Arhel, Nathalie J, Souquere-Besse, Sylvie, Charneau, Pierre
Abstract HIV-1 and other lentiviruses have the unique ability among retroviruses to efficiently replicate in non-dividing cells as a result of the active nuclear import of their DNA genome across an...
Arhel, Nathalie J., Packham, Graham, Townsend, Paul A., Collard, Tracey J., H-Zadeh, Akram M., Sharp, Adam, ...
Although the retinoblastoma susceptibility gene RB1 is inactivated in a wide range of human tumours, overexpression in colonic carcinomas has been linked to the antiapoptotic function of the protein....
Arhel, Nathalie J., Packham, Graham, Townsend, Paul A., Collard, Tracey J., H-Zadeh, Akram M., Sharp, Adam, ...
Although the retinoblastoma susceptibility gene RB1 is inactivated in a wide range of human tumours, overexpression in colonic carcinomas has been linked to the antiapoptotic function of the protein....
Arhel, Nathalie J, Souquere-Besse, Sylvie, Charneau, Pierre
HIV-1 and other lentiviruses have the unique ability among retroviruses to efficiently replicate in non-dividing cells as a result of the active nuclear import of their DNA genome across an...
Arhel, Nathalie J, Souquere-Besse, Sylvie, Charneau, Pierre
HIV-1 and other lentiviruses have the unique ability among retroviruses to efficiently replicate in non-dividing cells as a result of the active nuclear import of their DNA genome across an...
HIV-1 DNA Flap formation promotes uncoating of the pre-integration complex at the nuclear pore
Arhel, Nathalie J, Souquere-Besse, Sylvie, Munier, Sandie, Souque, Philippe, Guadagnini, Stéphanie, Rutherford, Sandra, ...
The HIV-1 central DNA Flap acts as a cis-acting determinant of HIV-1 genome nuclear import. Indeed, DNA-Flap re-insertion within lentiviral-derived gene transfer vectors strongly stimulates gene...