Natalie Roy

Two 5q13 simple tandem repeat loci are in linkage disequilibrium with Type 1 spinal muscular atrophy (1994)

D.McLean, Michael, Roy, Natalie, E.MacKenzle, Alexander, Salih, Maysoon, H.M.Burghes, Arthur, Simard, Louise, ...

The gene for the common recessive neuromuscular disorder spinal muscular atrophy (SMA) has been previously mapped to chromosom0e 5q. We report here linkage disequilibrium analyses of two polymorphic...

A phenotype-sensitizing Apoe-deficient genetic background reveals novel atherosclerosis predisposition loci in the mouse.

Dansky, Hayes M, Shu, Pei, Donavan, M, Montagno, Jill, Nagle, Deborah L, Smutko, John S, ...

Therapeutic intervention for atherosclerosis has predominantly concentrated on regulating cholesterol levels; however, these therapeutics are not efficacious for all patients, suggesting that other...

A phenotype-sensitizing Apoe-deficient genetic background reveals novel atherosclerosis predisposition loci in the mouse.

Dansky, Hayes M, Shu, Pei, Donavan, M, Montagno, Jill, Nagle, Deborah L, Smutko, John S, ...

Therapeutic intervention for atherosclerosis has predominantly concentrated on regulating cholesterol levels; however, these therapeutics are not efficacious for all patients, suggesting that other...

MLN8054, a Small-Molecule Inhibitor of Aurora A, Causes Spindle Pole and Chromosome Congression Defects Leading to Aneuploidy▿ †

Hoar, Kara, Chakravarty, Arijit, Rabino, Claudia, Wysong, Deborah, Bowman, Douglas, Roy, Natalie, ...

Aurora A kinase plays an essential role in the proper assembly and function of the mitotic spindle, as its perturbation causes defects in centrosome separation, spindle pole organization, and...