Neil Hall

Whole genome sequencing of a natural recombinant Toxoplasma gondiistrain reveals chromosome sorting and local allelic variants (2009)

Bontell, Irene, Hall, Neil, Ashelford, Kevin E, Dubey, JP, Boyle, Jon P, Lindh, Johan, ...

Abstract Background Toxoplasma gondii is a zoonotic parasite of global importance. In common with many protozoan parasites it has the capacity for sexual recombination, but current evidence suggests...

doi:10.1016/j.pt.2005.01.002 (2009)

Serap Aksoy, Matt Berriman, Neil Hall, Masahira Hattori, Winston Hide, Michael J. Lehane

are abundant mitochondrion-related remnant organelles that lack a

Genome wide survey, discovery and evolution of repetitive elements in three Entamoeba species (2008)

Lorenzi, Hernan, Thiagarajan, Mathangi, Haas, Brian, Wortman, Jennifer, Hall, Neil, Caler, Elisabet

Abstract Background Identification and mapping of repetitive elements is a key step for accurate gene prediction and overall structural annotation of genomes. During the assembly and annotation of...

Letter Comparative Genomics of Transcriptional Control in the Human Malaria Parasite Plasmodium falciparum (2008)

Neil Hall, Christos A. Ouzounis

The life cycle of the parasite Plasmodium falciparum, responsible for the most deadly form of human malaria, requires specialized protein expression for survival in the mammalian host and insect...

Patterns of Evolution in the Unique tRNA Gene Arrays of the Genus Entamoeba (2008)

Tawari, Blessing, Ali, Ibne Karim M., Scott, Claire, Quail, Michael A., Berriman, Matthew, Hall, Neil, ...

Genome sequencing of the protistan parasite Entamoeba histolytica HM-1:IMSS revealed that almost all the tRNA genes are organized into tandem arrays that make up over 10% of the genome. The 25...

Royal Society Discussion Meeting: Utilising the Genome Sequence of Parasitic Protozoa (2006)

Neil Hall

Protozoan parasites cause some of the world’s most important diseases. Genome sequencing information is rapidly being acquired and combined with new developments in functional genome...

Common inheritance of chromosome Ia associated with clonal expansion of Toxoplasma gondii (2006)

Khan, Asis, Böhme, Ulrike, Kelly, Krystyna A., Adlem, Ellen, Brooks, Karen, Simmonds, Mark, ...

Toxoplasma gondii is a globally distributed protozoan parasite that can infect virtually all warm-blooded animals and humans. Despite the existence of a sexual phase in the life cycle, T. gondii has...

Common inheritance of chromosome Ia associated with clonal expansion of Toxoplasma gondii (2006)

Khan, Asis, Böhme, Ulrike, Kelly, Krystyna A., Adlem, Ellen, Brooks, Karen, Simmonds, Mark, ...

Toxoplasma gondii is a globally distributed protozoan parasite that can infect virtually all warm-blooded animals and humans. Despite the existence of a sexual phase in the life cycle, T. gondii has...

A Plasmodium Whole-Genome Synteny Map: Indels and Synteny Breakpoints as Foci for Species-Specific Genes (2005)

Jane M. Carlton, Shelby L. Bidwell, Neil Hall, Jai Ramesar, Chris J. Janse, ...

Whole-genome comparisons are highly informative regarding genome evolution and can reveal the conservation of genome organization and gene content, gene regulatory elements, and presence of...

Plasmodium falciparum Variant Surface Antigen Expression Patterns during Malaria (2005)

Peter C. Bull, Matthew Berriman, Sue Kyes, Michael A. Quail, Neil Hall, Moses M. Kortok, ...

The variant surface antigens expressed on Plasmodium falciparum–infected erythrocytes are potentially important targets of immunity to malaria and are encoded, at least in part, by a family of var...

The genetic map and comparative analysis with the physical map of Trypanosoma brucei (2005)

MacLeod, Annette, Tweedie, Alison, McLellan, Sarah, Taylor, Sonya, Hall, Neil, Berriman, Matthew, ...

Trypanosoma brucei is the causative agent of African sleeping sickness in humans and contributes to the debilitating disease ‘Nagana’ in cattle. To date we know little about the genes that...

The ingi and RIME non-LTR Retrotransposons Are Not Randomly Distributed in the Genome of Trypanosoma brucei (2004)

Bringaud, Frédéric, Biteau, Nicolas, Zuiderwijk, Eduard, Berriman, Matthew, El-Sayed, Najib M., Ghedin, Elodie, ...

The ingi (long and autonomous) and RIME (short and nonautonomous) non--long-terminal repeat retrotransposons are the most abundant mobile elements characterized to date in the genome of the African...

Evolutionary Pressures on Apicoplast Transit Peptides (2004)

Ralph, Stuart A., Foth, Bernardo J., Hall, Neil, McFadden, Geoffrey I.

Malaria parasites (species of the genus Plasmodium) harbour a relict chloroplast (the apicoplast) that is the target of novel anti-malarials. Numerous nuclear-encoded proteins are translocated into...

Comparative Genomics of Transcriptional Control in the Human Malaria Parasite Plasmodium falciparum (2004)

Coulson, Richard M.R., Hall, Neil, Ouzounis, Christos A.

The life cycle of the parasite Plasmodium falciparum, responsible for the most deadly form of human malaria, requires specialized protein expression for survival in the mammalian host and insect...

Evolutionary Pressures on Apicoplast Transit Peptides (2004)

Ralph, Stuart A., Foth, Bernardo J., Hall, Neil, McFadden, Geoffrey I.

Malaria parasites (species of the genus Plasmodium) harbor a relict chloroplast (the apicoplast) that is the target of novel antimalarials. Numerous nuclear-encoded proteins are translocated into the...

GeneDB: a resource for prokaryotic and eukaryotic organisms (2004)

Hertz-Fowler, Christiane, Peacock, Chris S., Wood, Valerie, Aslett, Martin, Kerhornou, Arnaud, Mooney, Paul, ...

GeneDB (http://www.genedb.org/) is a genome database for prokaryotic and eukaryotic organisms. The resource provides a portal through which data generated by the Pathogen Sequencing Unit at the...

Comparative Genomics of Transcriptional Control in the Human Malaria Parasite Plasmodium falciparum (2004)

Coulson, Richard M.R., Hall, Neil, Ouzounis, Christos A.

The life cycle of the parasite Plasmodium falciparum, responsible for the most deadly form of human malaria, requires specialized protein expression for survival in the mammalian host and insect...

Evolutionary Pressures on Apicoplast Transit Peptides (2004)

Ralph, Stuart A., Foth, Bernardo J., Hall, Neil, McFadden, Geoffrey I.

Malaria parasites (species of the genus Plasmodium) harbour a relict chloroplast (the apicoplast) that is the target of novel anti-malarials. Numerous nuclear-encoded proteins are translocated into...

Pilot survey of expressed sequence tags (ESTs) from the asexual blood stages of Plasmodium vivaxin human patients (2003)

Merino, Emilio F, Fernandez-Becerra, Carmen, Madeira, Alda MBN, Machado, Ariane L, Durham, Alan, Gruber, Arthur, ...

Abstract Background Plasmodium vivax is the most widely distributed human malaria, responsible for 70–80 million clinical cases each year and large socio-economical burdens for countries such as...

The DNA sequence of chromosome I of an African trypanosome: gene content, chromosome organisation, recombination and polymorphism (2003)

Hall, Neil, Berriman, Matthew, Lennard, Nicola J., Harris, Barbara R., Hertz-Fowler, Christiane, Bart-Delabesse, Emmanuelle N., ...

The African trypanosome, Trypanosoma brucei, causes sleeping sickness in humans in sub-Saharan Africa. Here we report the sequence and analysis of the 1.1 Mb chromosome I, which encodes approximately...

The ingi and RIME Non-LTR Retrotransposons Are Not Randomly Distributed in the Genome of Trypanosoma brucei (2003)

Bringaud, Frédéric, Biteau, Nicolas, Zuiderwijk, Eduard, Berriman, Matthew, El-Sayed, Najib M., Ghedin, Elodie, ...

The ingi (long and autonomous) and RIME (short and non-autonomous) non-long terminal repeat retrotransposons are the most abundant mobile elements characterized to date in the genome of the African...

The DNA sequence of chromosome I of an African trypanosome: gene content, chromosome organisation, recombination and polymorphism (2003)

Hall, Neil, Berriman, Matthew, Lennard, Nicola J., Harris, Barbara R., Hertz-Fowler, Christiane, Bart-Delabesse, Emmanuelle N., ...

The African trypanosome, Trypanosoma brucei, causes sleeping sickness in humans in sub‐Saharan Africa. Here we report the sequence and analysis of the 1.1 Mb chromosome I, which encodes...

The ingi and RIME Non-LTR Retrotransposons Are Not Randomly Distributed in the Genome of Trypanosoma brucei (2003)

Bringaud, Frédéric, Biteau, Nicolas, Zuiderwijk, Eduard, Berriman, Matthew, El-Sayed, Najib M., Ghedin, Elodie, ...

The ingi (long and autonomous) and RIME (short and non-autonomous) non-long terminal repeat retrotransposons are the most abundant mobile elements characterized to date in the genome of the African...

Abundant larval transcript-1 and -2 genes from Brugia malayi : diversity of genomic environments but conservation of 5ı promoter sequences functional in Caenorhabditis elegansı (2002)

Gomez-Escobar, Natalia, Gregory, William F, Britton, Collette, Murray, Linda, Corton, Craig, Hall, Neil, ...

The genomic organisation of two abundant larval transcript (alt) genes from the filarial nematode Brugia malayi has been defined. The products of these genes are 78% identical in amino acid sequence,...

Abundant larval transcript-1 and -2 genes from Brugia malayi : diversity of genomic environments but conservation of 5ı promoter sequences functional in Caenorhabditis elegansı (2002)

Gomez-Escobar, Natalia, Gregory, William F, Britton, Collette, Murray, Linda, Corton, Craig, Hall, Neil, ...

The genomic organisation of two abundant larval transcript (alt) genes from the filarial nematode Brugia malayi has been defined. The products of these genes are 78% identical in amino acid sequence,...

Royal Society Discussion Meeting: Utilising the Genome Sequence of Parasitic Protozoa (2001)

Neil Hall

Protozoan parasites cause some of the world’s most important diseases. Genome sequencing information is rapidly being acquired and combined with new developments in functional genome analysis to...

A New, Expressed Multigene Family Containing a Hot Spot for Insertion of Retroelements Is Associated with Polymorphic Subtelomeric Regions of Trypanosoma brucei

Bringaud, Frédéric, Biteau, Nicolas, Melville, Sara E., Hez, Stéphanie, El-Sayed, Najib M., Leech, Vanessa, ...

We describe a novel gene family that forms clusters in subtelomeric regions of Trypanosoma brucei chromosomes and partially accounts for the observed clustering of retrotransposons. The ingi and...

The Intestinal Protozoan Parasite Entamoeba histolytica Contains 20 Cysteine Protease Genes, of Which Only a Small Subset Is Expressed during In Vitro Cultivation

Bruchhaus, Iris, Loftus, Brendan J., Hall, Neil, Tannich, Egbert

Cysteine proteases are known to be important pathogenicity factors of the protozoan parasite Entamoeba histolytica. So far, a total of eight genes coding for cysteine proteases have been identified...

The DNA sequence of chromosome I of an African trypanosome: gene content, chromosome organisation, recombination and polymorphism

Hall, Neil, Berriman, Matthew, Lennard, Nicola J., Harris, Barbara R., Hertz-Fowler, Christiane, Bart-Delabesse, Emmanuelle N., ...

The African trypanosome, Trypanosoma brucei, causes sleeping sickness in humans in sub-Saharan Africa. Here we report the sequence and analysis of the 1.1 Mb chromosome I, which encodes approximately...

GeneDB: a resource for prokaryotic and eukaryotic organisms

Hertz-Fowler, Christiane, Peacock, Chris S., Wood, Valerie, Aslett, Martin, Kerhornou, Arnaud, Mooney, Paul, ...

GeneDB (http://www.genedb.org/) is a genome database for prokaryotic and eukaryotic organisms. The resource provides a portal through which data generated by the Pathogen Sequencing Unit at the...

Comparative Genomics of Transcriptional Control in the Human Malaria Parasite Plasmodium falciparum

Coulson, Richard M.R., Hall, Neil, Ouzounis, Christos A.

The life cycle of the parasite Plasmodium falciparum, responsible for the most deadly form of human malaria, requires specialized protein expression for survival in the mammalian host and insect...

An ancestral oomycete locus contains late blight avirulence gene Avr3a, encoding a protein that is recognized in the host cytoplasm

Armstrong, Miles R., Whisson, Stephen C., Pritchard, Leighton, Bos, Jorunn I. B., Venter, Eduard, Avrova, Anna O., ...

The oomycete Phytophthora infestans causes late blight, the potato disease that precipitated the Irish famines in 1846 and 1847. It represents a reemerging threat to potato production and is one of...

Plasmodium falciparum Variant Surface Antigen Expression Patterns during Malaria

Bull, Peter C, Berriman, Matthew, Kyes, Sue, Quail, Michael A, Hall, Neil, Kortok, Moses M, ...

The variant surface antigens expressed on Plasmodium falciparum–infected erythrocytes are potentially important targets of immunity to malaria and are encoded, at least in part, by a family of var...

The genetic map and comparative analysis with the physical map of Trypanosoma brucei

MacLeod, Annette, Tweedie, Alison, McLellan, Sarah, Taylor, Sonya, Hall, Neil, Berriman, Matthew, ...

Trypanosoma brucei is the causative agent of African sleeping sickness in humans and contributes to the debilitating disease ‘Nagana’ in cattle. To date we know little about the genes that...

A Plasmodium Whole-Genome Synteny Map: Indels and Synteny Breakpoints as Foci for Species-Specific Genes

Kooij, Taco W. A, Carlton, Jane M, Bidwell, Shelby L, Hall, Neil, Ramesar, Jai, Janse, Chris J, ...

Whole-genome comparisons are highly informative regarding genome evolution and can reveal the conservation of genome organization and gene content, gene regulatory elements, and presence of...

Gene Arrays at Pneumocystis carinii Telomeres

Keely, Scott P., Renauld, Hubert, Wakefield, Ann E., Cushion, Melanie T., Smulian, A. George, Fosker, Nigel, ...

In the fungus Pneumocystis carinii, at least three gene families (PRT1, MSR, and MSG) have the potential to generate high-frequency antigenic variation, which is likely to be a strategy by which this...

A New, Expressed Multigene Family Containing a Hot Spot for Insertion of Retroelements Is Associated with Polymorphic Subtelomeric Regions of Trypanosoma brucei

Bringaud, Frédéric, Biteau, Nicolas, Melville, Sara E., Hez, Stéphanie, El-Sayed, Najib M., Leech, Vanessa, ...

We describe a novel gene family that forms clusters in subtelomeric regions of Trypanosoma brucei chromosomes and partially accounts for the observed clustering of retrotransposons. The ingi and...

The Intestinal Protozoan Parasite Entamoeba histolytica Contains 20 Cysteine Protease Genes, of Which Only a Small Subset Is Expressed during In Vitro Cultivation

Bruchhaus, Iris, Loftus, Brendan J., Hall, Neil, Tannich, Egbert

Cysteine proteases are known to be important pathogenicity factors of the protozoan parasite Entamoeba histolytica. So far, a total of eight genes coding for cysteine proteases have been identified...

The DNA sequence of chromosome I of an African trypanosome: gene content, chromosome organisation, recombination and polymorphism

Hall, Neil, Berriman, Matthew, Lennard, Nicola J., Harris, Barbara R., Hertz-Fowler, Christiane, Bart-Delabesse, Emmanuelle N., ...

The African trypanosome, Trypanosoma brucei, causes sleeping sickness in humans in sub-Saharan Africa. Here we report the sequence and analysis of the 1.1 Mb chromosome I, which encodes approximately...

GeneDB: a resource for prokaryotic and eukaryotic organisms

Hertz-Fowler, Christiane, Peacock, Chris S., Wood, Valerie, Aslett, Martin, Kerhornou, Arnaud, Mooney, Paul, ...

GeneDB (http://www.genedb.org/) is a genome database for prokaryotic and eukaryotic organisms. The resource provides a portal through which data generated by the Pathogen Sequencing Unit at the...

Comparative Genomics of Transcriptional Control in the Human Malaria Parasite Plasmodium falciparum

Coulson, Richard M.R., Hall, Neil, Ouzounis, Christos A.

The life cycle of the parasite Plasmodium falciparum, responsible for the most deadly form of human malaria, requires specialized protein expression for survival in the mammalian host and insect...

An ancestral oomycete locus contains late blight avirulence gene Avr3a, encoding a protein that is recognized in the host cytoplasm

Armstrong, Miles R., Whisson, Stephen C., Pritchard, Leighton, Bos, Jorunn I. B., Venter, Eduard, Avrova, Anna O., ...

The oomycete Phytophthora infestans causes late blight, the potato disease that precipitated the Irish famines in 1846 and 1847. It represents a reemerging threat to potato production and is one of...

Plasmodium falciparum Variant Surface Antigen Expression Patterns during Malaria

Bull, Peter C, Berriman, Matthew, Kyes, Sue, Quail, Michael A, Hall, Neil, Kortok, Moses M, ...

The variant surface antigens expressed on Plasmodium falciparum–infected erythrocytes are potentially important targets of immunity to malaria and are encoded, at least in part, by a family of var...

The genetic map and comparative analysis with the physical map of Trypanosoma brucei

MacLeod, Annette, Tweedie, Alison, McLellan, Sarah, Taylor, Sonya, Hall, Neil, Berriman, Matthew, ...

Trypanosoma brucei is the causative agent of African sleeping sickness in humans and contributes to the debilitating disease ‘Nagana’ in cattle. To date we know little about the genes that...

A Plasmodium Whole-Genome Synteny Map: Indels and Synteny Breakpoints as Foci for Species-Specific Genes

Kooij, Taco W. A, Carlton, Jane M, Bidwell, Shelby L, Hall, Neil, Ramesar, Jai, Janse, Chris J, ...

Whole-genome comparisons are highly informative regarding genome evolution and can reveal the conservation of genome organization and gene content, gene regulatory elements, and presence of...

Gene Arrays at Pneumocystis carinii Telomeres

Keely, Scott P., Renauld, Hubert, Wakefield, Ann E., Cushion, Melanie T., Smulian, A. George, Fosker, Nigel, ...

In the fungus Pneumocystis carinii, at least three gene families (PRT1, MSR, and MSG) have the potential to generate high-frequency antigenic variation, which is likely to be a strategy by which this...

Common inheritance of chromosome Ia associated with clonal expansion of Toxoplasma gondii

Khan, Asis, Böhme, Ulrike, Kelly, Krystyna A., Adlem, Ellen, Brooks, Karen, Simmonds, Mark, ...

Toxoplasma gondii is a globally distributed protozoan parasite that can infect virtually all warm-blooded animals and humans. Despite the existence of a sexual phase in the life cycle, T. gondii has...

Royal Society Discussion Meeting: Utilising the Genome Sequence of Parasitic Protozoa

Hall, Neil

Protozoan parasites cause some of the world’s most important diseases. Genome sequencing information is rapidly being acquired and combined with new developments in functional genome analysis to...

Whole genome sequencing of a natural recombinant Toxoplasma gondii strain reveals chromosome sorting and local allelic variants

Bontell, Irene Lindström, Hall, Neil, Ashelford, Kevin E, Dubey, JP, Boyle, Jon P, Lindh, Johan, ...

Extensive sequence analysis of eight Toxoplasma gondii isolates from Uganda has revealed chromosome sorting and local allelic variants.