Toyama, Tatsuya, Yamashita, Hiroko, Sugiura, Hiroshi, Kondo, Naoto, Iwase, Hirotaka, Fujii, Yoshitaka
Objective The CYP2D6 enzyme plays a major role in converting tamoxifen to its active metabolites. We investigated whether there is an association between the CYP2D6*10 allele and clinical outcome in...
Toyama, Tatsuya, Yamashita, Hiroko, Kondo, Naoto, Okuda, Katsuhiro, Takahashi, Satoru, Sasaki, Hidefumi, ...
Abstract Background Triple-negative breast cancer (estrogen receptor-, progesterone receptor-, and HER2-negative) (TNBC) is a high risk breast cancer that lacks specific therapy targeting these...
Hamaguchi, Maho, Nishio, Mariko, Toyama, Tatsuya, Sugiura, Hiroshi, Kondo, Naoto, Fujii, Yoshitaka, ...
Objective Genetic polymorphisms associated with breast cancer risk are likely to differ among ethnic and molecular subtypes. The ability to identify genetic polymorphisms affecting the risk of...
Toyama, Tatsuya, Zhang, Zhenhuan, Nishio, Mariko, Hamaguchi, Maho, Kondo, Naoto, Iwase, Hirotaka, ...
Abstract Introduction Single-nucleotide polymorphisms (SNPs) in codon 72 of the TP53 (also known as p53 ) gene (rs1042522) and in the promoter region of the MDM2 gene (SNP309; rs2279744) have been...
Toyama, Tatsuya, Zhang, Zhenhuan, Iwase, Hirotaka, Yamashita, Hiroko, Ando, Yoshiaki, Hamaguchi, Maho, ...
Background: While Snail is a zinc-finger transcription factor that triggers the epithelial-mesenchymal transition, it has also been reported to be indirectly regulated by estrogen receptor α (ERα)...
Toyama, Tatsuya, Zhang, Zhenhuan, Iwase, Hirotaka, Yamashita, Hiroko, Ando, Yoshiaki, Hamaguchi, Maho, ...
Background: While Snail is a zinc-finger transcription factor that triggers the epithelial- mesenchymal transition, it has also been reported to be indirectly regulated by estrogen receptor α (ERα)...