Saha, Indranil, Chatterjee, Bhaswati, Shamala, Narayanaswamy, Balaram, Padmanabhan
Multiple conformational states in heterochiral diproline sequences have been characterized in the solid state by the determination of the crystal structures of seven tripeptides in enantiomeric and...
Vasudev, Prema G, Rai, Rajkishor, Shamala, Narayanaswamy, Balaram, Padmanabhan
The author has brought to our attention the following revision for Table II of the article listed above, published in Biopolymers 2008, 90(2):138–150. See the revised table shown on the following...
Vasudev, Prema G, Rai, Rajkishor, Shamala, Narayanaswamy, Balaram, Padmanabhan
The conformational preferences of the 3,3-disubstituted \beta-amino acid residue, 1-aminocyclohexaneacetic acid $(\beta^{3,3}Ac_6c)$ have been investigated by determining the crystal structures of...
Chatterjee, Bhaswati, Saha, Indranil, Raghothama, Srinivasarao, Aravinda, Subrayashastry, Rai, Rajkishor, Shamala, Narayanaswamy, ...
Diproline segments have been advanced as templates for nucleation of folded structure in designed peptides. The conformational space available to homochiral and heterochiral diproline segments has...
Tryptophan Rich Peptides: Influence of Indole Rings on Backbone Conformation (2007)
Mahalakshmi, Radhakrishnan, Sengupta, Anindita, Raghothama, Srinivasarao, Shamala, Narayanaswamy, Balaram, Padmanabhan
Synthetic peptides with defined secondary structure scaffolds, namely hairpins and helices, containing tryptophan residues, have been investigated in this study to probe the influence of a large...
Rai, Rajkishor, Vasudev, Prema G, Ananda, Kuppanna, Raghothama, Srinivasarao, Shamala, Narayanaswamy, Karle, Isabella L, ...
The \beta turn segment in designed peptide hairpins has been expanded by the insertion of \beta-, \gamma- and \delta amino acids at the i+2 position. The model octapeptides...
Structural studies of model peptides \beta-, \gamma- containing and \delta- amino acids (2006)
Sengupta, Anindita, Aravinda, Subrayashastry, Shamala, Narayanaswamy, Raja, Muruga Poopathi K, Balaram, Padmanabhan
The crystal structures of five model peptides Piv-Pro-Gly-NHMe (1), Piv-Pro-\beta Gly-NHMe (2), Piv-Pro- \beta Gly-OMe (3), Piv-Pro- \delta Ava-OMe (4) and Boc-Pro- \gamma Abu-OH (5) are described...
Vasudev, Prema G, Shamala, Narayanaswamy, Ananda, Kuppanna, Balaram, Padmanabhan
The insertion of additional atoms into \alpha -polypeptide backbones by the introduction of \beta, \gamma, and higher \omega amino acid residues expands the range of polypeptide secondary...
Harini, Veldore Vidya, Aravinda, Subrayashastry, Rai, Rajkishor, Shamala, Narayanaswamy, Balaram, Padmanabhan
Peptide $\beta$-hairpin formation is facilitated by centrally positioned D-Pro-Xxx segments. The synthetic peptides Boc-Leu-Phe-Val-D-Pro-$Ac_6c$-Leu-Phe-Val-OMe (1) and...
Aravinda, Subrayashastry, Harini, Veldore Vidya, Shamala, Narayanaswamy, Das, Chittaranjan, Balaram, Padmanabhan
De noVo designed ‚b-hairpin peptides have generally been recalcitrant to crystallization. The crystal structures of four synthetic peptide ‚b-hairpins, Boc-Leu-Val-Val-DPro-Gly-Leu-Phe-Val-OMe...
Hydrogen-Bond Lengths in Polypeptide Helices: No Evidence for Short Hydrogen Bonds (2004)
Aravinda, Subrayashastry, Datta, Saumen, Shamala, Narayanaswamy, Balaram, Padmanabhan
The $3_1_0$ helix and \alpha helix are closely related secondary structures observed in polypeptides. The $3_1_0$ helix is characterized by successive $4\rightarrow1$ $(C_1_0)$ hydrogen bonds...
Rahaman, Abdur, Srinivasan, Naryanaswamy, Shamala, Narayanaswamy, Shaila, Melkote Subbarao
Phosphoprotein (P) of negative sense RNA viruses functions as a transcriptional transactivator of the viral polymerase (L). We report here the characterization of oligomeric P protein of rinderpest...
Aravinda, Subrayashastry, Shamala, Narayanaswamy, Bandyopadhyay, Abhishek, Balaram, Padmanabhan
The structural characterization in crystals of three designed decapeptides containing a double D-segment at the C-terminus is described. The crystal structures of the peptides Boc-Leu-Aib-Val-Xxx-...
Aravinda, Subrayashastry, Ananda, Kuppanna, Shamala, Narayanaswamy, Balaram, Padmanabhan
The crystal structures of four dipeptides that contain the stereochemically constrained gamma-amino acid residue gabapentin (1-(aminomethyl) cyclohexaneacetic acid Gpn) are described. The molecular...
Aravinda, Subrayashastry, Shamala, Narayanaswamy, Das, Chittaranjan, Sriranjini, Arumugam, Karle, Isabella L, Balaram, Padmanabhan
Aromatic-aromatic interactions between phenylalanine side chains in peptides have been probed by the structure determination in crystals of three peptides: Boc-Val-Ala-Phe-Aib-Val-Ala-Phe-Aib-OMe, I;...
Aravinda, Subrayashastry, Shamala, Narayanaswamy, Bandyopadhyay, Abhishek, Balaram, Padmanabhan
The structural characterization in crystals of three designed decapeptides containing a double D-segment at the C-terminus is described. The crystal structures of the peptides...
A right handed peptide helix containing a central double D-amino acid segment (2002)
Aravinda, Subrayashastry, Shamala, Narayanaswamy, Desiraju, Shrilakshmi, Balaram, Padmanabhan
The crystal structure of the 13 residue peptide Boc-Leu-Aib-Val-Ala-Leu-Aib-Val-DAla-DLeu-Aib-Leu-Aib-Val-OMe reveals a continuous helical conformation providing an unambiguous characterization of...
Aravinda, Subrayashastry, Shamala, Narayanaswamy, Rajkishore, Rai, Gopi, Hosahudya N, Balaram, Padmanabhan
Recent progress in the design of beta-hairpin peptides[1] and beta-sheet models has been based on the ability to nucleate reverse turns of the appropriate stereochemistry. D-Pro-Gly[2] and to a...
Shamala, Narayanaswamy, Nagaraj, Ramakrishnan, Balaram, Padmanabhan
The pentapeptide $Tos-{(Aib)}_5-OMe$ adopts a $3_{10}$ helical conformation in the solid state, with three consecutive Type III \beta-turns stabilised by intramolecular hydrogen bonds.