Cellitti, Jason, Llinas, Manuel, Echols, Nathaniel, Shank, Elizabeth A., Gillespie, Blake, Kwon, Ester, ...
Small proteins are generally observed to fold in an apparent two-state manner. Recently, however, more sensitive techniques have demonstrated that even seemingly single-domain proteins are actually...
The Database of Macromolecular Motions: new features added at the decade mark (2006)
Flores, Samuel, Echols, Nathaniel, Milburn, Duncan, Hespenheide, Brandon, Keating, Kevin, Lu, Jason, ...
The database of molecular motions, MolMovDB (http://molmovdb.org), has been in existence for the past decade. It classifies macromolecular motions and provides tools to interpolate between two...
Alexandrov, Vadim, Lehnert, Ursula, Echols, Nathaniel, Milburn, Duncan, Engelman, Donald, Gerstein, Mark
We carry out an extensive statistical study of the applicability of normal modes to the prediction of mobile regions in proteins. In particular, we assess the degree to which the observed motions...
Chern-sing Goh, Ning Lan, Nathaniel Echols, Shawn M. Douglas, Duncan Milburn, Paul Bertone, ...
We present version 2 of the SPINE system for structural proteomics. SPINE is available over the web at
ExpressYourself: a modular platform for processing and visualizing microarray data (2003)
Luscombe, Nicholas M., Royce, Thomas E., Bertone, Paul, Echols, Nathaniel, Horak, Christine E., Chang, Joseph T., ...
DNA microarrays are widely used in biological research; by analyzing differential hybridization on a single microarray slide, one can detect changes in mRNA expression levels, increases in DNA copy...
Goh, Chern-Sing, Lan, Ning, Echols, Nathaniel, Douglas, Shawn M., Milburn, Duncan, Bertone, Paul, ...
We present version 2 of the SPINE system for structural proteomics. SPINE is available over the web at http://nesg.org. It serves as the central hub for the Northeast Structural Genomics Consortium,...
MolMovDB: analysis and visualization of conformational change and structural flexibility (2003)
Echols, Nathaniel, Milburn, Duncan, Gerstein, Mark
The Database of Macromolecular Movements (http://MolMovDB.org) is a collection of data and software pertaining to flexibility in protein and RNA structures. The database is organized into two parts....
Echols, Nathaniel, Harrison, Paul, Balasubramanian, Suganthi, Luscombe, Nicholas M., Bertone, Paul, Zhang, Zhaolei, ...
Based on searches for disabled homologs to known proteins, we have identified a large population of pseudogenes in four sequenced eukaryotic genomes—the worm, yeast, fly and human (chromosomes 21...
Harrison, Paul M., Hegyi, Hedi, Balasubramanian, Suganthi, Luscombe, Nicholas M., Bertone, Paul, Echols, Nathaniel, ...
Harrison, Paul M., Echols, Nathaniel, Gerstein, Mark B.
Pseudogenes are non-functioning copies of genes in genomic DNA, which may either result from reverse transcription from an mRNA transcript (processed pseudogenes) or from gene duplication and...
Qian, Jiang, Stenger, Brad, Wilson, Cyrus A., Lin, Jimmy, Jansen, Ronald, Teichmann, Sarah A., ...
As the number of protein folds is quite limited, a mode of analysis that will be increasingly common in the future, especially with the advent of structural genomics, is to survey and re-survey the...
Submitted to Nucleic Acids Research (2000)
Paul M. Harrison, Nathaniel Echols, Mark B. Gerstein
2 Pseudogenes are non-functioning copies of genes in genomic DNA, which may either result from reverse transcription from a messenger RNA transcript (termed processed pseudogenes) or from gene...
Harrison, Paul M., Echols, Nathaniel, Gerstein, Mark B.
Pseudogenes are non-functioning copies of genes in genomic DNA, which may either result from reverse transcription from an mRNA transcript (processed pseudogenes) or from gene duplication and...
Qian, Jiang, Stenger, Brad, Wilson, Cyrus A., Lin, Jimmy, Jansen, Ronald, Teichmann, Sarah A., ...
As the number of protein folds is quite limited, a mode of analysis that will be increasingly common in the future, especially with the advent of structural genomics, is to survey and re-survey the...
Echols, Nathaniel, Harrison, Paul, Balasubramanian, Suganthi, Luscombe, Nicholas M., Bertone, Paul, Zhang, Zhaolei, ...
Based on searches for disabled homologs to known proteins, we have identified a large population of pseudogenes in four sequenced eukaryotic genomes—the worm, yeast, fly and human (chromosomes 21...
SPINE 2: a system for collaborative structural proteomics within a federated database framework
Goh, Chern-Sing, Lan, Ning, Echols, Nathaniel, Douglas, Shawn M., Milburn, Duncan, Bertone, Paul, ...
We present version 2 of the SPINE system for structural proteomics. SPINE is available over the web at http://nesg.org. It serves as the central hub for the Northeast Structural Genomics Consortium,...
MolMovDB: analysis and visualization of conformational change and structural flexibility
Echols, Nathaniel, Milburn, Duncan, Gerstein, Mark
The Database of Macromolecular Movements (http://MolMovDB.org) is a collection of data and software pertaining to flexibility in protein and RNA structures. The database is organized into two parts....
ExpressYourself: a modular platform for processing and visualizing microarray data
Luscombe, Nicholas M., Royce, Thomas E., Bertone, Paul, Echols, Nathaniel, Horak, Christine E., Chang, Joseph T., ...
DNA microarrays are widely used in biological research; by analyzing differential hybridization on a single microarray slide, one can detect changes in mRNA expression levels, increases in DNA copy...
The Database of Macromolecular Motions: new features added at the decade mark
Flores, Samuel, Echols, Nathaniel, Milburn, Duncan, Hespenheide, Brandon, Keating, Kevin, Lu, Jason, ...
The database of molecular motions, MolMovDB (), has been in existence for the past decade. It classifies macromolecular motions and provides tools to interpolate between two conformations (the Morph...
Harrison, Paul M., Hegyi, Hedi, Balasubramanian, Suganthi, Luscombe, Nicholas M., Bertone, Paul, Echols, Nathaniel, ...
We have developed an initial approach for annotating and surveying pseudogenes in the human genome. We search human genomic DNA for regions that are similar to known protein sequences and contain...
Harrison, Paul M., Echols, Nathaniel, Gerstein, Mark B.
Pseudogenes are non-functioning copies of genes in genomic DNA, which may either result from reverse transcription from an mRNA transcript (processed pseudogenes) or from gene duplication and...
Qian, Jiang, Stenger, Brad, Wilson, Cyrus A., Lin, Jimmy, Jansen, Ronald, Teichmann, Sarah A., ...
As the number of protein folds is quite limited, a mode of analysis that will be increasingly common in the future, especially with the advent of structural genomics, is to survey and re-survey the...
Echols, Nathaniel, Harrison, Paul, Balasubramanian, Suganthi, Luscombe, Nicholas M., Bertone, Paul, Zhang, Zhaolei, ...
Based on searches for disabled homologs to known proteins, we have identified a large population of pseudogenes in four sequenced eukaryotic genomes—the worm, yeast, fly and human (chromosomes 21...
Harrison, Paul M., Hegyi, Hedi, Balasubramanian, Suganthi, Luscombe, Nicholas M., Bertone, Paul, Echols, Nathaniel, ...
We have developed an initial approach for annotating and surveying pseudogenes in the human genome. We search human genomic DNA for regions that are similar to known protein sequences and contain...
SPINE 2: a system for collaborative structural proteomics within a federated database framework
Goh, Chern-Sing, Lan, Ning, Echols, Nathaniel, Douglas, Shawn M., Milburn, Duncan, Bertone, Paul, ...
We present version 2 of the SPINE system for structural proteomics. SPINE is available over the web at http://nesg.org. It serves as the central hub for the Northeast Structural Genomics Consortium,...
MolMovDB: analysis and visualization of conformational change and structural flexibility
Echols, Nathaniel, Milburn, Duncan, Gerstein, Mark
The Database of Macromolecular Movements (http://MolMovDB.org) is a collection of data and software pertaining to flexibility in protein and RNA structures. The database is organized into two parts....
ExpressYourself: a modular platform for processing and visualizing microarray data
Luscombe, Nicholas M., Royce, Thomas E., Bertone, Paul, Echols, Nathaniel, Horak, Christine E., Chang, Joseph T., ...
DNA microarrays are widely used in biological research; by analyzing differential hybridization on a single microarray slide, one can detect changes in mRNA expression levels, increases in DNA copy...
The Database of Macromolecular Motions: new features added at the decade mark
Flores, Samuel, Echols, Nathaniel, Milburn, Duncan, Hespenheide, Brandon, Keating, Kevin, Lu, Jason, ...
The database of molecular motions, MolMovDB (), has been in existence for the past decade. It classifies macromolecular motions and provides tools to interpolate between two conformations (the Morph...
Fraser, James S, Merlie, John P, Echols, Nathaniel, Weisfield, Shellie R, Mignot, Tâm, Wemmer, David E, ...
The Myxococcus xanthus FrzS protein transits from pole-to-pole within the cell, accumulating at the pole that defines the direction of movement in social (S) motility. Here we show using...
Alexandrov, Vadim, Lehnert, Ursula, Echols, Nathaniel, Milburn, Duncan, Engelman, Donald, Gerstein, Mark
We carry out an extensive statistical study of the applicability of normal modes to the prediction of mobile regions in proteins. In particular, we assess the degree to which the observed motions...
Cellitti, Jason, Llinas, Manuel, Echols, Nathaniel, Shank, Elizabeth A., Gillespie, Blake, Kwon, Ester, ...
Small proteins are generally observed to fold in an apparent two-state manner. Recently, however, more sensitive techniques have demonstrated that even seemingly single-domain proteins are actually...