Ambrose, N. S., Johnson, Margaret, Burdon, D. W., Keighley, M. R.B.
The influence of a single intravenous dose of antibiotic on faecal flora and the emergence of Clostridiwn digfficile was studied in volunteers. Seventy-eight volunteers (13 groups of 6 receiving 5...
Evaluation of mezlocillin in elective gastrointestinal surgery (1983)
Keighley, M. R. B., Ambrose, N. S., Morris, D. L., Burdon, D. W.
We report the interim results of two trials to evaluate the place of mezlocillin in elective intestinal operations. Sixity-four operations for gastro-oesophageal disease have been performed where...
The penetration of cefoxitin into peritoneal fluid (1981)
Wise, R., Donovan, I. A., Ambrose, N. S., Allcock, J. E.
Twenty-five patients undergoing elective abdominal surgery received 2 g cefoxitin iv at varying times before surgery. A pre-weighed sterile 13 mm diameter assay disc was placed on the peritoneal...
Obscure bleeding from the small bowel.
Brearley, S, Ambrose, N S, Silverman, S, Hawker, P C, Dorricott, N J, Keighley, M R
Ambrose, N S, Hares, M M, Alexander-Williams, J, Keighley, M R
Two hundred and sixty eight patients with haemorrhoids were allocated at random to treatment by either photocoagulation (group 1, n=141) or rubber band ligation (group 2, n=127) and followed up for...
Obscure bleeding from the small bowel.
Brearley, S, Ambrose, N S, Silverman, S, Hawker, P C, Dorricott, N J, Keighley, M R
Ambrose, N S, Hares, M M, Alexander-Williams, J, Keighley, M R
Two hundred and sixty eight patients with haemorrhoids were allocated at random to treatment by either photocoagulation (group 1, n=141) or rubber band ligation (group 2, n=127) and followed up for...
Clinical impact of colectomy and ileorectal anastomosis in the management of Crohn's disease.
Ambrose, N S, Keighley, M R, Alexander-Williams, J, Allan, R N
We report the outcome of 63 consecutive patients with Crohn's colitis treated by colectomy and ileorectal anastomosis between 1951-1981. There were no operative deaths. Serious postoperative...
Peri-operative modulation of cellular immunity in patients with colorectal cancer.
Nichols, P H, Ramsden, C W, Ward, U, Trejdosiewicz, L K, Ambrose, N S, Primrose, J N
The peri-operative cellular immune response is depressed in patients with gastrointestinal cancer, a factor which may facilitate malignant dissemination. We have investigated the effects of...
A case of Sister Mary Joseph nodule associated with primary gastric lymphoma.
Hopton, B. P., Wyatt, J. I., Ambrose, N. S.
The Sister Mary Joseph nodule is a peri-umbilical metastasis most commonly found with adenocarcinomas of the gastrointestinal tract and ovary. It was first described 140 years ago but has not...
An aid to the assessment of bowel preparation prior to colonic resection.
Ambrose, N. S., Keighley, M. R.
The removal of solid and liquid faeces from the colon is a prerequisite for safe colonic resection. Previous studies attempting to quantify evacuation of the colon have relied on a subjective opinion...
Brearley, S., Hawker, P. C., Dorricott, N. J., Lee, J. R., Ambrose, N. S., Silverman, S. H., ...
Thirty-seven patients who had had either a colonoscopy or a selective mesenteric angiogram while being investigated for severe or persistent gastrointestinal bleeding of obscure origin were reviewed....
Enterovesical fistulas in Crohn's disease.
Heyen, F., Ambrose, N. S., Allan, R. N., Dykes, P. W., Alexander-Williams, J., Keighley, M. R.
A total of 19 enterovesical fistulas were recorded in a series of 799 patients with Crohn's disease (2.4%). The origin of the fistulas was: ileum (9), colon (6) and four were complex involving the...
Selective salvage surgery in gastrointestinal and gynaecological cancer.
Allum, W. H., Ambrose, N. S., Fielding, J. W., Chan, K. K.
The role of reoperation with intent to excise locally recurrent disease has been evaluated in a selected group of 64 patients originally treated for primary gastrointestinal or gynaecological cancer....
Serum concentrations of soluble adhesion molecules in patients with colorectal cancer.
Velikova, G., Banks, R. E., Gearing, A., Hemingway, I., Forbes, M. A., Preston, S. R., ...
The concentrations of the soluble adhesion molecules E-cadherin, E-selectin, intercellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1) were investigated in 48 patients...
Velikova, G., Banks, R. E., Gearing, A., Hemingway, I., Forbes, M. A., Preston, S. R., ...
The concentrations of the soluble adhesion molecules E-cadherin, E-selectin, intercellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1) were investigated in 45 patients...