John Danesh, Stephen Kaptoge, Andrea G. Mann, Nadeem Sarwar, Angela Wood, Sara B. Angleman, ...
BackgroundThe relevance to coronary heart disease (CHD) of cytokines that govern inflammatory cascades, such as interleukin-6 (IL-6), may be underestimated because such mediators are short acting and...
Sagoo, Gurdeep S., Tatt, Iain, Salanti, Georgia, Butterworth, Adam S., Sarwar, Nadeem, Van Maarle, Merel, ...
Lipoprotein lipase (LPL) is a key enzyme in lipoprotein metabolism and a major candidate gene for coronary heart disease (CHD). The authors assessed associations between 7 LPL polymorphisms and lipid...
Sarwar, Nadeem, Sattar, Naveed, Gudnason, Vilmundur, Danesh, John
Aims It is uncertain whether there are associations between circulating levels of insulin markers and coronary heart disease (CHD) risk. We report an updated meta-analysis of studies of circulating...
Danesh, John, Kaptoge, Stephen, Mann, Andrea G, Sarwar, Nadeem, Wood, Angela, Angleman, Sara B, ...
John Danesh and colleagues show that long-term IL-6 levels are associated with coronary heart disease risk, thus highlighting the potential relevance of IL-6−mediated pathways to coronary heart...