Wilson, Nicholas S., Behrens, Georg M. N., Lundie, Rachel J., Smith, Christopher M., Waithman, Jason, Young, Louise, ...
The mechanisms responsible for the immunosuppression associated with sepsis or some chronic blood infections remain poorly understood. Here we show that infection with a malaria parasite (Plasmodium...
The dominant role of CD8+ dendritic cells in cross-presentation is not dictated by antigen capture
Schnorrer, Petra, Behrens, Georg M. N., Wilson, Nicholas S., Pooley, Joanne L., Smith, Christopher M., El-Sukkari, Dima, ...
Mouse spleens contain three populations of conventional (CD11chigh) dendritic cells (DCs) that play distinct functions. The CD8+ DC are unique in that they can present exogenous antigens on their MHC...
Young, Louise J., Wilson, Nicholas S., Schnorrer, Petra, Mount, Adele, Lundie, Rachel J., La Gruta, Nicole L., ...
When dendritic cells (DCs) encounter signals associated with infection or inflammation, they become activated and undergo maturation. Mature DCs are very efficient at presenting antigens captured in...