Scientific Commons: Nechama I. Smorodinsky

Impaired genomic stability and increased oxidative stress exacerbate different features of Ataxia-telangiectasia (2005)

Ziv, Shelly, Brenner, Ori, Amariglio, Ninette, Smorodinsky, Nechama I., Galron, Ronit, Carrion, Danaise V., ...

Ataxia–telangiectasia (A-T) is a multisystem, cancer-predisposing genetic disorder caused by deficiency of the ATM protein. To dissect the A-T phenotype, we augmented specific features of the human...

Impaired genomic stability and increased oxidative stress exacerbate different features of A-T (2005)

Ziv, Shelly, Brenner, Ori, Amariglio, Ninette, Smorodinsky, Nechama I., Galron, Ronit, Carrion, Danaise V, ...

Ataxia-telangiectasia (A-T) is a multisystem, cancer-predisposing genetic disorder caused by deficiency of the ATM protein. In order to dissect the A-T phenotype, we augmented specific features of...

Transmembrane and truncated (SEC) isoforms of MUC1 in the human endometrium and Fallopian tube (2003)

Hey, Neil A, Meseguer, Marcos, Simón, Carlos, Smorodinsky, Nechama I, Wreschner, Daniel H, Ortíz, María, ...

Abstract The cell surface mucin MUC1 is expressed by endometrial epithelial cells with increased abundance in the secretory phase of the menstrual cycle, when it is found both at the apical cell...

Atm Knock-in Mice Harboring an In-frame Deletion Corresponding to the Human ATM 7636del9 Common Mutation Exhibit a Variant Phenotype (2001)

Kevin Spring, Simone Cross, Chung Li, Dianne Watters, Liat Ben-Senior, Paul Waring, ...

This was the first description of a "knock-in" Atm mutant mouse. While it had overlap with Atm "knockout" mice in its phenotype it had a distinct tumorigenic phenotype and has proved a very useful...

Human Cytomegalovirus Protein US2 Interferes with the Expression of Human HFE, a Nonclassical Class I Major Histocompatibility Complex Molecule That Regulates Iron Homeostasis

Ben-Arieh, Sayeh Vahdati, Zimerman, Baruch, Smorodinsky, Nechama I., Yaacubovicz, Margalit, Schechter, Chana, Bacik, Igor, ...

HFE is a nonclassical class I major histocompatibility complex (MHC) molecule that is mutated in the autosomal recessive iron overload disease hereditary hemochromatosis. There is evidence linking...

Transmembrane and truncated (SEC) isoforms of MUC1 in the human endometrium and Fallopian tube

Hey, Neil A, Meseguer, Marcos, Simón, Carlos, Smorodinsky, Nechama I, Wreschner, Daniel H, Ortíz, María Elena, ...

The cell surface mucin MUC1 is expressed by endometrial epithelial cells with increased abundance in the secretory phase of the menstrual cycle, when it is found both at the apical cell surface and...