koga, T, Masuda, N, Hamada, S
Streptococcus mutans MT6801 , MT6861 , and MT6879 , which form large mucoid colonies on mitis salivarius agar, were isolated from a mother and her two daughters. These isolates were identified as...
Koga, T, Okahashi, N, Yamamoto, T, Mizuno, J, Inoue, M, Hamada, S
Cell wall carbohydrate antigen of Streptococcus sanguis ATCC 10557 (serotype II/biotype B) was extracted from purified cell walls by treatment with 5% trichloroacetic acid at 4 degrees C for 8 h. The...
Saliva-binding region of Streptococcus mutans surface protein antigen.
Nakai, M, Okahashi, N, Ohta, H, Koga, T
A 190-kDa surface protein antigen (PAc) of Streptococcus mutans binds to human salivary components. For detection of specific binding of the PAc protein to human salivary components, a simple...
Okahashi, N, Takahashi, I, Nakai, M, Senpuku, H, Nisizawa, T, Koga, T
A surface protein antigen (PAc) of Streptococcus mutans with a molecular mass of 190 kDa is considered to play an important role in the initial attachment of this streptococcus to the tooth surface....
Iwaki, M, Okahashi, N, Takahashi, I, Kanamoto, T, Sugita-Konishi, Y, Aibara, K, ...
A recombinant Streptococcus lactis strain which carries the structural gene for a surface protein antigen (PAc) of 190,000 daltons from Streptococcus mutans serotype c was constructed for development...
Non-cariogenicity of the disaccharide palatinose in experimental dental caries of rats.
Ooshima, T, Izumitani, A, Sobue, S, Okahashi, N, Hamada, S
The caries-inducing activity of palatinose (isomaltulose, alpha-D-glucopyranosyl-1,6-fructose) was examined in in vitro and in vivo experiments, comparing it with other carbohydrates. When...
Okahashi, N, Koga, T, Akada, H, Hamada, S
The serotype-specific antigen of Streptococcus sanguis ST3 (serotype I, biotype A) was extracted, chromatographically purified, and characterized by immunological and chemical methods. The antigen...
Okahashi, N, Yamamoto, M, Vancott, J L, Chatfield, S N, Roberts, M, Bluethmann, H, ...
Mucosal immunoglobulin A (IgA) responses are often associated with Th2-type cells and derived cytokines, and interleukin-4 (IL-4) knockout (IL-4-/-) mice with impaired Th2 cells respond poorly to...
Takahashi, I, Okahashi, N, Hamada, S
Mutans streptococci have been shown to give rise to variants in terms of expression of surface protein antigens by repeated subculturing of the organisms, which in turn induces changes in colonial...
Takahashi, I, Matsushita, K, Nisizawa, T, Okahashi, N, Russell, M W, Suzuki, Y, ...
The immune responses to a cell surface protein antigen (PAc) of Streptococcus mutans and a peptide corresponding to residues 301 to 319 of the protein antigen [PAc(301-319)] in various strains of...
Complete nucleotide sequence of the gene for a surface protein antigen of Streptococcus sobrinus.
Tokuda, M, Okahashi, N, Takahashi, I, Nakai, M, Nagaoka, S, Kawagoe, M, ...
The complete nucleotide sequence of the gene for a cell surface protein antigen (SpaA) of Streptococcus sobrinus MT3791 (serotype g) was determined. The spaA gene consisted of 4,698 bp and coded for...
Koga, T, Okahashi, N, Takahashi, I, Kanamoto, T, Asakawa, H, Iwaki, M
The pac gene of the serotype c strain Streptococcus mutans MT8148 encodes a cell surface protein antigen (PAc) of approximate 190 kilodaltons. The serotype c strain S. mutans GS-5 does not produce...
Koga, T, Nishihara, T, Fujiwara, T, Nisizawa, T, Okahashi, N, Noguchi, T, ...
Lipopolysaccharides (LPSs) were isolated from Bacteroides gingivalis and Escherichia coli by the phenol-water and butanol-water procedures. The phenol-water-extracted LPS from B. gingivalis 381 was...
Okahashi, N, Asakawa, H, Koga, T, Masuda, N, Hamada, S
Streptococcus mutans MT6801 , MT6861 , and MT6879 , which form large mucoid colonies on mitis salivarius agar, were isolated from a mother and her two daughters. These isolates were identified as...
Koga, T, Okahashi, N, Yamamoto, T, Mizuno, J, Inoue, M, Hamada, S
Cell wall carbohydrate antigen of Streptococcus sanguis ATCC 10557 (serotype II/biotype B) was extracted from purified cell walls by treatment with 5% trichloroacetic acid at 4 degrees C for 8 h. The...
Saliva-binding region of Streptococcus mutans surface protein antigen.
Nakai, M, Okahashi, N, Ohta, H, Koga, T
A 190-kDa surface protein antigen (PAc) of Streptococcus mutans binds to human salivary components. For detection of specific binding of the PAc protein to human salivary components, a simple...
Okahashi, N, Takahashi, I, Nakai, M, Senpuku, H, Nisizawa, T, Koga, T
A surface protein antigen (PAc) of Streptococcus mutans with a molecular mass of 190 kDa is considered to play an important role in the initial attachment of this streptococcus to the tooth surface....
Iwaki, M, Okahashi, N, Takahashi, I, Kanamoto, T, Sugita-Konishi, Y, Aibara, K, ...
A recombinant Streptococcus lactis strain which carries the structural gene for a surface protein antigen (PAc) of 190,000 daltons from Streptococcus mutans serotype c was constructed for development...
Non-cariogenicity of the disaccharide palatinose in experimental dental caries of rats.
Ooshima, T, Izumitani, A, Sobue, S, Okahashi, N, Hamada, S
The caries-inducing activity of palatinose (isomaltulose, alpha-D-glucopyranosyl-1,6-fructose) was examined in in vitro and in vivo experiments, comparing it with other carbohydrates. When...
Okahashi, N, Koga, T, Akada, H, Hamada, S
The serotype-specific antigen of Streptococcus sanguis ST3 (serotype I, biotype A) was extracted, chromatographically purified, and characterized by immunological and chemical methods. The antigen...