Recommendations of the 2006 Human Variome Project meeting (2007)
Cotton, R.G.H., Appelbe, W., Auerbach, A.D., Becker, K., Bodmer, W., Boone, D.J., ...
Lists of variations in genomic DNA and their effects have been kept for some time and have been used in diagnostics and research. Although these lists have been carefully gathered and curated, there...
Radiation hybrid maps of Medaka chromosomes LG 12, 17, and 22 (2007)
Su, F., Osada, Y., Ekker, M., Chevrette, M., Shimizu, A., Asakawa, S., ...
The Medaka is an excellent genetic system for studies of vertebrate development and disease and environmental and evolutionary biology studies. To facilitate the mapping of markers or the cloning of...
Somatic Mutations of the HER2 Kinase Domain in Lung Adenocarcinomas (2005)
Shigematsu, H., Takahashi, T., Nomura, M., Majmudar, K., Suzuki, M., Lee, H., ...
Mutations in the epidermal growth factor receptor gene (EGFR) in lung cancers predict for sensitivity to EGFR kinase inhibitors. HER2 (also known as NEU, EGFR2, or ERBB2) is a member of the EGFR...
Medaka genome mapping and sequencing : toward complete genome sequence (2004)
Sasaki, T., Asakawa, S., Shimizu, A., Ishikawa, S. K., Imai, S., Himmelbauer, H., ...
Current status of medaka genetics and genomics. The Medaka Genome Initiative (MGI). (2004)
Schartl, M., Nanda, I., Kondo, M., Schmid, M., Asakawa, S., Sasaki, T., ...
Orogenic Lherzolites and Mantle Processes: Editorial (2004)
MENZIES, M., OBATA, M., ARAI, S., KOHLSTEDT, D., FREY, F., ...
Sitharam, Thallak G, Dinesh, SV, Shimizu, N
In this paper, numerical simulation results of isotropic compression and triaxial static shear tests under drained and undrained stress paths on polydisperse assembly of loose and dense spheres are...
Nagano, T., Horino, H., Mitsuno, T., Shimizu, N.
Rosana G. Moreira, Editor-in-Chief; Texas A&M University
Practical equivalent continuum characterization of jointed rock masses (2001)
Sitharam, TG, Sridevi, J, Shimizu, N
A simple practical method to characterize the strength and stiffness of jointed rock masses is presented in this paper. The empirical relations for the strength and stiffness of rock masses have been...
Initial sequencing and analysis of the human genome (2001)
Lander, ES, Linton, LM, Birren, B, Nusbaum, C, Zody, MC, Baldwin, J, ...
The human genome holds an extraordinary trove of information about human development, physiology, medicine and evolution. Here we report the results of an international collaboration to produce and...
CIGR E-Journal Volume 3 (2001)
Munack, A., Nova, A., Pozeliene, A., Sawamura, A., Sumorek, A., Zairi, A., ...
Rosana G. Moreira, Editor-in-Chief; Texas A&M University
Re-Os Isotopes in the Horoman Peridotite: Evidence for Refertilization? (2001)
SAAL, A. E., TAKAZAWA, E., FREY, F. A., SHIMIZU, N., HART, S. R.
Re–Os isotopic data for 20 samples from a well-characterized 140 m section across a layered sequence, ranging from plagioclase lherzolite through lherzolite to harzburgite, of the Horoman...
Orogenic Lherzolites and Mantle Processes: Editorial (2001)
MENZIES, M. A., VANNUCCI, R., BODINIER, J. L., FREY, F. A., SHIMIZU, N., KELEMEN, P. B., ...
Mattielli, N., Weis, D., Scoates, J. S., Shimizu, N., GréGoire, M., ...
A combined petrographic, geochemical and Sr–Nd–Pb isotopic investigation of peridotite xenoliths from the Kerguelen Archipelago (southern Indian Ocean) provides new insights into melt migration...
Keio Mutation Database for eye disease genes (KMeyeDB) (1999)
Minoshima, S, Mitsuyama, S, Ohno, S, Kawamura, T, Shimizu, N
Polybaric Petrogenesis of Mafic Layers in the Horoman Peridotite Complex, Japan (1999)
Takazawa, E., Frey, F. A., Shimizu, N., Saal, A., Obata, M.
Two major types of mafic granulite layers occur within the Horoman peridotite, an 8 km × 10 km × 3 km orogenic lherzolite exposed in the high-T and low-P Hidaka metamorphic belt of Hokkaido, Japan....
Optical conductivity of the Kondo insulator YbB12: Gap formation and low-energy excitations (1998)
Okamura, Hidekazu, Kimura, S., Shinozaki, H., Nanba, Takao, Iga, F., Shimizu, N., ...
One-megabase sequence analysis of the human immunoglobulin lambda gene locus (1997)
Kawasaki, K, Minoshima, S, Nakato, E, Shibuya, K, Shintani, A, Schmeits, JL, ...
The most intense endogenous transforming growth factor (TGF)-&bgr;1 expression was detected on osteoblasts and fibroblasts in the mid-palatal suture 24 hours after the start of palatal expansion with...
The organization of the human immunoglobulin lambda gene locus (1995)
Kawasaki, K, Minoshima, S, Schooler, K, Kudoh, J, Asakawa, S, De Jong, PJ, ...
Metasomatism-induced Melting in Mantle Xenoliths from Mongolia (1994)
IONOV, D. A., HOFMANN, A. W., SHIMIZU, N.
Mantle xenoliths from two locations in Mongolia contain patches of glass-phenocryst aggregates (‘melt pockets’) up to 1 cm in diameter, including one ‘composite’ xenolith, which shows a...
Sugita, S, Shimizu, N, Watanabe, K, Mizukami, M, Morio, T, Sugamoto, Y, ...
Kanno, H, Watabe, D, Shimizu, N, Sawai, T
Chronic active Epstein–Barr virus (EBV) infection (CAEBV) is characterized by chronic recurrent infectious mononucleosis-like symptoms. Approximately one-fourth of CAEBV patients develop vascular...
Fujita, T, Doihara, H, Kawasaki, K, Takabatake, D, Takahashi, H, Washio, K, ...
Trastuzumab is the only HER2/neu-directed therapy to have received Food and Drug Administration approval for the treatment of patients with metastatic breast cancer. The efficacy of trastuzumab...
Zhang, Y, Ohyashiki, J H, Takaku, T, Shimizu, N, Ohyashiki, K
Nasal NK/T-cell lymphoma is an aggressive subtype of non-Hodgkin lymphoma (NHL) that is closely associated with Epstein–Barr virus (EBV). The clonal expansion of EBV-infected NK or T cells is also...
Dote, H, Toyooka, S, Tsukuda, K, Yano, M, Ota, T, Murakami, M, ...
The human DOC-2/DAB2 interactive protein (hDAB2IP) gene is a novel member of the Ras GTPase-activating family and has been demonstrated to be a tumour-suppressor gene inactivated by methylation in...
Sumitomo, M, Tachibana, M, Murai, M, Hayakawa, M, Nakamura, H, Takayanagi, A, ...
We investigated the interaction of endogenous interleukin (IL)-1β, IL-1ra, and interleukin-1β converting enzyme (ICE) in four human urological cancer cell lines, KU-19-19, KU-1, KU-2 and KU-19-20....
Kunisue, H, Kurebayashi, J, Otsuki, T, Tang, C K, Kurosumi, M, Yamamoto, S, ...
Anti-oestrogen is effective for the treatment of oestrogen receptor (ER)-positive breast carcinomas, butmost of these tumours become resistant to anti-oestrogen. It has been suggested that...
Hoshi, M, Otagiri, N, Shiwaku, H O, Asakawa, S, Shimizu, N, Kaneko, Y, ...
Neuroblastoma (NB) is a well-known malignant disease in infants, but its molecular mechanisms have not yet been fully elucidated. To investigate the genetic contribution of abnormalities on the long...
The relationship between aberrant methylation and survival in non-small-cell lung cancers
Toyooka, S, Suzuki, M, Maruyama, R, Toyooka, K O, Tsukuda, K, Fukuyama, Y, ...
Date, H, Kiura, K, Ueoka, H, Tabata, M, Aoe, M, Andou, A, ...
We conducted a phase I/II study to investigate whether the surgical resection after induction chemotherapy with cisplatin and irinotecan was feasible and could improve the treatment outcome for...
Shimizu, N, Nagata, C, Shimizu, H, Kametani, M, Takeyama, N, Ohnuma, T, ...
Katayama, H, Ueoka, H, Kiura, K, Tabata, M, Kozuki, T, Tanimoto, M, ...