N. Van Pelt

Cardioselective nitric oxide synthase 3 gene transfer protects against myocardial ischemia-reperfusion injury in pigs (2003)

Szelid, Z, Sinnaeve, Peter; U0011642, Vermeersch, Pieter; U0035259, Gillijns, H, Pellens, Marijke; U0033117, Van Pelt, N, ...

Residual pulmonary vasoreactivity to inhaled nitric oxide in patients with severe obstructive pulmonary hypertension and Eisenmenger syndrome (2001)

Van Pelt, N, Gillyns, H, Gewillig, M, Janssens, S

OBJECTIVE: To determine whether inhaled NO (iNO) can reduce pulmonary vascular resistance in adults with congenital heart disease and obstructive pulmonary hypertension or Eisenmenger syndrome....

L-arginine administration reduces neointima formation after stent injury in rats by a nitric oxide-mediated mechanism (2001)

Nong, Z, Stabile, E, Varenne, O, Gillijns, H, ...

The clinical outcome of vascular stenting is limited by in-stent stenosis. Increased nitric oxide (NO)/cGMP signaling by L-arginine (L-Arg) supplementation, the substrate for NO synthase (NOS), or...

Overexpression of cytochrome P4502C9, an epoxygenase with hyperpolarizing activity, modulates pulmonary vascular tone in murine lungs (2001)

Vermeersch, Pieter; U0035259, Fisslthaler, B, Busse, R, Pellens, Marijke; U0033117, Van Pelt, N, ...

Overexpression of a constitutively-active, cGMP-independent protein kinase mutant reduces in-stent restenosis in porcine coronary arteries (2001)

Sinnaeve, PR, Chiche, JD, Gillijns, H, Van Pelt, N, Collen, Desire; U0016103, Van De Werf, Frans; U0009589, ...

Overexpression of a mutant, cGMP-independent protein kinase reduces restenosis in stented porcine coronary arteries (2001)

Sinnaeve, Peter; U0011642, Gillijns, H, Van Pelt, N, Chiche, JD, Bloch, K, Collen, Desire; U0016103, ...

Prolonged L-arginine administration but not inducible nitric oxide synthase gene transfer reduces neointima formation after stent injury in rats (2001)

Vermeersch, Pieter; U0035259, Nong, ZX, Gillijns, H, Van Pelt, N, Varenne, O, Stabile, E, ...

Regional myocardial nitric oxide synthase 3 gene transfer reduces tissue-specific consequences of anti adenoviral immune response (2001)

Szelid, Z, Sinnaeve, Peter; U0011642, Gillijns, H, Pellens, Marijke; U0033117, Laurysens, Veerle; U0022303, Van Pelt, N, ...

Soluble guanylate cyclase alpha(1) and beta(1) gene transfer increases NO responsiveness and reduces neointima formation after balloon injury in rats via antiproliferative and antimigratory effects (2001)

Chiche, J D, Nong, Z, Varenne, O, Van Pelt, N, Gillijns, H, ...

In vascular smooth muscle cells, NO stimulates the synthesis of cGMP by soluble guanylate cyclase (sGC), a heterodimer composed of alpha(1) and beta(1) subunits. NO/cGMP signal transduction affects...

Aerosol gene transfer with inducible nitric oxide synthase reduces hypoxic pulmonary hypertension and pulmonary vascular remodeling in rats (2000)

Budts, Werner; U0037749, Nong, ZX, Van Pelt, N, Gillijns, H, Gerard, R, ...

BACKGROUND: Nitric oxide (NO) is a potent vasodilator with an important role in the regulation of pulmonary vascular tone. The effects of NO synthase (NOS) gene transfer on pulmonary vascular...

Nitric oxide inhalation detects residual pulmonary vasoreactivity in patients with severe obstructive pulmonary hypertension and Eisenmenger syndrome (2000)

Budts, Werner; U0037749, Van Pelt, N, Gillyns, H, Van De Werf, Frans; U0009589, Janssens, S

Adenovirus-mediated transfer of soluble guanylayte cyclase alpha 1 and beta 1 subunits increases nitric oxide responsiveness and reduces neointima formation in balloon-injured rat carotid arteries (1998)

Sinnaeve, Peter; U0011642, Chiche, JD, Nong, ZX, Varenne, O, Van Pelt, N, Gerard, RD, ...

Comparison of local delivery catheters for intracoronary gene transfer in pigs (1998)

Varenne, O, Gerard, RD, Sinnaeve, Peter; U0011642, Gillijns, H, Wauterickx, K, Van Pelt, N, ...

Local adenovirus-mediated transfer of human endothelial nitric oxide synthase reduces luminal narrowing after coronary angioplasty in pigs (1998)

Pislaru, S, Van Pelt, N, Gerard, R D, Zoldhelyi, P, ...

BACKGROUND: Nitric oxide, synthesized from L-arginine by nitric oxide synthase (NOS), is a vasodilator and inhibits vascular smooth muscle cell (SMC) proliferation and migration. The effects of local...

Human endothelial nitric oxide synthase gene transfer inhibits vascular smooth muscle cell proliferation and neointima formation after balloon injury in rats (1998)

Flaherty, D, Nong, Z, Varenne, O, Van Pelt, N, ...

BACKGROUND: Loss of endothelial NO production after arterial injury may contribute to restenosis, characterized by neointima formation and elastic recoil. Adenovirus-mediated transfer of the gene...

Nitric oxide inhalation inhibits platelet aggregation and platelet-mediated pulmonary thrombosis in rats (1997)

Van Pelt, N

Endothelium-derived nitric oxide (NO) inhibits in vitro platelet aggregation via a cGMP-dependent mechanism. The effect of inhaled NO on platelet-mediated pulmonary thrombosis following intravenous...

Memo: to scientists and conservationists in the Great Basin re Environmental Impact Statement on the MX missile system (1981)

Van Pelt, N.

Memo: to scientists and conservationists in the Great Basin re Environmental Impact Statement on the MX missile system (1981)

Van Pelt, N.

Residual pulmonary vasoreactivity to inhaled nitric oxide in patients with severe obstructive pulmonary hypertension and Eisenmenger syndrome

Budts, W, Van Pelt, N, Gillyns, H, Gewillig, M, Janssens, S

OBJECTIVE—To determine whether inhaled NO (iNO) can reduce pulmonary vascular resistance in adults with congenital heart disease and obstructive pulmonary hypertension or Eisenmenger...