Narisara Chantratita

Toll-Like Receptor 2 Impairs Host Defense in Gram-Negative Sepsis Caused by Burkholderia pseudomallei (Melioidosis) (2007)

W. Joost Wiersinga, Catharina W. Wieland, Mark C. Dessing, Narisara Chantratita, Allen C. Cheng, Direk Limmathurotsakul, ...

BackgroundToll-like receptors (TLRs) are essential in host defense against pathogens by virtue of their capacity to detect microbes and initiate the immune response. TLR2 is seen as the most...

Recurrent Melioidosis in Patients in Northeast Thailand Is Frequently Due to Reinfection Rather than Relapse

Maharjan, Bina, Chantratita, Narisara, Vesaratchavest, Mongkol, Cheng, Allen, Wuthiekanun, Vanaporn, Chierakul, Wirongrong, ...

Human melioidosis is associated with a high rate of recurrent disease, despite adequate antimicrobial treatment. Here, we define the rate of relapse versus the rate of reinfection in 116 patients...

Recurrent Melioidosis in Patients in Northeast Thailand Is Frequently Due to Reinfection Rather than Relapse

Maharjan, Bina, Chantratita, Narisara, Vesaratchavest, Mongkol, Cheng, Allen, Wuthiekanun, Vanaporn, Chierakul, Wirongrong, ...

Human melioidosis is associated with a high rate of recurrent disease, despite adequate antimicrobial treatment. Here, we define the rate of relapse versus the rate of reinfection in 116 patients...

Accuracy of Enzyme-Linked Immunosorbent Assay Using Crude and Purified Antigens for Serodiagnosis of Melioidosis▿

Chantratita, Narisara, Wuthiekanun, Vanaporn, Thanwisai, Aunchalee, Limmathurotsakul, Direk, Cheng, Allen C., Chierakul, Wirongrong, ...

Five enzyme-linked immunosorbent assays developed to detect antibodies to different Burkholderia pseudomallei antigen preparations were evaluated as diagnostic tests for melioidosis in northeast...

Biological Relevance of Colony Morphology and Phenotypic Switching by Burkholderia pseudomallei▿

Chantratita, Narisara, Wuthiekanun, Vanaporn, Boonbumrung, Khaemaporn, Tiyawisutsri, Rachaneeporn, Vesaratchavest, Mongkol, Limmathurotsakul, Direk, ...

Melioidosis is a notoriously protracted illness and is difficult to cure. We hypothesize that the causative organism, Burkholderia pseudomallei, undergoes a process of adaptation involving altered...

Toll-Like Receptor 2 Impairs Host Defense in Gram-Negative Sepsis Caused by Burkholderia pseudomallei (Melioidosis)

Wiersinga, W. Joost, Wieland, Catharina W, Dessing, Mark C, Chantratita, Narisara, Cheng, Allen C, Limmathurotsakul, Direk, ...

Willem Wiersinga and colleagues find up-regulation of multiple Toll-like receptors (TLRs) in peripheral blood cells of patients with melioidosis. However, only TLR2 had an effect on the immune...

Genetic Diversity and Microevolution of Burkholderia pseudomallei in the Environment

Chantratita, Narisara, Wuthiekanun, Vanaporn, Limmathurotsakul, Direk, Vesaratchavest, Mongkol, Thanwisai, Aunchalee, Amornchai, Premjit, ...

The soil dwelling Gram-negative bacterium Burkholderia pseudomallei is the cause of melioidosis, a serious human infection that occurs in Southeast Asia and northern Australia. The purpose of this...

Simultaneous Infection with More than One Strain of Burkholderia pseudomallei Is Uncommon in Human Melioidosis▿

Limmathurotsakul, Direk, Wuthiekanun, Vanaporn, Chantratita, Narisara, Wongsuvan, Gumphol, Thanwisai, Aunchalee, Biaklang, Mayurachat, ...

A prospective study was performed to determine the rate at which patients with melioidosis are infected with more than one strain of Burkholderia pseudomallei. Genotyping of 2,058 bacterial colonies...

Loop-Mediated Isothermal Amplification Method Targeting the TTS1 Gene Cluster for Detection of Burkholderia pseudomallei and Diagnosis of Melioidosis▿

Chantratita, Narisara, Meumann, Ella, Thanwisai, Aunchalee, Limmathurotsakul, Direk, Wuthiekanun, Vanaporn, Wannapasni, Saran, ...

Melioidosis is a severe infection caused by Burkholderia pseudomallei. The timely implementation of effective antimicrobial treatment requires rapid diagnosis. Loop-mediated isothermal amplification...

Rapid Detection of the Pandemic Methicillin-Resistant Staphylococcus aureus Clone ST 239, a Dominant Strain in Asian Hospitals▿

Feil, Edward J., Nickerson, Emma K., Chantratita, Narisara, Wuthiekanun, Vanaporn, Srisomang, Pramot, Cousins, Richard, ...

We describe and validate a novel PCR assay to detect the pandemic hospital-acquired methicillin-resistant Staphylococcus aureus (HA-MRSA) lineage ST 239. Results based on previously uncharacterized...

A Simple Scoring System to Differentiate between Relapse and Re-Infection in Patients with Recurrent Melioidosis

Limmathurotsakul, Direk, Chaowagul, Wipada, Chantratita, Narisara, Wuthiekanun, Vanaporn, Biaklang, Mayurachat, Tumapa, Sarinna, ...

Melioidosis is a serious infectious disease caused by the Gram-negative bacterium, Burkholderia pseudomallei. This organism is present in the environment in areas where melioidosis is endemic (most...

Prevalence and Sequence Diversity of a Factor Required for Actin-Based Motility in Natural Populations of Burkholderia Species▿ †

Sitthidet, Chayada, Stevens, Joanne M., Chantratita, Narisara, Currie, Bart J., Peacock, Sharon J., Korbsrisate, Sunee, ...

Actin-based motility of the melioidosis pathogen Burkholderia pseudomallei requires BimA. We report a high degree of conservation of bimA in 99 B. pseudomallei isolates from the area of endemicity. A...