Nathalie Daigle

1 (2008)

Nathalie Daigle, Joël Beaudouin, Gabriela Imreh, Einar Hallberg

Nuclear pore complexes form immobile networks and have a very low turnover in live mammalian cells

Automatic Identification of Subcellular Phenotypes on Human Cell Arrays (2004)

Conrad, Christian, Erfle, Holger, Warnat, Patrick, Daigle, Nathalie, Lörch, Thomas, Ellenberg, Jan, ...

Light microscopic analysis of cell morphology provides a high-content readout of cell function and protein localization. Cell arrays and microwell transfection assays on cultured cells have made cell...

A predictable ligand regulated expression strategy for stably integrated transgenes in mammalian cells in culture (2002)

Anastassiadis,Konstantinos, Kim,Jin-Hyun, Daigle,Nathalie, Sprengel,Rolf, Schöler,Hans R., Stewart,A. Francis

Several strategies for regulated stable transgene expression in mammalian cells have been described. These strategies have different strengths and weaknesses, however they all share a common problem,...

A predictable ligand regulated expression strategy for stably integrated transgenes in mammalian cells in culture (2002)

Anastassiadis, Konstantinos, Kim, Jin-Hyun, Daigle, Nathalie, Sprengel, Rolf, Schöler, Hans R., Stewart, A. Francis

Several strategies for regulated stable transgene expression in mammalian cells have been described. These strategies have different strengths and weaknesses, however they all share a common problem,...

Hepatocyte Nuclear Factor 3β (Foxa2) Is Dispensable for Maintaining the Differentiated State of the Adult Hepatocyte

Sund, Newman J., Ang, Siew-Lan, Sackett, Sara Dutton, Shen, Wei, Daigle, Nathalie, Magnuson, Mark A., ...

Liver-specific gene expression is controlled by a heterogeneous group of hepatocyte-enriched transcription factors. One of these, the winged helix transcription factor hepatocyte nuclear factor 3β...

Automatic Identification of Subcellular Phenotypes on Human Cell Arrays

Conrad, Christian, Erfle, Holger, Warnat, Patrick, Daigle, Nathalie, Lörch, Thomas, Ellenberg, Jan, ...

Light microscopic analysis of cell morphology provides a high-content readout of cell function and protein localization. Cell arrays and microwell transfection assays on cultured cells have made cell...

Hepatocyte Nuclear Factor 3β (Foxa2) Is Dispensable for Maintaining the Differentiated State of the Adult Hepatocyte

Sund, Newman J., Ang, Siew-Lan, Sackett, Sara Dutton, Shen, Wei, Daigle, Nathalie, Magnuson, Mark A., ...

Liver-specific gene expression is controlled by a heterogeneous group of hepatocyte-enriched transcription factors. One of these, the winged helix transcription factor hepatocyte nuclear factor 3β...

Automatic Identification of Subcellular Phenotypes on Human Cell Arrays

Conrad, Christian, Erfle, Holger, Warnat, Patrick, Daigle, Nathalie, Lörch, Thomas, Ellenberg, Jan, ...

Light microscopic analysis of cell morphology provides a high-content readout of cell function and protein localization. Cell arrays and microwell transfection assays on cultured cells have made cell...

Dissecting the Contribution of Diffusion and Interactions to the Mobility of Nuclear Proteins

Beaudouin, Joël, Mora-Bermúdez, Felipe, Klee, Thorsten, Daigle, Nathalie, Ellenberg, Jan

Quantitative characterization of protein interactions under physiological conditions is vital for systems biology. Fluorescence photobleaching/activation experiments of GFP-tagged proteins are...

Quantitative kinetic analysis of nucleolar breakdown and reassembly during mitosis in live human cells

Leung, Anthony Kar Lun, Gerlich, Daniel, Miller, Gail, Lyon, Carol, Lam, Yun Wah, Lleres, David, ...

One of the great mysteries of the nucleolus surrounds its disappearance during mitosis and subsequent reassembly at late mitosis. Here, the relative dynamics of nucleolar disassembly and reformation...

An evolutionarily conserved NPC subcomplex, which redistributes in part to kinetochores in mammalian cells

Belgareh, Naïma, Rabut, Gwénaël, Baï, Siau Wei, Van Overbeek, Megan, Beaudouin, Joël, Daigle, Nathalie, ...

The nuclear pore complexes (NPCs) are evolutionarily conserved assemblies that allow traffic between the cytoplasm and the nucleus. In this study, we have identified and characterized a novel human...

Nuclear envelope breakdown in starfish oocytes proceeds by partial NPC disassembly followed by a rapidly spreading fenestration of nuclear membranes

Lénárt, Péter, Rabut, Gwénaël, Daigle, Nathalie, Hand, Arthur R., Terasaki, Mark, Ellenberg, Jan

Breakdown of the nuclear envelope (NE) was analyzed in live starfish oocytes using a size series of fluorescently labeled dextrans, membrane dyes, and GFP-tagged proteins of the nuclear pore complex...

Simple epithelium keratins 8 and 18 provide resistance to Fas-mediated apoptosis. The protection occurs through a receptor-targeting modulation

Gilbert, Stéphane, Loranger, Anne, Daigle, Nathalie, Marceau, Normand

Keratins 8 and 18 belong to the keratin family of intermediate filament (IF) proteins and constitute a hallmark for all simple epithelia, including the liver. Hepatocyte IFs are made solely of...

Nuclear pore complexes form immobile networks and have a very low turnover in live mammalian cells

Daigle, Nathalie, Beaudouin, Joël, Hartnell, Lisa, Imreh, Gabriela, Hallberg, Einar, Lippincott-Schwartz, Jennifer, ...

The nuclear pore complex (NPC) and its relationship to the nuclear envelope (NE) was characterized in living cells using POM121–green fluorescent protein (GFP) and GFP-Nup153, and GFP–lamin B1....