Niamh Roche

Functional Adaptation of BabA, the H. pylori ABO Blood Group Antigen Binding Adhesin (2004)

Aspholm-Hurtig, Marina, Dailide, Giedrius, Lahmann, Martina, Kalia, Awdhesh, Ilver, Dag, Roche, Niamh, ...

Adherence by Helicobacter pylori increases the risk of gastric disease. Here, we report that more than 95% of strains that bind fucosylated blood group antigen bind A, B, and O antigens...

Glycoconjugate Binding of Gastric and Enterohepatic Helicobacter spp. (2003)

Hynes, Sean O, Teneberg, Susann, Roche, Niamh, Wadström, Torkel

Helicobacter pylori is able to utilize several lectin-like, protein-carbohydrate interactions for binding to mucins, cell surfaces, and extracellular matrix proteins. As determined by...

Helicobacter pylori SabA adhesin in persistent infection and chronic inflammation (2002)

Mahdavi, Jafar, Sondén, Berit, Hurtig, Marina, Olfat, Farzad O., Forsberg, Lina, Roche, Niamh, ...

Helicobacter pylori adherence in the human gastric mucosa involves specific bacterial adhesins and cognate host receptors. Here, we identify sialyl-dimeric-Lewis x glycosphingolipid as a receptor for...

Helicobacter pylori-binding gangliosides of human gastric adenocarcinoma (2001)

Roche, Niamh, Larsson, Thomas, Ångström, Jonas, Teneberg, Susann

Acidic and neutral glycosphingolipids were isolated from a human gastric adenocarcinoma, and binding of Helicobacter pylori to the isolated glycosphingolipids was assessed using the chromatogram...

Glycosphingolipid Binding Specificities of Rotavirus: Identification of a Sialic Acid-Binding Epitope

Delorme, Cécile, Brüssow, Harald, Sidoti, Josette, Roche, Niamh, Karlsson, Karl-Anders, Neeser, Jean-Richard, ...

The glycosphingolipid binding specificities of neuraminidase-sensitive (simian SA11 and bovine NCDV) and neuraminidase-insensitive (bovine UK) rotavirus strains were investigated using the thin-layer...

Glycoconjugate Binding of Gastric and Enterohepatic Helicobacter spp.

Hynes, Sean O., Teneberg, Susann, Roche, Niamh, Wadström, Torkel

Helicobacter pylori is able to utilize several lectin-like, protein-carbohydrate interactions for binding to mucins, cell surfaces, and extracellular matrix proteins. As determined by...

Helicobacter pylori and Complex Gangliosides

Roche, Niamh, Ångström, Jonas, Hurtig, Marina, Larsson, Thomas, Borén, Thomas, Teneberg, Susann

Recognition of sialic acid-containing glycoconjugates by the human gastric pathogen Helicobacter pylori has been repeatedly demonstrated. To investigate the structural requirements for H. pylori...

Glycosphingolipid Binding Specificities of Rotavirus: Identification of a Sialic Acid-Binding Epitope

Delorme, Cécile, Brüssow, Harald, Sidoti, Josette, Roche, Niamh, Karlsson, Karl-Anders, Neeser, Jean-Richard, ...

The glycosphingolipid binding specificities of neuraminidase-sensitive (simian SA11 and bovine NCDV) and neuraminidase-insensitive (bovine UK) rotavirus strains were investigated using the thin-layer...

Glycoconjugate Binding of Gastric and Enterohepatic Helicobacter spp.

Hynes, Sean O., Teneberg, Susann, Roche, Niamh, Wadström, Torkel

Helicobacter pylori is able to utilize several lectin-like, protein-carbohydrate interactions for binding to mucins, cell surfaces, and extracellular matrix proteins. As determined by...

Helicobacter pylori and Complex Gangliosides

Roche, Niamh, Ångström, Jonas, Hurtig, Marina, Larsson, Thomas, Borén, Thomas, Teneberg, Susann

Recognition of sialic acid-containing glycoconjugates by the human gastric pathogen Helicobacter pylori has been repeatedly demonstrated. To investigate the structural requirements for H. pylori...