Natalia J. Martinez

A C. elegans genome-scale microRNA network contains composite feedback motifs with high flux capacity (2008)

Martinez, Natalia J., Ow, Maria C., Barrasa, M. Inmaculada, Hammell, Molly, Sequerra, Reynaldo, Doucette-Stamm, Lynn, ...

MicroRNAs (miRNAs) and transcription factors (TFs) are primary metazoan gene regulators. Whereas much attention has focused on finding the targets of both miRNAs and TFs, the transcriptional networks...

The FLYWCH transcription factors FLH-1, FLH-2, and FLH-3 repress embryonic expression of microRNA genes in C. elegans (2008)

Ow, Maria C., Martinez, Natalia J., Olsen, Philip H., Silverman, Howard S., Barrasa, M. Inmaculada, Conradt, Barbara, ...

MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression post-transcriptionally via antisense base-pairing. Although miRNAs are involved in a variety of important biological...

The FLYWCH transcription factors FLH-1, FLH-2, and FLH-3 repress embryonic expression of microRNA genes in C. elegans (2008)

Ow, Maria C., Martinez, Natalia J., Olsen, Philip H., Silverman, Howard S., Barrasa, M. Inmaculada, Conradt, Barbara, ...

MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression post-transcriptionally via antisense base-pairing. Although miRNAs are involved in a variety of important biological...

A C. elegans genome-scale microRNA network contains composite feedback motifs with high flux capacity (2008)

Martinez, Natalia J., Ow, Maria C., Barrasa, M. Inmaculada, Hammell, Molly, Sequerra, Reynaldo, Doucette-Stamm, Lynn, ...

MicroRNAs (miRNAs) and transcription factors (TFs) are primary metazoan gene regulators. Whereas much attention has focused on finding the targets of both miRNAs and TFs, the transcriptional networks...

Genome-scale spatiotemporal analysis of Caenorhabditis elegans microRNA promoter activity (2008)

Martinez, Natalia J., Ow, Maria C., Reece-Hoyes, John S., Barrasa, M. Inmaculada, Ambros, Victor R., Walhout, Albertha J.M.

The Caenorhabditis elegans genome encodes more than 100 microRNAs (miRNAs). Genetic analyses of miRNA deletion mutants have only provided limited insights into miRNA function. To gain insight into...

Matrix and Steiner-triple-system smart pooling assays for high-performance transcription regulatory network mapping (2007)

Vermeirssen, Vanessa, Deplancke, Bart, Barrasa, M. Inmaculada, Reece-Hoyes, John S., Arda, H. Efsun, Grove, Christian A., ...

Yeast one-hybrid (Y1H) assays provide a gene-centered method for the identification of interactions between gene promoters and regulatory transcription factors (TFs). To date, Y1H assays have...

Matrix and Steiner-triple-system smart pooling assays for high-performance transcription regulatory network mapping (2007)

Vermeirssen, Vanessa, Deplancke, Bart, Barrasa, M. Inmaculada, Reece-Hoyes, John S., Arda, H. Efsun, Grove, Christian A., ...

Yeast one-hybrid (Y1H) assays provide a gene-centered method for the identification of interactions between gene promoters and regulatory transcription factors (TFs). To date, Y1H assays have...

A gene-centered C. elegans protein-DNA interaction network (2006)

Deplancke, Bart, Mukhopadhyay, Arnab, Ao, Wanyuan, Elewa, Ahmed M., Grove, Christian A., Martinez, Natalia J., ...

Transcription regulatory networks consist of physical and functional interactions between transcription factors (TFs) and their target genes. The systematic mapping of TF-target gene interactions has...

A protein sensor for siRNA asymmetry (2004)

Tomari, Yukihide, Matranga, Christian B., Haley, Benjamin, Martinez, Natalia J., Zamore, Phillip D.

To act as guides in the RNA interference (RNAi) pathway, small interfering RNAs (siRNAs) must be unwound into their component strands, then assembled with proteins to form the RNA-induced silencing...

Identification of genes that synergize with Cbfb-MYH11 in the pathogenesis of acute myeloid leukemia (2004)

Castilla, Lucio H., Perrat, Paola N., Martinez, Natalia J., Landrette, Sean F., Keys, R., Oikemus, Sarah R., ...

Acute myeloid leukemia subtype M4 with eosinophilia is associated with a chromosome 16 inversion that creates a fusion gene CBFB-MYH11. We have previously shown that CBFB-MYH11 is necessary but not...

A C. elegans genome-scale microRNA network contains composite feedback motifs with high flux capacity

Martinez, Natalia J., Ow, Maria C., Barrasa, M. Inmaculada, Hammell, Molly, Sequerra, Reynaldo, Doucette-Stamm, Lynn, ...

MicroRNAs (miRNAs) and transcription factors (TFs) are primary metazoan gene regulators. Whereas much attention has focused on finding the targets of both miRNAs and TFs, the transcriptional networks...

The FLYWCH transcription factors FLH-1, FLH-2, and FLH-3 repress embryonic expression of microRNA genes in C. elegans

Ow, Maria C., Martinez, Natalia J., Olsen, Philip H., Silverman, Howard S., Barrasa, M. Inmaculada, Conradt, Barbara, ...

MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression post-transcriptionally via antisense base-pairing. Although miRNAs are involved in a variety of important biological...

Genome-scale spatiotemporal analysis of Caenorhabditis elegans microRNA promoter activity

Martinez, Natalia J., Ow, Maria C., Reece-Hoyes, John S., Barrasa, M. Inmaculada, Ambros, Victor R., Walhout, Albertha J.M.

The Caenorhabditis elegans genome encodes more than 100 microRNAs (miRNAs). Genetic analyses of miRNA deletion mutants have only provided limited insights into miRNA function. To gain insight into...