Nassim Dali-Youcef

The Pro12Ala PPARgamma2 variant determines metabolism at the gene-environment interface. (2009)

Heikkinen, Sami, Argmann, Carmen, Feige, Jérôme N, Koutnikova, Hana, Champy, Marie-France, Dali-Youcef, Nassim, ...

The metabolic impact of the common peroxisome proliferator-activated receptor gamma isoform 2 (PPARgamma2) variant Pro12Ala in human populations has been widely debated. We demonstrate, using a...

Sirtuins: the 'magnificent seven', function, metabolism and longevity. (2007)

Dali-Youcef, Nassim, Lagouge, Marie, Froelich, Sébastien, Koehl, Christian, Schoonjans, Kristina, Auwerx, Johan

The sirtuin family of histone deacetylases (HDACs) was named after their homology to the Saccharomyces cerevisiae gene silent information regulator 2 (Sir2). In the yeast, Sir2 has been shown to...

Adipose tissue-specific inactivation of the retinoblastoma protein protects against diabesity because of increased energy expenditure. (2007)

Dali-Youcef, Nassim, Mataki, Chikage, Coste, Agnès, Messaddeq, Nadia, Giroud, Sylvain, Blanc, Stéphane, ...

The role of the tumor suppressor retinoblastoma protein (pRb) has been firmly established in the control of cell cycle, apoptosis, and differentiation. Recently, it was demonstrated that lack of pRb...

Overexpression of angiotensin II type I receptor in cardiomyocytes induces cardiac hypertrophy and remodeling

Paradis, Pierre, Dali-Youcef, Nassim, Paradis, François W., Thibault, Gaétan, Nemer, Mona

Angiotensin II (AII) is a major determinant of arterial pressure and volume homeostasis, mainly because of its vascular action via the AII type 1 receptor (AT1R). AII has also been implicated in the...

Overexpression of angiotensin II type I receptor in cardiomyocytes induces cardiac hypertrophy and remodeling

Paradis, Pierre, Dali-Youcef, Nassim, Paradis, François W., Thibault, Gaétan, Nemer, Mona

Angiotensin II (AII) is a major determinant of arterial pressure and volume homeostasis, mainly because of its vascular action via the AII type 1 receptor (AT1R). AII has also been implicated in the...

Adipose tissue-specific inactivation of the retinoblastoma protein protects against diabesity because of increased energy expenditure

Dali-Youcef, Nassim, Mataki, Chikage, Coste, Agnès, Messaddeq, Nadia, Giroud, Sylvain, Blanc, Stéphane, ...

The role of the tumor suppressor retinoblastoma protein (pRb) has been firmly established in the control of cell cycle, apoptosis, and differentiation. Recently, it was demonstrated that lack of pRb...