Nadia Bucurenci

Genetic and Biochemical Characterization of Salmonella enterica Serovar Typhi Deoxyribokinase

Tourneux, Lise, Bucurenci, Nadia, Saveanu, Cosmin, Kaminski, Pierre Alexandre, Bouzon, Madeleine, Pistotnik, Elisabeth, ...

We identified in the genome of Salmonella enterica serovar Typhi the gene encoding deoxyribokinase, deoK. Two other genes, vicinal to deoK, were determined to encode the putative deoxyribose...

Mutational Analysis of UMP Kinase from Escherichia coli

Bucurenci, Nadia, Serina, Lidia, Zaharia, Cristina, Landais, Stéphanie, Danchin, Antoine, Bârzu, Octavian

UMP kinase from Escherichia coli is one of the four regulatory enzymes involved in the de novo biosynthetic pathway of pyrimidine nucleotides. This homohexamer, with no counterpart in eukarya, might...

Substitution of an Alanine Residue for Glycine 146 in TMP Kinase from Escherichia coli Is Responsible for Bacterial Hypersensitivity to Bromodeoxyuridine

Tourneux, Lise, Bucurenci, Nadia, Lascu, Ioan, Sakamoto, Hiroshi, Briand, Gilbert, Gilles, Anne-Marie

The wild-type TMP kinases from Escherichia coli and from a strain hypersensitive to 5-bromo-2′-deoxyuridine were characterized comparatively. The mutation at codon 146 causes the substitution of an...

Genetic and Biochemical Characterization of Salmonella enterica Serovar Typhi Deoxyribokinase

Tourneux, Lise, Bucurenci, Nadia, Saveanu, Cosmin, Kaminski, Pierre Alexandre, Bouzon, Madeleine, Pistotnik, Elisabeth, ...

We identified in the genome of Salmonella enterica serovar Typhi the gene encoding deoxyribokinase, deoK. Two other genes, vicinal to deoK, were determined to encode the putative deoxyribose...

Mutational Analysis of UMP Kinase from Escherichia coli

Bucurenci, Nadia, Serina, Lidia, Zaharia, Cristina, Landais, Stéphanie, Danchin, Antoine, Bârzu, Octavian

UMP kinase from Escherichia coli is one of the four regulatory enzymes involved in the de novo biosynthetic pathway of pyrimidine nucleotides. This homohexamer, with no counterpart in eukarya, might...

Substitution of an Alanine Residue for Glycine 146 in TMP Kinase from Escherichia coli Is Responsible for Bacterial Hypersensitivity to Bromodeoxyuridine

Tourneux, Lise, Bucurenci, Nadia, Lascu, Ioan, Sakamoto, Hiroshi, Briand, Gilbert, Gilles, Anne-Marie

The wild-type TMP kinases from Escherichia coli and from a strain hypersensitive to 5-bromo-2′-deoxyuridine were characterized comparatively. The mutation at codon 146 causes the substitution of an...