Neil Hall

A Plasmodium Whole-Genome Synteny Map: Indels and Synteny Breakpoints as Foci for Species-Specific Genes (2005)

Jane M. Carlton, Shelby L. Bidwell, Neil Hall, Jai Ramesar, Chris J. Janse, ...

Whole-genome comparisons are highly informative regarding genome evolution and can reveal the conservation of genome organization and gene content, gene regulatory elements, and presence of...

Plasmodium falciparum Variant Surface Antigen Expression Patterns during Malaria (2005)

Peter C. Bull, Matthew Berriman, Sue Kyes, Michael A. Quail, Neil Hall, Moses M. Kortok, ...

The variant surface antigens expressed on Plasmodium falciparum–infected erythrocytes are potentially important targets of immunity to malaria and are encoded, at least in part, by a family of var...

Pilot survey of expressed sequence tags (ESTs) from the asexual blood stages of Plasmodium vivaxin human patients (2003)

Merino, Emilio F, Fernandez-Becerra, Carmen, Madeira, Alda MBN, Machado, Ariane L, Durham, Alan, Gruber, Arthur, ...

Abstract Background Plasmodium vivax is the most widely distributed human malaria, responsible for 70–80 million clinical cases each year and large socio-economical burdens for countries such as...

The DNA sequence of chromosome I of an African trypanosome: gene content, chromosome organisation, recombination and polymorphism (2003)

Hall, Neil, Berriman, Matthew, Lennard, Nicola J., Harris, Barbara R., Hertz-Fowler, Christiane, Bart-Delabesse, Emmanuelle N., ...

The African trypanosome, Trypanosoma brucei, causes sleeping sickness in humans in sub-Saharan Africa. Here we report the sequence and analysis of the 1.1 Mb chromosome I, which encodes approximately...

Abundant larval transcript-1 and -2 genes from Brugia malayi : diversity of genomic environments but conservation of 5ı promoter sequences functional in Caenorhabditis elegansı (2002)

Gomez-Escobar, Natalia, Gregory, William F, Britton, Collette, Murray, Linda, Corton, Craig, Hall, Neil, ...

The genomic organisation of two abundant larval transcript (alt) genes from the filarial nematode Brugia malayi has been defined. The products of these genes are 78% identical in amino acid sequence,...

Abundant larval transcript-1 and -2 genes from Brugia malayi : diversity of genomic environments but conservation of 5ı promoter sequences functional in Caenorhabditis elegansı (2002)

Gomez-Escobar, Natalia, Gregory, William F, Britton, Collette, Murray, Linda, Corton, Craig, Hall, Neil, ...

The genomic organisation of two abundant larval transcript (alt) genes from the filarial nematode Brugia malayi has been defined. The products of these genes are 78% identical in amino acid sequence,...

A New, Expressed Multigene Family Containing a Hot Spot for Insertion of Retroelements Is Associated with Polymorphic Subtelomeric Regions of Trypanosoma brucei

Bringaud, Frédéric, Biteau, Nicolas, Melville, Sara E., Hez, Stéphanie, El-Sayed, Najib M., Leech, Vanessa, ...

We describe a novel gene family that forms clusters in subtelomeric regions of Trypanosoma brucei chromosomes and partially accounts for the observed clustering of retrotransposons. The ingi and...

The Intestinal Protozoan Parasite Entamoeba histolytica Contains 20 Cysteine Protease Genes, of Which Only a Small Subset Is Expressed during In Vitro Cultivation

Bruchhaus, Iris, Loftus, Brendan J., Hall, Neil, Tannich, Egbert

Cysteine proteases are known to be important pathogenicity factors of the protozoan parasite Entamoeba histolytica. So far, a total of eight genes coding for cysteine proteases have been identified...

The DNA sequence of chromosome I of an African trypanosome: gene content, chromosome organisation, recombination and polymorphism

Hall, Neil, Berriman, Matthew, Lennard, Nicola J., Harris, Barbara R., Hertz-Fowler, Christiane, Bart-Delabesse, Emmanuelle N., ...

The African trypanosome, Trypanosoma brucei, causes sleeping sickness in humans in sub-Saharan Africa. Here we report the sequence and analysis of the 1.1 Mb chromosome I, which encodes approximately...

GeneDB: a resource for prokaryotic and eukaryotic organisms

Hertz-Fowler, Christiane, Peacock, Chris S., Wood, Valerie, Aslett, Martin, Kerhornou, Arnaud, Mooney, Paul, ...

GeneDB (http://www.genedb.org/) is a genome database for prokaryotic and eukaryotic organisms. The resource provides a portal through which data generated by the Pathogen Sequencing Unit at the...

Comparative Genomics of Transcriptional Control in the Human Malaria Parasite Plasmodium falciparum

Coulson, Richard M.R., Hall, Neil, Ouzounis, Christos A.

The life cycle of the parasite Plasmodium falciparum, responsible for the most deadly form of human malaria, requires specialized protein expression for survival in the mammalian host and insect...

An ancestral oomycete locus contains late blight avirulence gene Avr3a, encoding a protein that is recognized in the host cytoplasm

Armstrong, Miles R., Whisson, Stephen C., Pritchard, Leighton, Bos, Jorunn I. B., Venter, Eduard, Avrova, Anna O., ...

The oomycete Phytophthora infestans causes late blight, the potato disease that precipitated the Irish famines in 1846 and 1847. It represents a reemerging threat to potato production and is one of...

Plasmodium falciparum Variant Surface Antigen Expression Patterns during Malaria

Bull, Peter C, Berriman, Matthew, Kyes, Sue, Quail, Michael A, Hall, Neil, Kortok, Moses M, ...

The variant surface antigens expressed on Plasmodium falciparum–infected erythrocytes are potentially important targets of immunity to malaria and are encoded, at least in part, by a family of var...

The genetic map and comparative analysis with the physical map of Trypanosoma brucei

MacLeod, Annette, Tweedie, Alison, McLellan, Sarah, Taylor, Sonya, Hall, Neil, Berriman, Matthew, ...

Trypanosoma brucei is the causative agent of African sleeping sickness in humans and contributes to the debilitating disease ‘Nagana’ in cattle. To date we know little about the genes that...

A Plasmodium Whole-Genome Synteny Map: Indels and Synteny Breakpoints as Foci for Species-Specific Genes

Kooij, Taco W. A, Carlton, Jane M, Bidwell, Shelby L, Hall, Neil, Ramesar, Jai, Janse, Chris J, ...

Whole-genome comparisons are highly informative regarding genome evolution and can reveal the conservation of genome organization and gene content, gene regulatory elements, and presence of...

Gene Arrays at Pneumocystis carinii Telomeres

Keely, Scott P., Renauld, Hubert, Wakefield, Ann E., Cushion, Melanie T., Smulian, A. George, Fosker, Nigel, ...

In the fungus Pneumocystis carinii, at least three gene families (PRT1, MSR, and MSG) have the potential to generate high-frequency antigenic variation, which is likely to be a strategy by which this...

A New, Expressed Multigene Family Containing a Hot Spot for Insertion of Retroelements Is Associated with Polymorphic Subtelomeric Regions of Trypanosoma brucei

Bringaud, Frédéric, Biteau, Nicolas, Melville, Sara E., Hez, Stéphanie, El-Sayed, Najib M., Leech, Vanessa, ...

We describe a novel gene family that forms clusters in subtelomeric regions of Trypanosoma brucei chromosomes and partially accounts for the observed clustering of retrotransposons. The ingi and...

The Intestinal Protozoan Parasite Entamoeba histolytica Contains 20 Cysteine Protease Genes, of Which Only a Small Subset Is Expressed during In Vitro Cultivation

Bruchhaus, Iris, Loftus, Brendan J., Hall, Neil, Tannich, Egbert

Cysteine proteases are known to be important pathogenicity factors of the protozoan parasite Entamoeba histolytica. So far, a total of eight genes coding for cysteine proteases have been identified...

The DNA sequence of chromosome I of an African trypanosome: gene content, chromosome organisation, recombination and polymorphism

Hall, Neil, Berriman, Matthew, Lennard, Nicola J., Harris, Barbara R., Hertz-Fowler, Christiane, Bart-Delabesse, Emmanuelle N., ...

The African trypanosome, Trypanosoma brucei, causes sleeping sickness in humans in sub-Saharan Africa. Here we report the sequence and analysis of the 1.1 Mb chromosome I, which encodes approximately...

GeneDB: a resource for prokaryotic and eukaryotic organisms

Hertz-Fowler, Christiane, Peacock, Chris S., Wood, Valerie, Aslett, Martin, Kerhornou, Arnaud, Mooney, Paul, ...

GeneDB (http://www.genedb.org/) is a genome database for prokaryotic and eukaryotic organisms. The resource provides a portal through which data generated by the Pathogen Sequencing Unit at the...

Comparative Genomics of Transcriptional Control in the Human Malaria Parasite Plasmodium falciparum

Coulson, Richard M.R., Hall, Neil, Ouzounis, Christos A.

The life cycle of the parasite Plasmodium falciparum, responsible for the most deadly form of human malaria, requires specialized protein expression for survival in the mammalian host and insect...

An ancestral oomycete locus contains late blight avirulence gene Avr3a, encoding a protein that is recognized in the host cytoplasm

Armstrong, Miles R., Whisson, Stephen C., Pritchard, Leighton, Bos, Jorunn I. B., Venter, Eduard, Avrova, Anna O., ...

The oomycete Phytophthora infestans causes late blight, the potato disease that precipitated the Irish famines in 1846 and 1847. It represents a reemerging threat to potato production and is one of...

Plasmodium falciparum Variant Surface Antigen Expression Patterns during Malaria

Bull, Peter C, Berriman, Matthew, Kyes, Sue, Quail, Michael A, Hall, Neil, Kortok, Moses M, ...

The variant surface antigens expressed on Plasmodium falciparum–infected erythrocytes are potentially important targets of immunity to malaria and are encoded, at least in part, by a family of var...

The genetic map and comparative analysis with the physical map of Trypanosoma brucei

MacLeod, Annette, Tweedie, Alison, McLellan, Sarah, Taylor, Sonya, Hall, Neil, Berriman, Matthew, ...

Trypanosoma brucei is the causative agent of African sleeping sickness in humans and contributes to the debilitating disease ‘Nagana’ in cattle. To date we know little about the genes that...

A Plasmodium Whole-Genome Synteny Map: Indels and Synteny Breakpoints as Foci for Species-Specific Genes

Kooij, Taco W. A, Carlton, Jane M, Bidwell, Shelby L, Hall, Neil, Ramesar, Jai, Janse, Chris J, ...

Whole-genome comparisons are highly informative regarding genome evolution and can reveal the conservation of genome organization and gene content, gene regulatory elements, and presence of...

Gene Arrays at Pneumocystis carinii Telomeres

Keely, Scott P., Renauld, Hubert, Wakefield, Ann E., Cushion, Melanie T., Smulian, A. George, Fosker, Nigel, ...

In the fungus Pneumocystis carinii, at least three gene families (PRT1, MSR, and MSG) have the potential to generate high-frequency antigenic variation, which is likely to be a strategy by which this...

Common inheritance of chromosome Ia associated with clonal expansion of Toxoplasma gondii

Khan, Asis, Böhme, Ulrike, Kelly, Krystyna A., Adlem, Ellen, Brooks, Karen, Simmonds, Mark, ...

Toxoplasma gondii is a globally distributed protozoan parasite that can infect virtually all warm-blooded animals and humans. Despite the existence of a sexual phase in the life cycle, T. gondii has...

Royal Society Discussion Meeting: Utilising the Genome Sequence of Parasitic Protozoa

Hall, Neil

Protozoan parasites cause some of the world’s most important diseases. Genome sequencing information is rapidly being acquired and combined with new developments in functional genome analysis to...